Marc S. Greenblatt, M.D.

Professor of Medicine, Division Hematology and Oncology

Co-Director, Cancer Genetics and Prevention Program, University of Vermont Cancer Center

Medical Oncologist, UVM Health Network

A person wearing a light tan plaid shirt
Alma mater(s)
  • B.S., Pennsylvania State University
  • M.D., Sidney Kimmel Medical College at Thomas Jefferson University
Affiliated Department(s)

Department of Medicine, Division of Hematology and Oncology

University of Vermont Cancer Center

Dr. Greenblatt's UVM Health Network provider page

Dr. Greenblatt's UVM Cancer Center member page

Area(s) of expertise

Clinical Specialty:  

  • Gastrointestinal Cancer
  • Cancer Genetics

Research Interests:  

  • Cancer Genetics
  • Classifying genetic variants in cancer susceptibility genes
  • Hereditary Colon Cancer and Polyposis Syndromes
  • Chair of the InSiGHT-ClinGen Polyposis-Colorectal Cancer Variant Curation Expert Panel, which is refining strategies to classify variants in the APC, MUTYH, SMAD4, BMPR1, STK11, POLD1, and POLE genes.
  • Refining methods to classify genetic variants through membership in the ClinGen Sequence Variant Interpretation (SVI) Working Group. The SVI is improving criteria for interpreting and integrating multiple lines of evidence (epidemiology, statistics, clinical phenotype, tumor pathology, gene evolution, protein structure, functional assays, computational algorithms).

 

BIO

Dr. Marc Greenblatt is a medical oncologist at the University of Vermont Medical Center and a professor of medicine at the Larner College of Medicine as well as Co-Director of the Cancer Genetics and Prevention Program. Dr. Greenblatt's research interests are in interpreting genetic variants in cancer susceptibility genes by using multiple lines of evidence (epidemiology, statistics, tumor pathology, evolution, structure, and function, computational algorithms). He has led projects that have integrated in vitro and in silico (computational) data to interpret genetic variation. Dr. Greenblatt’s current research activities include general variant classification methods and interpretation of variants in hereditary polyposis and colorectal cancer genes.

Dr. Greenblatt's postdoctoral training

Research Fellowship, National Cancer Institute – Biotechnology Fellow, Laboratory of Human Carcinogenesis

Fellowship, University of New Mexico School of Medicine – Hematology-Oncology

Residency, University of New Mexico School of Medicine - Internal Medicine

Internship, University of New Mexico School of Medicine - Internal Medicine

Dr. Greenblatt maintains memberships in the following professional societies

American Association of Cancer Research

Alliance for Clinical Trials in Oncology

American Society of Human Genetics

American Society of Clinical Oncology

Collaborative Group of the Americas on Inherited GI Cancer (CGA-IGC)

Human Genome Organization

International Society for Gastrointestinal Hereditary Tumors (InSiGHT, Council Member))

 Vermont Medical Society

Courses

MED 2513: Outpatient Hematology/Oncology

Publications

Dr. Greenblatt's publications on Google Scholar

Bio

Dr. Marc Greenblatt is a medical oncologist at the University of Vermont Medical Center and a professor of medicine at the Larner College of Medicine as well as Co-Director of the Cancer Genetics and Prevention Program. Dr. Greenblatt's research interests are in interpreting genetic variants in cancer susceptibility genes by using multiple lines of evidence (epidemiology, statistics, tumor pathology, evolution, structure, and function, computational algorithms). He has led projects that have integrated in vitro and in silico (computational) data to interpret genetic variation. Dr. Greenblatt’s current research activities include general variant classification methods and interpretation of variants in hereditary polyposis and colorectal cancer genes.

Dr. Greenblatt's postdoctoral training

Research Fellowship, National Cancer Institute – Biotechnology Fellow, Laboratory of Human Carcinogenesis

Fellowship, University of New Mexico School of Medicine – Hematology-Oncology

Residency, University of New Mexico School of Medicine - Internal Medicine

Internship, University of New Mexico School of Medicine - Internal Medicine

Dr. Greenblatt maintains memberships in the following professional societies

American Association of Cancer Research

Alliance for Clinical Trials in Oncology

American Society of Human Genetics

American Society of Clinical Oncology

Collaborative Group of the Americas on Inherited GI Cancer (CGA-IGC)

Human Genome Organization

International Society for Gastrointestinal Hereditary Tumors (InSiGHT, Council Member))

 Vermont Medical Society

Courses

MED 2513: Outpatient Hematology/Oncology