The study, “History of adverse pregnancy outcomes in women with pulmonary arterial hypertension: a single-center pilot study,” by Jessica Badlam, M.D., assistant professor of medicine, Renee Stapleton, M.D., Ph.D., professor of medicine, Peter Callas, Ph.D., associate professor of medicine, Ira Bernstein, M.D., professor of obstetrics, gynecology, and reproductive sciences, and a colleague from Vanderbilt University School of Medicine, was published in Pulmonary Circulation.
“An unexplored and potentially promising link that may prove useful in earlier detection and risk stratification of vascular disease in females is that between preeclampsia and PAH,” the authors wrote. “Given that not all patients with a risk factor develop PAH, such as connective tissue disease or congenital heart disease, APOs may be a second ‘hit’ or perhaps another vascular manifestation of the underlying disease.”