Larner College of Medicine

David Schneider

Professor of Medicine

Medical Director, Cardiovascular Medicine

Director, Cardiovascular Research Institute of Vermont

man smiling
Alma mater(s)
  • M.D., Medicine, University of Cincinnati
  • B.A., Philosophy, University of Notre Dame

Areas of expertise

  • Cardiovascular Disease
  • Thrombosis
  • Platelet function

BIO

Dr. David Schneider is a cardiologist and Director of Cardiovascular Services at the University of Vermont Health Network in Burlington, VT. He is also a professor at the UVM Larner College of Medicine. Dr. Schneider specializes in heart and vascular conditions such as heart attacks, heart valve disease, and treatment of hypertension and hyperlipidemia, which is an abnormally high concentration of fats in the blood.

His primary research focus is thrombosis. He has pursued basic and translational studies involving the fibrinolytic system, the coagulation cascade, and platelet function. A common theme to this work has been to identify patients who are pro-thrombotic and thereby at increased risk of cardiovascular events. Research designed to elucidate mechanisms contributing to increased platelet reactivity identified platelet expression of FcɣRIIa. This surface protein amplifies platelet reactivity and led to studies demonstrating that greater expression is associated with a greater risk of cardiovascular events. The prognostic value of this test has been demonstrated in both a single center trial and an 800 patient 25 center study that identified this marker as a novel biomarker of high and low risk of subsequent events after a myocardial infarction.


Dr. Schneider's Patents

United States Patent number 6,391,568 (Method for Determining Platelet reactivity in a Whole Blood Sample)

United States Patent number 6,770,660 (Method for Inhibiting Platelet Aggregation)

United States Patent number 8,680,052 B1 (Methods of Treating, Reducing the Incidence of, and/or Preventing Ischemic Events

United States Patent number 10,502,737 (Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection)

United States Patent number: US 11,747,335 B2 (divisional patent to Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection

United States Patent number: US 12,253,520 (continuation patent to Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection

Australian Patent number 2019255622 (Compositions and methods for treating cardiovascular disease in selected patients)

 

Dr. Schneider's professional associations

2008 - 2012 Councilor, Society of Experimental Biology

2005 - 2018 Associate Editor, Coronary Artery Disease Journal

2005 - 2010 Reviewer, NIH Special Emphasis Panels

2003 - Editorial Board, American Journal of Cardiology

2000 - 2004 Reviewer, AHA Northeast Section

2000 - 2005 Steering Committee, BARI 2D Study

1997 - Fellow, American Heart Association

1995 - Fellow, American College of Cardiology

 

Dr. Schneider's postdoctoral training

Fellow in Cardiovascular Disease, Washington University

Chief Medical Resident, University of Colorado Health Sciences Center

Intern and Resident in Medicine, University of Colorado Health Sciences Center

Publications

Dr. Schneider's publications

Awards and Achievements

2013 Outstanding Research Mentor, University of Vermont

2005 Who’s Who Among American Teachers , Who's Who

2004 Who’s Who Among American Teachers , Who's Who

1986 Merrell Dow Pharmacology Award, University of Cincinnati

1986 Outstanding Student in Internal Medicine, University of Cincinnati

1985 Alpha Omega Alpha, University of Cincinnati

1982 Alpha Epsilon Delta , University of Notre Dame

1982 Magna Cum Laude, University of Notre Dame

Bio

Dr. David Schneider is a cardiologist and Director of Cardiovascular Services at the University of Vermont Health Network in Burlington, VT. He is also a professor at the UVM Larner College of Medicine. Dr. Schneider specializes in heart and vascular conditions such as heart attacks, heart valve disease, and treatment of hypertension and hyperlipidemia, which is an abnormally high concentration of fats in the blood.

His primary research focus is thrombosis. He has pursued basic and translational studies involving the fibrinolytic system, the coagulation cascade, and platelet function. A common theme to this work has been to identify patients who are pro-thrombotic and thereby at increased risk of cardiovascular events. Research designed to elucidate mechanisms contributing to increased platelet reactivity identified platelet expression of FcɣRIIa. This surface protein amplifies platelet reactivity and led to studies demonstrating that greater expression is associated with a greater risk of cardiovascular events. The prognostic value of this test has been demonstrated in both a single center trial and an 800 patient 25 center study that identified this marker as a novel biomarker of high and low risk of subsequent events after a myocardial infarction.


Dr. Schneider's Patents

United States Patent number 6,391,568 (Method for Determining Platelet reactivity in a Whole Blood Sample)

United States Patent number 6,770,660 (Method for Inhibiting Platelet Aggregation)

United States Patent number 8,680,052 B1 (Methods of Treating, Reducing the Incidence of, and/or Preventing Ischemic Events

United States Patent number 10,502,737 (Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection)

United States Patent number: US 11,747,335 B2 (divisional patent to Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection

United States Patent number: US 12,253,520 (continuation patent to Antithrombotic Compositions and Methods for Assaying Platelet Reactivity and Treatment Selection

Australian Patent number 2019255622 (Compositions and methods for treating cardiovascular disease in selected patients)

 

Dr. Schneider's professional associations

2008 - 2012 Councilor, Society of Experimental Biology

2005 - 2018 Associate Editor, Coronary Artery Disease Journal

2005 - 2010 Reviewer, NIH Special Emphasis Panels

2003 - Editorial Board, American Journal of Cardiology

2000 - 2004 Reviewer, AHA Northeast Section

2000 - 2005 Steering Committee, BARI 2D Study

1997 - Fellow, American Heart Association

1995 - Fellow, American College of Cardiology

 

Dr. Schneider's postdoctoral training

Fellow in Cardiovascular Disease, Washington University

Chief Medical Resident, University of Colorado Health Sciences Center

Intern and Resident in Medicine, University of Colorado Health Sciences Center

Awards and Achievements

2013 Outstanding Research Mentor, University of Vermont

2005 Who’s Who Among American Teachers , Who's Who

2004 Who’s Who Among American Teachers , Who's Who

1986 Merrell Dow Pharmacology Award, University of Cincinnati

1986 Outstanding Student in Internal Medicine, University of Cincinnati

1985 Alpha Omega Alpha, University of Cincinnati

1982 Alpha Epsilon Delta , University of Notre Dame

1982 Magna Cum Laude, University of Notre Dame