John DeWitt
Associate Professor
Medical Director- Neuropathology
Medical Director- Autopsy
111 Colchester Ave
MP1-109
Burlington, VT 05405
United States
- Clinical fellow, Harvard University, Massachusetts General Hospital, Boston, MA
- Research fellow, Harvard University, Massachusetts General Hospital, Boston, MA
- Fellowship in Neuropathology. Harvard University, Massachusetts General Hospital, Boston, MA
- Residency in Anatomic Pathology. Harvard University, Massachusetts General Hospital, Boston, MA
- M.D., University of Vermont College of Medicine, Burlington, VT
- Ph.D., Neuroscience, University of Vermont, Burlington, VT
- M.S., Neuroscience, Brandeis University, Waltham MA
- B.S. Neuroscience, Brandeis University, Waltham, MA
Department of Pathology and Laboratory Medicine
University of Vermont Cancer Center
Areas of expertise
Neuropathology, Autopsy
BIO
John DeWitt, M.D., Ph.D., is an Associate Professor on the Clinical Scholar track in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. He serves as Attending Pathologist for Neuropathology and Autopsy Services at the University of Vermont Medical Center, where he is the Section Medical Director of the Autopsy Service, Subspecialty Director of Neuropathology, and Medical Director of the UVMMC Biobank. Dr. DeWitt is board certified in Anatomic Pathology and Neuropathology and is the only practicing neuropathologist in the state of Vermont. His clinical and scholarly work centers on neurodegenerative disease, brain tumors, and diagnostic neuropathology, complemented by leadership roles within institutional committees—including the Protocol Review and Monitoring Committee—and national service within the American Association of Neuropathologists. As an educator, Dr. DeWitt is actively engaged in teaching across undergraduate, medical student, and residency levels, serving as the educational lead for neuropathology at UVM.
Nationally recognized for his contributions to neuropathology, Dr. DeWitt has developed a strong scholarly profile centered on brain tumors, neurodegenerative disease, and diagnostic neuropathology. His research output includes 22 peer reviewed publications spanning high impact work in medulloblastoma and glioblastoma genomics, neurodegenerative disease, and neuropathologic case studies, along with multiple book chapters and online educational publications that serve an international audience. He has contributed to collaborative, field advancing research, including studies published in Nature and Cell on the molecular architecture of medulloblastoma and glioblastoma during his postdoctoral training at Massachusetts General Hospital and Harvard Medical School. His national service includes roles within the American Association of Neuropathologists—as Membership Committee Chair, Constitution Committee member, and platform moderator—and peer reviewer responsibilities for leading journals such as JNEN, Acta Neuropathologica Communications, and Alzheimer’s & Dementia. A dedicated educator, Dr. DeWitt has been repeatedly recognized for excellence in teaching, including nominations in 2020 and 2024 and recipient of the Pathology Residency Teaching Award in 2023. He has also developed innovative neuropathology curricula, including interactive PowerPoint modules and annually updated eModules that are now core components of the medical neuroscience course at UVM. In addition to these contributions, he has mentored numerous medical students, residents, and faculty across multiple programs, supporting their professional development and scholarly growth.
As Associate Professor and the only practicing neuropathologist in Vermont, Dr. DeWitt is committed to advancing high quality patient care, expanding access to subspecialty neuropathology services, and strengthening the integration of neuropathologic expertise across the region. Building on his leadership roles in the Autopsy Service, Neuropathology, and the UVMMC Biobank, he is actively engaged in initiatives to modernize diagnostic workflows, including efforts to bring rapid molecular testing for brain tumors in house and to evaluate the impact of these innovations on patient outcomes. He continues to advance neurodegenerative disease research through collaborations within Vermont and New England, leveraging the institutional brain and tumor banks he directs to support multidisciplinary investigation. His ongoing priorities include expanding autopsy-based research, enhancing tissue-based resources for investigators, and strengthening regional and national collaborations in neuropathology. As an educator, Dr. DeWitt remains dedicated to developing innovative curricula and mentoring learners at all levels to ensure the next generation of physicians and scientists are prepared to advance the field.
Publications
Bio
John DeWitt, M.D., Ph.D., is an Associate Professor on the Clinical Scholar track in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. He serves as Attending Pathologist for Neuropathology and Autopsy Services at the University of Vermont Medical Center, where he is the Section Medical Director of the Autopsy Service, Subspecialty Director of Neuropathology, and Medical Director of the UVMMC Biobank. Dr. DeWitt is board certified in Anatomic Pathology and Neuropathology and is the only practicing neuropathologist in the state of Vermont. His clinical and scholarly work centers on neurodegenerative disease, brain tumors, and diagnostic neuropathology, complemented by leadership roles within institutional committees—including the Protocol Review and Monitoring Committee—and national service within the American Association of Neuropathologists. As an educator, Dr. DeWitt is actively engaged in teaching across undergraduate, medical student, and residency levels, serving as the educational lead for neuropathology at UVM.
Nationally recognized for his contributions to neuropathology, Dr. DeWitt has developed a strong scholarly profile centered on brain tumors, neurodegenerative disease, and diagnostic neuropathology. His research output includes 22 peer reviewed publications spanning high impact work in medulloblastoma and glioblastoma genomics, neurodegenerative disease, and neuropathologic case studies, along with multiple book chapters and online educational publications that serve an international audience. He has contributed to collaborative, field advancing research, including studies published in Nature and Cell on the molecular architecture of medulloblastoma and glioblastoma during his postdoctoral training at Massachusetts General Hospital and Harvard Medical School. His national service includes roles within the American Association of Neuropathologists—as Membership Committee Chair, Constitution Committee member, and platform moderator—and peer reviewer responsibilities for leading journals such as JNEN, Acta Neuropathologica Communications, and Alzheimer’s & Dementia. A dedicated educator, Dr. DeWitt has been repeatedly recognized for excellence in teaching, including nominations in 2020 and 2024 and recipient of the Pathology Residency Teaching Award in 2023. He has also developed innovative neuropathology curricula, including interactive PowerPoint modules and annually updated eModules that are now core components of the medical neuroscience course at UVM. In addition to these contributions, he has mentored numerous medical students, residents, and faculty across multiple programs, supporting their professional development and scholarly growth.
As Associate Professor and the only practicing neuropathologist in Vermont, Dr. DeWitt is committed to advancing high quality patient care, expanding access to subspecialty neuropathology services, and strengthening the integration of neuropathologic expertise across the region. Building on his leadership roles in the Autopsy Service, Neuropathology, and the UVMMC Biobank, he is actively engaged in initiatives to modernize diagnostic workflows, including efforts to bring rapid molecular testing for brain tumors in house and to evaluate the impact of these innovations on patient outcomes. He continues to advance neurodegenerative disease research through collaborations within Vermont and New England, leveraging the institutional brain and tumor banks he directs to support multidisciplinary investigation. His ongoing priorities include expanding autopsy-based research, enhancing tissue-based resources for investigators, and strengthening regional and national collaborations in neuropathology. As an educator, Dr. DeWitt remains dedicated to developing innovative curricula and mentoring learners at all levels to ensure the next generation of physicians and scientists are prepared to advance the field.