Services of the Genome Technologies core include the following: (more needed here)

• Proper prep and design for your experiments
• Support of genomic sequencing of all -omics 

We do this by using primarily two process types, Massively Parallel Sequencing (MPS) and General Genomic Services (GGS). For more detail look under the Instrumentation section.

How to get your data?  The VACC provides access to two HPCs: 

• “Bluemoon,” a multi-thousand-core, high-performance computing cluster, supporting largescale computation, low-latency networking for MPI workloads, large memory systems, and high-performance parallel file systems.
• "Big Green,” a massively parallel cluster composed of over 80 GPUs capable of over 8 petaflops of mixed precision calculations based on the NVIDIA Tesla V100 architecture. Its hybrid design and parallelism can expedite and support high-throughput artificial intelligence and machine learning workflows

Massively Parallel Sequencing (MPS): MPS services include: single-cell genomic analysis, chromosome conformation capture techniques, RNA-Seq, Exome-Seq, ChIP-Seq, Methyl-Seq, whole genome sequencing, metagenomics and microbiome, and small RNA sequencing to name a few. Major equipment includes:

• Singular G4 sequencer plus the Illumina MiSeq sequencer for short reads
• Oxford Nanopore GridION X5 MK2 and P2 Solo, and 3 Oxford Nanopore MinION MK1B for long read sequencing
• 10x Single Cell Genomics System

General Genomic Services (GGS): GGS provides a vast array of analysis services including DNA/RNA extraction, PCR and PCR troubleshooting, primer design, Sanger sequencing, (SNP/MSI/AFLP), human cell line authentication, quantitative PCR, nucleic acid and protein quantification.  Major equipment includes:

• ABI SeqStudio Genetic Analyzer (4 capillary)
• ABI Quant Studio 6 RTqPCR system and Prism 7500 Fast RTqPCR
• BioRad QX200 Digital Droplet qPCR
• BioRad QRS+ ChemiDoc imagers
• Agilent 2100 Bioanalyzer
• NanoDrop (ND-1000) Spectrophotometer
• Quantas Spectrofluorometers, and 3 Qubit spectrofluorometer
• Logo Quantum Microbial imager
• Zeiss digital AxioScope with DIC and full spectrum fluorescence
• Benchmark Beadbug6 Homogenizer
• 4 PCR free Clean Air HEPA cabinets; 1 Biosafety II hood
• Savant SpeedVac
• Thermo Omni Bead Ruptor 24 Elite
• 4 Biometra TAdvanced 60 Thermal Cyclers with Exchangeable Blocks

Information here about how to get your data?  The VACC provides access to two HPCs 

• “Bluemoon,” a multi-thousand-core, high-performance computing cluster, supporting largescale computation, low-latency networking for MPI workloads, large memory systems, and high-performance parallel file systems.
• "Big Green,” a massively parallel cluster composed of over 80 GPUs capable of over 8 petaflops of mixed precision calculations based on the NVIDIA Tesla V100 architecture. Its hybrid design and parallelism can expedite and support high-throughput artificial intelligence and machine learning workflows

Please remember to cite the University of Vermont Integrative Genomics Resource Core Facility (VIGR) and/or Microarray (if used after July 1, 2017) and/or Massively Parallel Sequencing Facilities in your abstracts and publications.

This core provides services for Experimental Design, Metagenomics, Comparative Expression Analyses, Variant Analyses, and Systems Biology. Overarching umbrella encompassing three distinct shared resource facility arms: DNA Analysis, Microarray, and Massively Parallel Sequencing Facilities.

University of Vermont Integrative Genomics Resource Core Facility (RRID:SCR_021775)

"The automated DNA sequencing (or other molecular analyses, i.e. rtQPCR, Molecular Imaging, etc.) was performed in Vermont Integrative Genomics Resource DNA Facility and was supported by University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, and the UVM Larner College of Medicine."

The target preparation and array hybridization was performed in the Vermont Integrative Genomics Resource Microarray Facility and was supported by the University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, UVM College of Agriculture and Life Sciences, and the UVM Larner College of Medicine."

"The next-generation sequencing was performed in the Vermont Integrative Genomics Resource Massively Parallel Sequencing Facility and was supported by the University of Vermont Cancer Center, Lake Champlain Cancer Research Organization, UVM College of Agriculture and Life Sciences, and the UVM Larner College of Medicine."