Assistant Professor, Graduate Program Director

Amber Doiron is Assistant Professor in the Department of Electrical and Biomedical Engineering at the University of Vermont. Her research focuses on the development of materials for use in drug delivery, wound dressings, and as contrast agents in magnetic resonance imaging. Applications of her work focus on the prevention and treatment of bacterial biofilm infections, detection of inflammation and reactive oxygen species, as well as studying cell-nanoparticle interactions. Doiron earned a M.S. and Ph.D. in biomedical engineering from the University of Texas at Austin and was the T. Chen Fong Postdoctoral Fellow in radiology and chemical engineering at the University of Calgary in Alberta, Canada. She was also the chief scientific officer at NanoPulse Biosciences, a startup company focused on biomedical applications of gold nanoparticles, for four years.

Publications

  • Nwasike, C., Purr, E., Nagi, J.S., Mahler, G.J., Doiron, A.L. (2023). Incorporation of Targeting Biomolecule Improves Interpolymer Complex-Superparamagnetic Iron Oxide Nanoparticles Attachment to and Activation of T2 MR Signals in M2 Macrophages. International Journal of Nanomedicine 18: 473-487. doi: 10.2147/IJN.S392567
  • Nwasike, C., Purr, E., Yoo, E., Nagi, J.S., Doiron, A.L. (2021). Activatable Nanoparticles: Recent Advances in Redox-Sensitive Magnetic Resonance Contrast Agent Candidates Capable of Detecting Inflammation. Invited paper, Pharmaceutics 14(1):69. doi: 10.3390/ph14010069
  • Nagi, J.S., Skorenko, K., Bernier, W.E., Jones, W.E., Doiron, A.L. (2020). Near Infrared-Activated Dye-Linked ZnO Nanoparticles Release Reactive Oxygen Species for Potential Use in Photodynamic Therapy. Materials 13(1). doi: 10.3390/ma13010017
  • Han, C., Goodwine, J., Romero, N., Sauer, K., Doiron, A.L. (2019). Enzyme-encapsulating polymeric nanoparticles: a potential adjunctive therapy in Pseudomonas aeruginosa biofilm-associated infection treatments. Colloids and Surfaces B 184:110512. doi:10.1016/j.colsurfb.2019.110512. *Cover Image
  • Goodwine, J., Gil, J., Doiron, A., Valdes, J., Solis, M., Higa, A., Davis, S., Sauer, K. (2019). Pyruvate-depleting conditions induce biofilm dispersion and enhance the efficacy of antibiotics in killing biofilms in vitro and in vivo. Scientific Reports, 9(1):3763. doi: 10.1038/s41598-019-40378-z
  • Gomez-Garcia, J., Doiron, A.L., Steele R., Labouta, H.I., Vafadar, B., Shepherd R.D., Gates, I.D., Cramb, D.T., Childs S., Rinker K.D. (2018). Nanoparticle Localization in Blood vessels: Dependence on fluid shear stress, flow disturbances, and flow-induced changes in endothelial physiology. Nanoscale, 10, 15249-15261. doi: 10.1039/C8NR03440K
  • Yoo, E., Liu, Y., Nwasike, C., Weith, A., Cordovez, B., Earhart, C., Doiron, A.L. (2018). Surface characterization of nanoparticles using near field light scattering. Beilstein Journal of Nanotechnology, 9, 1228–1238. doi: 10.3762/bjnano.9.114
  • Liu, Y., Yoo, E., Han, C., Mahler, G., Doiron, A.L. (2018). Endothelial Barrier Dysfunction Induced by Nanoparticle Exposure Through Actin Remodeling via Caveolae/Raft-Regulated Calcium Signaling. NanoImpact 11:82-91. doi: 10.1016/j.impact.2018.02.007
  • Liu, Y., Rogel, N., Harada, K., Jarret, L., Maiorana, C.H., German, G.K., Mahler, G., Doiron, A.L. (2017). Nanoparticle Size-Specific Actin Rearrangement and Barrier Dysfunction of Endothelial Cells. Nanotoxicology, 11(7):846-856. doi: 10.1080/17435390.2017.1371349; PMID: 28885066.
  • Yoo, E., Cheng, H.A., Nardacci, L.E., Beaman, D., Lee, C., Fishbein, K.W., Spencer, R.G.S., Fisher, O.Z., Doiron, A.L. (2017). Activatable Interpolymer Complex-Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Contrast Agents Sensitive to Oxidative Stress. Colloids and Surfaces B: Biointerfaces, 158: 578-588. doi: 10.1016/j.colsurfb.2017.07.025; PMID: 28750340.
  • Bromberg, L.A., Sanchez, S., Doiron, A., Lyles, M., German, G. (2017). Non-ionising UV light increases the optical density of hygroscopic self assembled DNA crystal films. Scientific Reports 7, Article number 6631. doi: 10.1038/s41598-017-06884-8; PMID: 28747733.
Associate Professor & Graduate Program Director Amber Doiron

Areas of Expertise and/or Research

Biomaterials, Nanotechnology, Drug Delivery, Molecular Imaging, Magnetic Resonance Imaging

Education

  • M.S. and Ph.D. in Biomedical Engineering, University of Texas at Austin

Contact

Email:

amber.doiron@uvm.edu

Phone:
  • 802-656-3382
Office Location:

Votey 309C

Website(s):
  1. Lab Website

Courses Taught

  • BME 5150 Nanobiomaterials
  • BME 2050 Materials and Transport