Microscopy Imaging and Cytometry

We respectfully request that users acknowledge University of Vermont (UVM) Microscopy Imaging and Cytometry in any publications resulting from use of the facility or its services. Anyone who uses the MIC should include a General Acknowledgement in their publication. 

CBSR Acknowledgement Guidelines (PDF)Imaging work was performed at the Microscopy Imaging and Cytometry Center at Larner College of Medicine (RRID# SCR_018821). 

If you used specific equipment that was purchased with grant funding (AFM, confocal, VERSA whole slide imager) the corresponding grant information should be added.  For grant language for those instruments, visit Instruments - UVM's Microscopy Imaging and Cytometry, go to the instrument, and expand. Language will be listed just under the equipment description.

VBRN Proteomics Facility

The National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), which funds the Vermont Biomedical Research Network (VBRN), requires that we acknowledge them as the source of funding that supports your work whenever you publish papers, chapters, abstracts or otherwise present your work if you have accessed services in a VBRN Core Facility. Please acknowledge the VBRN grant by number and cite the specific VBRN Core(s) (RRID# SCR_018667) at the University of Vermont in all publications and grant applications if you are using data or tools generated in a VBRN Core.

Visit How to Cite VBRN for more detail information on the citing the VBRN Proteomics Facility 

Citing the Bioinformatics Shared Resource

The Bioinformatics Shared Resource core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493)

Citing the Genome Technologies Core 

Please remember to cite the University of Vermont Integrative Genomics Resource Core Facility (VIGR) and/or Microarray (if used after July 1, 2017) and/or Massively Parallel Sequencing Facilities in your abstracts and publications.

This core provides services for Experimental Design, Metagenomics, Comparative Expression Analyses, Variant Analyses, and Systems Biology. Overarching umbrella encompassing three distinct shared resource facility arms: DNA Analysis, Microarray, and Massively Parallel Sequencing Facilities.

University of Vermont Integrative Genomics Resource Core Facility (RRID:SCR_021775)

Language for Automated DNA sequencing for other automated DNA Sequencing (or other molecular analyses, i.e. rtQPCR, Molecular Imaging, etc):

"The automated DNA sequencing (or other molecular analyses, i.e. rtQPCR, Molecular Imaging, etc.) was performed in Vermont Integrative Genomics Resource DNA Facility and was supported by University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, and the UVM Larner College of Medicine."

Language for Target Preparation and Array Hybridization:

"The target preparation and array hybridization was performed in the Vermont Integrative Genomics Resource Microarray Facility and was supported by the University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, UVM College of Agriculture and Life Sciences, and the UVM Larner College of Medicine."

Language for Use of Next-Generation Sequencing:

"The next-generation sequencing was performed in the Vermont Integrative Genomics Resource Massively Parallel Sequencing Facility and was supported by the University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, UVM College of Agriculture and Life Sciences, and the UVM Larner College of Medicine."

For all other services:

Research reported in this (publication, release) was supported by Advanced Genome Technologies Core of the University of Vermont and the Larner College of Medicine. Vermont Integrative Genomics Resource Facility (RRID# SCR_021775).

Process to propose purchase or acquisition of any lab equipment for or to the cores located within CBSR core spaces:

1. Review and complete the Policy on Accepting Donated Instruments (PDF)
2. Email along with a business plan (ODF format) to CBSR at: CBSR@med.uvm.edu 

(v.1 Jun 2024)

Process and Policy for Retiring Laboratory Equipment Center for Biomedical Shared Resources (CBSR)

Laboratory equipment may be retired for many reasons. It may be due to the equipment not performing to the degree it once did, no longer supported by the manufacturer, service contracts discontinued, or the technology becomes obsolete and there are newer more efficient options, or other extenuatuating circumstances. Below we outline the steps to be taken prior to any piece of shared resource equipment retiring out of a core. 

1. The applicable core director will submit a notice of plan to sunset the instrument to the CBSR Director and Internal Advisory Committee for their review and comments.
2. The core responsible for the piece of equipment will inform clients and users via email that the instrument will be sunsetted and no longer available in the core. The reason for this decision will be provided with an ample timeline for researchers to respond.
3. The core responsible for the instrument will provide clients and users with information regarding potential replacement options (if applicable).
4. If the core responsible for the instrument will not be replacing with it with a similar substitute technology, then that core, to the best of their ability, will provide the clients and users with potential alternative options for having their work requests processed.
5. The core will be open to feedback and questions from their clients and users and do their best to satisfy their continued research requests.

 (v.1 Jun 2024) 

Process and Policy for Retiring Laboratory Equipment Center for Biomedical Shared Resources (PDF)

Center for Biomedical Shared Resources (CBSR) Rigor and Reproducibility Policy

The core facilities comprising the CBSR at the University of Vermont are dedicated to providing clients with data that are both scientifically rigorous and reproducible. To accomplish these goals, we offer the following Rigor and Reproducibility guidelines for our clients: 

• Consult with the core staff in the planning stage. Consult with a statistician if you need help developing a Power Analysis to assure that your results will be adequately powered.
• Design your experiment with sufficient controls (rigor) and appropriate replicates (reproducibility).
• Assure that ALL of your reagents (antibodies, cell lines, mice) are fully validated.
• Have a clear and detailed protocol (SOP) and data analysis plan. Assure that the protocol is strictly followed or that any deviation is well documented.
• Assure that the staff or students performing the experiment are well trained and understand each step and the importance of performing them precisely.
• Consult with core staff for best practices regarding image processing and analysis.
• Consult with core staff regarding ethical standards for image manipulation.
• Use only well-maintained instrumentation, preferably maintained and operated in a core facility with expert staff (see #1 above).
• Document all steps, reagents, equipment and data analysis methods used in the experiment. Assure that the both the documentation and the data itself are properly stored in a safe data management repository.
• You are encouraged to share experimental protocols, results, and data acquired in a core prior to submission of a manuscript for publication.
• Acknowledge all grants that support the core (NIH S10, etc.), the core (by name, including its specific RRID#), and core staff in publications.

Center for Biomedical Shared Resources (CBSR) Rigor and Reproducibility Policy (PDF)

*See the following manuscript for more details: 

Ott AW, Sol-Church K, Deshpande GM, Knudston KL, Meyn SM, Mische SM, Taatjes DJ, Sturges MR, Gregory CW (2022) Rigor, reproducibility, and transparency in shared research resources: Follow-up survey and recommendations for improvements. J Biomolec Tech 33(3).   Doi: 10.7171/3fc1f5fe.fa789303.