Steven Roberts, PhD

BIO

• 2003-2008: PhD: Biochemistry and Biophysics, University of North Carolina-Chapel Hill. Studied the activities of the DNA end recognition protein, Ku, during non-homologous end joining of chromosome breaks under the direction of Dr. Dale Ramsden.
• 2009-2014: Post-doctoral training: National Institute of Environmental Health Sciences. Studied the genome-wide distribution of damage-induced mutations in yeast and human cancers, identifying mechanisms resulting in simultaneous, closely spaced mutation clusters under the mentorship of Dr. Dmitry Gordenin.
• 2014-2023: Assistant/Associate Professor: Washington State University. Determined a causative role for APOBEC3A in cancer mutagenesis, determined these enzymes mutated cancer genomes by deaminating replication intermediates, and identified the importance of atypical UV photoproducts in causing driver mutations in melanoma.
• 2023-present: Associate Professor: University of Vermont. Continued studies on APOBECs, UV mutagenesis, transcription-associated mutagenesis, and oxidation-induced mutagenesis.

Courses

MMG 6330 Advanced Genetics and Genomics

Publications

Steve' Robert's publications

Area(s) of expertise

• Genome dynamics: mechanisms of mutation and chromosome alteration that contribute to human disease.
• Roles of APOBEC cytidine deaminases in cancer mutagenesis
• Genome-wide mapping of DNA lesions
• DNA damage-induced mutation
• Mutagenic DNA double-strand break repair