Michael Godsey
Associate Professor, Biochemistry
Director, Master of Medical Science Program
PRONOUNS he/him
- Ph.D., Oregon Health & Science University
- M.S., University of Oregon
- Postdoctoral Training, University of Illinois in Chicago
Department of Biochemistry
BIO
Michael Godsey, Ph.D., is an Associate Professor of Biochemistry and the Director of the Master of Medical Science program. His research interest is in the area of structural biology, having trained in multiple methods of protein structure solution. His research experience spans structural studies on a variety of systems, including ion-gated channels, multidrug resistance regulators, and activators of cancer prodrugs, having worked in labs at the University of Oregon, Oregon Health & Science University, Northwestern University, and Yale University.
A member of the Teaching Academy, Dr. Godsey is also an experienced and enthusiastic educator, having taught science and biochemistry at levels from junior high through medical school. He is the course director for several biochemistry courses, with decades of experience in building and delivering both online and on-campus education at the university level.
Courses
- BIOC 3001 (online)
- BIOC 6001 (online and on-campus)
- BIOC 6002 (online and on-campus)
Publications
Bio
Michael Godsey, Ph.D., is an Associate Professor of Biochemistry and the Director of the Master of Medical Science program. His research interest is in the area of structural biology, having trained in multiple methods of protein structure solution. His research experience spans structural studies on a variety of systems, including ion-gated channels, multidrug resistance regulators, and activators of cancer prodrugs, having worked in labs at the University of Oregon, Oregon Health & Science University, Northwestern University, and Yale University.
A member of the Teaching Academy, Dr. Godsey is also an experienced and enthusiastic educator, having taught science and biochemistry at levels from junior high through medical school. He is the course director for several biochemistry courses, with decades of experience in building and delivering both online and on-campus education at the university level.
Courses
- BIOC 3001 (online)
- BIOC 6001 (online and on-campus)
- BIOC 6002 (online and on-campus)
Publications
Select Publications
- Oken AC, Krishnamurthy I, Savage JC, Lisi NE, Godsey MH, Mansoor SE. Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology. Front Pharmacol. 2022 Jun 17;13:925880. doi: 10.3389/fphar.2022.925880. PMID: 35784697; PMCID: PMC9248971.
- Oken AC, Ditter IA, Lisi NE, Krishnamurthy I, Godsey MH, Mansoor SE. P2X<sub>7</sub> receptors exhibit at least three modes of allosteric antagonism. Sci Adv. 2024 Oct 4;10(40):eado5084. doi: 10.1126/sciadv.ado5084. Epub 2024 Oct 4. PMID: 39365862; PMCID: PMC11451537.
- Oken AC, Lisi NE, Krishnamurthy I, McCarthy AE, Godsey MH, Glasfeld A, Mansoor SE. High-affinity agonism at the P2X<sub>7</sub> receptor is mediated by three residues outside the orthosteric pocket. Nat Commun. 2024 Aug 6;15(1):6662. doi: 10.1038/s41467-024-50771-6. PMID: 39107314; PMCID: PMC11303814.
- Godsey MH, Davulcu O, Nix JC, Skalicky JJ, Brüschweiler RP, Chapman MS. The Sampling of Conformational Dynamics in Ambient-Temperature Crystal Structures of Arginine Kinase. Structure. 2016 Oct 4;24(10):1658-1667. doi: 10.1016/j.str.2016.07.013. Epub 2016 Sep 1. PMID: 27594681; PMCID: PMC5052116.
- Godsey MH, Ort S, Sabini E, Konrad M, Lavie A. Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization. Biochemistry. 2006 Jan 17;45(2):452-61. doi: 10.1021/bi0518646. PMID: 16401075.