Larner College of Medicine

Chris E. Holmes

Professor of Medicine, Hematology and Oncology

Director, Cancer Clinical Programs, UVM Cancer Center

Division Chief for Hematology and Oncology

A person wearing a green blazer and a white shirt
Alma mater(s)
  • M.D., University of Virginia School of Medicine
  • Ph.D., Chemistry, University of Virginia Graduate School of Arts and Sciences
  • B.S., magna cum laude, Honors Scholar, Chemistry, James Madison University
  • Internship, Internal Medicine, Robert Larner College of Medicine
  • Residency, Internal Medicine, Robert Larner College of Medicine
  • Fellowship, Hematology, University of Vermont Medical Center
Affiliated Department(s)

Department of Medicine

Division of Hematology and Oncology

UVM Cancer Center

Areas of expertise

thrombosis, bleeding, cancer-associated thrombosis, platelets, clinical research, translational research.

BIO

Chris E. Holmes MD, PhD, is a Professor of Medicine with tenure at the Larner College of Medicine, Department of Medicine. She currently serves as Division Chief for Hematology and Oncology as well as Director of Cancer Clinical Programs at the UVM Cancer Center. Her clinical expertise is in the field of classical hematology and her research focuses on the prevention of thrombosis and bleeding in patients with cancer. As Director of the Vermont Regional Bleeding Disorder Center, she leads the only Nationally Designated Hemophilia Treatment Center in Vermont.

Publications

Google Scholar Publications

Awards and Achievements

  • Member, Board of Directors, Cardiovascular Research Institute, 
  • University of Vermont, College of Medicine Fellow, 
  • American College of Physicians Executive Committee, 
  • New England Region 1, Hemophilia Treatment Centers Co-chair, 
  • Research Subcommittee, New England Region 1 
  • Hemophilia Treatment Centers Inventor Award, 
  • University of Vermont Quality Scholarship Award, Department of Medicine

Bio

Chris E. Holmes MD, PhD, is a Professor of Medicine with tenure at the Larner College of Medicine, Department of Medicine. She currently serves as Division Chief for Hematology and Oncology as well as Director of Cancer Clinical Programs at the UVM Cancer Center. Her clinical expertise is in the field of classical hematology and her research focuses on the prevention of thrombosis and bleeding in patients with cancer. As Director of the Vermont Regional Bleeding Disorder Center, she leads the only Nationally Designated Hemophilia Treatment Center in Vermont.

Awards and Achievements

  • Member, Board of Directors, Cardiovascular Research Institute, 
  • University of Vermont, College of Medicine Fellow, 
  • American College of Physicians Executive Committee, 
  • New England Region 1, Hemophilia Treatment Centers Co-chair, 
  • Research Subcommittee, New England Region 1 
  • Hemophilia Treatment Centers Inventor Award, 
  • University of Vermont Quality Scholarship Award, Department of Medicine

Select Publications

  • Impact of Venous Thrombosis Prevention in Ambulatory Oncology: Importance of Guideline Adherence. JCO Oncol Pract 2026: https://doi.org/10.1200/OP-25-01211 
  • Direct Oral Anticoagulants vs Low-Molecular-Weight Heparin and Recurrent VTE in Patients with Cancer: A Randomized Clinical Trial JAMA. 2023;329(22):1924-1933. doi:10.1001/jama.2023.7843 
  • A Successful Model for Guideline Implementation to Prevent Cancer-Associated Thrombosis: Venous Thromboembolism Prevention in the Ambulatory Cancer Clinic JCO Oncol Pract 2020 April 8. doi: 10.1200/JOP.19.00697. PMID: 32267798 
  • Venous thromboembolism prevention program implementation in a community oncology practice: a cohort study. Lancet Reg Health Am 2024 38: 100866. DOI 10.1016/j.lana.2024.100866. 
  • The platelet contribution to cancer progression. J Thromb Haemostasis 2011; 9(2):237-249. PMID: 21040448.