College of Arts and Sciences

Yangguang Ou

Assistant Professor - Analytical Chemistry, Bioanalytical Chemistry, Neurochemistry

Yangguang Ou
Alma mater(s)
  • B.S. Biochemistry — Florida State University, 2011
  • B.S. Chemistry — Florida State University, 2011
  • Ph.D. Analytical Chemistry — University of Pittsburgh, 2017
  • Postdoctoral Researcher — University of South Carolina, 2018-2020

Areas of expertise

Bioanalytical Chemistry, Neurochemistry, Biochemistry, Depression, PTSD, Autism Spectrum Disorder, Electrochemical Sensing, Separations, Neuropeptides, Neurotransmitters, Voltammetry, Carbon Fiber Microelectrodes

BIO

The Ou lab is a bio analytical group that primarily works with fast scan cyclic voltammetry at carbon fiber microelectrodes. Their interests include : 1) enhancing the selectivity of carbon fiber microelectrodes, including using different waveforms, molecular imprinting approaches, and ethynyl linkers, 2) elucidating the electroactivity of short chain fatty acids on carbon fiber, including understanding the mechanism of redox activity, and 3) understanding the role of short chain fatty acids in neurotransmission. The Ou lab also collaborates with the Punihaole lab in quantifying the oxidative stress associated with fibril polymorphic cytotoxicity as related to Alzheimer’s and Cerebral Amyloid Angiopathy.

Publications

Yangguang Ou Publications (docx)

Awards and Achievements

2019 – The Midwest Universities Analytical Chemistry Conference Travel Award
2015 – 2016 – Andrew Mellon Fellowship
2011 – 2013 – Arts & Sciences Fellowship

Bio

The Ou lab is a bio analytical group that primarily works with fast scan cyclic voltammetry at carbon fiber microelectrodes. Their interests include : 1) enhancing the selectivity of carbon fiber microelectrodes, including using different waveforms, molecular imprinting approaches, and ethynyl linkers, 2) elucidating the electroactivity of short chain fatty acids on carbon fiber, including understanding the mechanism of redox activity, and 3) understanding the role of short chain fatty acids in neurotransmission. The Ou lab also collaborates with the Punihaole lab in quantifying the oxidative stress associated with fibril polymorphic cytotoxicity as related to Alzheimer’s and Cerebral Amyloid Angiopathy.

Awards and Achievements

2019 – The Midwest Universities Analytical Chemistry Conference Travel Award
2015 – 2016 – Andrew Mellon Fellowship
2011 – 2013 – Arts & Sciences Fellowship

Research and/or Creative Works

Our lab develops and optimizes analytical methods (including sampling, microfluidics, and electrochemical sensing technology) to make quantitative measurements of a range of analytes. These analytes include molecules produced by the gut microbiome (such as short chain fatty acids), contaminants in water ecosystems (i.e. heavy metals), and those responsible for signaling in the central nervous system (i.e. neurotransmitters and neuropeptides).

We utilize a variety of surface chemistry to make our sensing devices, including but not limited to ionophores and molecular imprinting technology.

Check out our lab website for more information!