Nimrat Chatterjee, PhD
Assistant Professor
Genome Instability Mechanisms in Cancer and Host-Virus Interactions
PRONOUNS she/her/hers
nimrat.chatterjee@med.uvm.edu
FMRB 350
149 Beaumont Ave
University of Vermont
Burlington, VT 05405
United States
Pronouns
she/her/hers
Affiliated Department(s)
- Dept of Microbiology and Molecular Genetics
- University of Vermont Cancer Center
BIO
- 2014 - PhD - Baylor College of Medicine, Advisor - Dr. John Wilson, Dissertation title: Environmental stress induces trinucleotide repeat instability.
- 2015 - Postdoc Training 1 - Mentor - Dr. Alison Bertuch - Projects - DNA repair, bone marrow failure disorders
- 2020 - Postdoc Training 2 - Mentor - Dr. Graham C. Walker - Projects - Therapeutic targeting & biochemical mutagenic pathways
- 2018 - Massachusetts Institute of Technology - Kauffman Teaching Certification
- 2022 - Ragon Institute of MIT/Harvard/MGH - BSL3 training - Mentor - Dr. Mike Young - Projects - SARCS CoV-2 infection experiments
Courses
- MMG 3990/5270 - Cancer Genetics
- MMG 3330 - Genetics and Genomics
- BIOC 6072 - Cancer Biology
- PATH 6071 - Molecular Pathology
Publications
Nimrat Chatterjee's publications
Area(s) of expertise
The lab examines some critical questions on cancer resistance:
- What factors drive cancer onset?
- How cancer cells divide unabated and relapse after initial treatment.
- How can therapeutic targeting rescue cancer resistance?
- We specifically investigate one translesion synthesis protein, REV1, that might help address missing links in understanding cancer etiology. We are also examining how stress factors might influence REV1’s functionality in cancer sustenance and therapy resistance.
- Expertise in tissue culturing, DNA damage, cytotoxicity assays, infections, pPCR/PCR, western blotting, microscopy, and other molecular biology methods.
Bio
- 2014 - PhD - Baylor College of Medicine, Advisor - Dr. John Wilson, Dissertation title: Environmental stress induces trinucleotide repeat instability.
- 2015 - Postdoc Training 1 - Mentor - Dr. Alison Bertuch - Projects - DNA repair, bone marrow failure disorders
- 2020 - Postdoc Training 2 - Mentor - Dr. Graham C. Walker - Projects - Therapeutic targeting & biochemical mutagenic pathways
- 2018 - Massachusetts Institute of Technology - Kauffman Teaching Certification
- 2022 - Ragon Institute of MIT/Harvard/MGH - BSL3 training - Mentor - Dr. Mike Young - Projects - SARCS CoV-2 infection experiments
Courses
- MMG 3990/5270 - Cancer Genetics
- MMG 3330 - Genetics and Genomics
- BIOC 6072 - Cancer Biology
- PATH 6071 - Molecular Pathology
Publications
Areas of Expertise
The lab examines some critical questions on cancer resistance:
- What factors drive cancer onset?
- How cancer cells divide unabated and relapse after initial treatment.
- How can therapeutic targeting rescue cancer resistance?
- We specifically investigate one translesion synthesis protein, REV1, that might help address missing links in understanding cancer etiology. We are also examining how stress factors might influence REV1’s functionality in cancer sustenance and therapy resistance.
- Expertise in tissue culturing, DNA damage, cytotoxicity assays, infections, pPCR/PCR, western blotting, microscopy, and other molecular biology methods.
Our Lab Focus
We are very interested in understanding mechanisms that maintain genomic stability and how dysfunction in these processes results in human diseases such as cancer, infectious diseases, and neurodegenerative disorders.