Martin Chang
Professor
Director of Clinical Research
Director of Clinical Informatics- Anatomic Pathology
- M.D., University of Toronto
- Ph.D., Physiology, University of Toronto
- Hon.B.Sc., University of Toronto
Department of Pathology and Laboratory Medicine
University of Vermont Cancer Center
Areas of expertise
Surgical Pathology, Breast and Gynecological tract
BIO
Martin C. Chang, M.D., Ph.D., is a Professor in the Clinical Scholar Pathway and serves as Director for Clinical Research and Director of Clinical Informatics (Anatomic Pathology) in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. He is also an Attending Pathologist and Consultant in Breast and Gynecologic Pathology at the University of Vermont Medical Center. Dr. Chang is certified in Anatomic and Clinical Pathology by the American Board of Pathology and holds additional certification in Anatomical Pathology through the Royal College of Physicians and Surgeons of Canada. His prior leadership positions include Section Head of Surgical Pathology, Director of the Breast Pathology Service, Director of the Circulating Tumor Cell Program at Sinai Health System/University of Toronto; Surgical Pathology Fellowship Director and Vice Chair for Faculty Affairs in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. His areas of clinical specialization include breast and gynecologic pathology, while his research and educational focus includes cancer biomarkers, translational breast cancer research, and pathology informatics.
Nationally and internationally recognized for his contributions to breast pathology, biomarker validation, and translational breast cancer research, Dr. Chang has served on committees for organizations including Cancer Care Ontario, the Canadian Clinical Trials Group, and multiple NIH‑funded collaborative research teams. He has published extensively, with 65 peer‑reviewed publications, five book chapters, and more than 70 scientific abstracts. He has been a lead pathologist for major multicenter clinical trials such as the Canadian Clinical Trials Group MA.32 metformin trial and has contributed to provincial and national guideline development for breast cancer biomarker testing. Dr. Chang has received institutional research funding as Co‑PI on NIH R03‑supported work and departmental grants, and he holds a strong record of mentorship of residents, fellows, and junior faculty. He is an active educator and curriculum developer.
As an academic anatomic pathologist, Director of Clinical Research, and Director for Clinical Informatics in Pathology and Laboratory Medicine, Dr. Chang is committed to advancing evidence‑based practice, enhancing research productivity, and fostering faculty development across the department. His initiatives focus on expanding clinical and translational breast cancer research, particularly in data-driven diagnostics; and mitochondrial biology and tumor metabolism, in collaboration with the UVM Redox Biology Unit. He is also leading strategic efforts to integrate pathology informatics innovations to anatomic pathology practice. These efforts include the application of digital-pathology and data‑science approaches to optimize departmental efficiency and patient care.
Publications
Bio
Martin C. Chang, M.D., Ph.D., is a Professor in the Clinical Scholar Pathway and serves as Director for Clinical Research and Director of Clinical Informatics (Anatomic Pathology) in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. He is also an Attending Pathologist and Consultant in Breast and Gynecologic Pathology at the University of Vermont Medical Center. Dr. Chang is certified in Anatomic and Clinical Pathology by the American Board of Pathology and holds additional certification in Anatomical Pathology through the Royal College of Physicians and Surgeons of Canada. His prior leadership positions include Section Head of Surgical Pathology, Director of the Breast Pathology Service, Director of the Circulating Tumor Cell Program at Sinai Health System/University of Toronto; Surgical Pathology Fellowship Director and Vice Chair for Faculty Affairs in the Department of Pathology and Laboratory Medicine at the Larner College of Medicine at the University of Vermont. His areas of clinical specialization include breast and gynecologic pathology, while his research and educational focus includes cancer biomarkers, translational breast cancer research, and pathology informatics.
Nationally and internationally recognized for his contributions to breast pathology, biomarker validation, and translational breast cancer research, Dr. Chang has served on committees for organizations including Cancer Care Ontario, the Canadian Clinical Trials Group, and multiple NIH‑funded collaborative research teams. He has published extensively, with 65 peer‑reviewed publications, five book chapters, and more than 70 scientific abstracts. He has been a lead pathologist for major multicenter clinical trials such as the Canadian Clinical Trials Group MA.32 metformin trial and has contributed to provincial and national guideline development for breast cancer biomarker testing. Dr. Chang has received institutional research funding as Co‑PI on NIH R03‑supported work and departmental grants, and he holds a strong record of mentorship of residents, fellows, and junior faculty. He is an active educator and curriculum developer.
As an academic anatomic pathologist, Director of Clinical Research, and Director for Clinical Informatics in Pathology and Laboratory Medicine, Dr. Chang is committed to advancing evidence‑based practice, enhancing research productivity, and fostering faculty development across the department. His initiatives focus on expanding clinical and translational breast cancer research, particularly in data-driven diagnostics; and mitochondrial biology and tumor metabolism, in collaboration with the UVM Redox Biology Unit. He is also leading strategic efforts to integrate pathology informatics innovations to anatomic pathology practice. These efforts include the application of digital-pathology and data‑science approaches to optimize departmental efficiency and patient care.