Kristen is board-certified in both Internal Medicine and Infectious Diseases and a lead clinical investigator and site Principal Investigator at the Vaccine Testing Center (VTC) at UVM. Kristen's clinical practice consists of inpatient consultative ID and outpatient HIV, STI, travel and general infectious disease. Kristen is currently engaged in a variety of service activities for the College of Medicine, the Department of Medicine, our ID Division and UVMMC at large. In addition, Kristen provides mentorship to a variety of individuals including medical students, residents, fellows and physician colleagues. Kristen has lectured regionally on a variety of topics and internationally regarding Flavivirus vaccine development.
Nationally, Kristen is actively engaged in society memberships (IDSA and ASTMH) and have served as a reviewer for Critical Care Medicine as well as The American Society of Tropical Medicine and Hygiene. Kristen has served on the American Council of Immunization Practices, Flavivirus Working Group and on an international level she has served on the Candidate Vaccine Advisory Committee (CVAC) Steering Group on preparedness for Flavivirus Vaccines, Indian/US working group (Indo-VAP).
Kristen's research work focuses mainly on vaccine research. Kristen's focus is primarily on flavivirus vaccine research. In conjunction with her collaborators the National Institutes of Health (NIH) and Johns Hopkins Bloomberg School of Public Health, Kristen has been examining the safety, efficacy and immunogenicity of a Live-attenuated Dengue Vaccine, a West Nile Virus Vaccine and a Zika vaccine. Kristen works closely with collaborators at JHU and the NIH to determine what next steps/studies will need to be developed based on the results of each individual trial.
In addition, the work UVM has expanded to encompass Controlled Human Infection Models (CHIM) for many of these same pathogens. This a unique area of vaccine research requiring a thorough understanding of the characteristics of the pathogen, the disease state and the complex interplay between human host and pathogen. Kristen's role as the site principal investigator at the Vaccine Testing Center at UVM has been integral in developing our CHIM at UVM.