Falls Laboratory of Behavioral Neuroscience
Research in the Falls Laboratory examines the neurobiological mechanism involved in both the elicitation and reduction of fear and anxiety. We accomplish this using a variety of techniques including behavioral assessment of fear and anxiety, pharmacological manipulations, and neuroanatomical and molecular techniques. Specific questions include:
- What are the neurobiological mechanisms underlying the interaction of fear and anxiety and stress?
- What are the neurobiological mechanisms of the anxiolytic effects of voluntary exercise?
- How does stress interact with the anxiolytic effect of exercise?
William A. Falls, Ph.D.Professor and Chair of Psychological Science
Brendan Hare, M.A.
Stephanie Menotti, B.A.
- Lezak, K. M., Roman, C.W. Braas, K.M., Schutz, K.C., Schulkin, J., Falls, W.A., May, V, & Hammack, S.E * (in press) Regulation of bed nucleus of the stria terminalis PACAP expression by stress and corticosterone. Journal of Molecular Neuroscience.
- Hare, B.H., Beierle, J.A. Toufexis, D. Toufexis, D.J., Hammack, S.E. & Falls, W.A.* (2014). Exercise associated changes in the corticosterone response to acute restraint stress: evidence for increased adrenal sensitivity and reduced corticosterone response duration. Neuropsychopharmacology. 39, 1262-1269 doi:10.1038/npp.2013.329.
- Hare, B.H., D’Onfro, K.D., Hammack, S.E. & Falls, W.A. *(2012). Prior Stress Interferes With the Anxiolytic Effect of Exercise in C57BL/6J Mice. Behavioral Neuroscience. 126, 850-856.
- Sibold, J.S.*, Hammack, S.E. & Falls, W.A. (2011). C57 mice increase wheel-running behavior following stress: preliminary findings. Perceptual and Motor Skills. 113, 605-618.
- Falls, W.A.* MacAulay, C.M. & Fox, J.H. (2010). Voluntary exercise improves both learning and consolidation of cued conditioned fear in C57 mice. Behavioural Brain Research. 207, 321-331.
The Falls Lab benefits from collaborations with several UVM faculty including:
- Falls Laboratory of Behavioral Neuroscience
- Green Laboratory
- Hammack Laboratory of Behavioral Neuroscience
- Center for Research on Emotion, Stress, and Technology (CREST)
- Person Environment Zone (PEZ) Projects
- Seasonal Affective Disorder (SAD)
- Sexual Health Research Clinic