The University of Vermont Cancer Center's Protocol Review and Monitoring System (PRMS) provides a centralized system for review and monitoring of cancer clinical trials.
Within PRMS, the Protocol Review and Monitoring Committee (PRMC) is a multidisciplinary committee charged with evaluating the scientific merit of cancer-related clinical research at the University of Vermont Cancer Center. The PRMC has the authority to approve and authorize activation of cancer research studies which should align with the scientific priorities of the University of Vermont Cancer Center (UVMCC). The PRMC does not duplicate or have overlapping responsibilities with IRB(s) or the UVMCC Data Safety Monitoring Committee (DSMC).