Larner College of Medicine

Adam Sprouse-Blum

Associate Professor, Neurological Sciences

Researcher smiling posed against a grey background
Alma mater(s)
  • M.D., University of Hawaii
  • Ph.D., Clinical & Translational Science, University of Vermont
  • Residency, Family Medicine, Bronx-Lebanon Hospital
  • Fellowship, Research, University of Vermont
  • Fellowship, Headache Medicine, University of Vermont
Affiliated Department(s)

Department of Neurological Sciences

Areas of expertise

migraine, neuroimaging, basic science, brain cooling

BIO

Adam Sprouse-Blum, MD, PhD, is an Associate Professor of Neurological Sciences at the University of Vermont Larner College of Medicine. His research focuses on two main areas: (1) migraine epidemiology and pathophysiology, using approaches including longitudinal databases, neuroimaging, and animal models; and (2) non-invasive brain cooling as a therapeutic intervention for neurologic disease, including applications in cardiac arrest and heat-related illness.

Publications

PubMed Publications

Awards and Achievements

  • 2016: Frontiers in Headache Research Scholarship
  • 2016: International Headache Academy Travel Grant

Bio

Adam Sprouse-Blum, MD, PhD, is an Associate Professor of Neurological Sciences at the University of Vermont Larner College of Medicine. His research focuses on two main areas: (1) migraine epidemiology and pathophysiology, using approaches including longitudinal databases, neuroimaging, and animal models; and (2) non-invasive brain cooling as a therapeutic intervention for neurologic disease, including applications in cardiac arrest and heat-related illness.

Awards and Achievements

  • 2016: Frontiers in Headache Research Scholarship
  • 2016: International Headache Academy Travel Grant

Select Publications

  1. Sprouse Blum, A. S., Wilkinson, K. S., Sparks, A. D., Littenberg, B., Zakai, N. A., Judd, S. E., ... & Cushman, M. (2026). Migraine and Ischemic Stroke Risk in Middle and Older Age: The REGARDS Cohort. Neurology Open Access, 2(2), e000107. 
  2. Sprouse Blum, A. S., Watts, R., Hipko, S. G., Gonyea, J. V., Senft-Miller, A. E., Nop, O. K., ... & Zhang, J. (2026). Cerebrovascular reactivity in migraine: a breath-hold BOLD fMRI study. The Journal of Headache and Pain, 27(1), 168. 
  3. Sprouse Blum, A. S., Zenger, S. K., Nguyen, A. H., Parra, J. R., Stahl, E. D., Littenberg, B., ... & Mirbagheri, S. (2025). Association between headache laterality in migraine and hemispheric distribution of white matter hyperintensities on MRI. Journal of Neurology, 272(1), 18. 
  4. Sprouse Blum, A. S., DaSilva, L. A., Greenberg, M. D., Nissenbaum, A. J., Shapiro, R. E., & Littenberg, B. (2024). Comparison of migraine with left‐versus right‐sided headache: A cross‐sectional study. Headache: The Journal of Head and Face Pain, 64(3), 259-265. 
  5. Blum, A. S. S., Riggins, N. Y., Hersey, D. P., Atwood, G. S., & Littenberg, B. (2023). Left-vs right-sided migraine: a scoping review. Journal of Neurology, 270(6), 2938-2949.

Google Scholar Publications