Larner College of Medicine

About the LCBR

The LCBR collaborates on a wide variety of clinical studies, clinical trials, and epidemiology studies on local, national, and international scales. Our research portfolio includes molecular and genetic Epidemiology family-based genetic research, clinical trials and basic studies using murine models of disease.

Examples include epidemiological studies such as the National Heart, Lung, and Blood Institute's (NHLBI) Multi-Ethnic Study of Atherosclerosis (MESA) and Cardiovascular Health Study (CHS). The LCBR is the central analysis lab on these studies as well as the main sample repository. 

Technical Information

Biorepository

Body

The LCBR currently houses a family of individual repositories of approximately 4 million samples, each with specifically labeled and databased sample sets from:

Cohort Studies:

  • Participants are followed over time
  • Samples collected: blood based, saliva, tissue, urine, hair, fingernails, microbiome

Clinical Trials

Assay Lab

Body

Hospital Based Assays:

  • HbA1c, glucose, and metabolic panels
  • Data is reportable to participants

Research Based Assays:

  • Basic ELISA
  • Multiplexed Assays
  • Targeted Proteomics
  • Neurology Panels
  • Immune Cell Phenotyping
  • Extracelluar Vesicle Phenotyping