Marc S. Greenblatt, M.D.
Professor of Medicine, Division Hematology and Oncology
Co-Director, Cancer Genetics and Prevention Program, University of Vermont Cancer Center
Medical Oncologist, UVM Health Network
89 Beaumont Ave
Given E217
Larner College of Medicine
Burlington, VT 05405
United States
- B.S., Pennsylvania State University
- M.D., Sidney Kimmel Medical College at Thomas Jefferson University
Department of Medicine, Division of Hematology and Oncology
University of Vermont Cancer Center
BIO
Dr. Marc Greenblatt is a medical oncologist at the University of Vermont Medical Center and a professor of medicine at the Larner College of Medicine as well as Co-Director of the Cancer Genetics and Prevention Program. Dr. Greenblatt's research interests are in interpreting genetic variants in cancer susceptibility genes by using multiple lines of evidence (epidemiology, statistics, tumor pathology, evolution, structure, and function, computational algorithms). He has led projects that have integrated in vitro and in silico (computational) data to interpret genetic variation. Dr. Greenblatt’s current research activities involve interpretation of variants in the DNA mismatch Repair genes that are responsible for Lynch syndrome, the most common form of hereditary colorectal cancer.
Dr. Greenblatt's postdoctoral training
Research Fellowship, National Cancer Institute - Biotechnology
Fellowship, National Cancer Institute - Cancer Biology
Fellowship, National Cancer Institute - Hematology Oncology
Residency, University of New Mexico School of Medicine - Hematology
Residency, University of New Mexico School of Medicine - Internal Medicine
Internship
University of New Mexico School of Medicine - Internal Medicine
Dr. Greenblatt maintains memberships in the following professional societies
Human Genome Variation Society, President 2012
American Association of Cancer Research
Alliance for Clinical Trials in Oncology
American Society of Human Genetics
American Society of Clinical Oncology
Collaborative Group of the Americas on Inherited Colorectal Cancer
Human Variome Project, Scientific Advisory Council
International Society for Gastrointestinal Hereditary Tumors (InSiGHT), Variant Interpretation Committee
Vermont Medical Society
Publications
Dr. Greenblatt's publications on Google Scholar
Area(s) of expertise
Cancer Genetics, Classifying genetic variants in cancer susceptibility genes, Hereditary Colon Cancer and Polyposis Syndromes
Hereditary Colorectal Cancer and Polyposis: Chair of the InSiGHT-ClinGen Polyposis-Colorectal Cancer Variant Curation Expert Panel, which is refining strategies to classify variants in the APC, MUTYH, SMAD4, BMPR1, STK11, POLD1, and POLE genes.
Refining methods to classify genetic variants through membership in the ClinGen Sequence Variant Interpretation (SVI) Working Group. The SVI is improving criteria for interpreting and integrating multiple lines of evidence (epidemiology, statistics, clinical phenotype, tumor pathology, gene evolution, protein structure, functional assays, computational algorithms).
Bio
Dr. Marc Greenblatt is a medical oncologist at the University of Vermont Medical Center and a professor of medicine at the Larner College of Medicine as well as Co-Director of the Cancer Genetics and Prevention Program. Dr. Greenblatt's research interests are in interpreting genetic variants in cancer susceptibility genes by using multiple lines of evidence (epidemiology, statistics, tumor pathology, evolution, structure, and function, computational algorithms). He has led projects that have integrated in vitro and in silico (computational) data to interpret genetic variation. Dr. Greenblatt’s current research activities involve interpretation of variants in the DNA mismatch Repair genes that are responsible for Lynch syndrome, the most common form of hereditary colorectal cancer.
Dr. Greenblatt's postdoctoral training
Research Fellowship, National Cancer Institute - Biotechnology
Fellowship, National Cancer Institute - Cancer Biology
Fellowship, National Cancer Institute - Hematology Oncology
Residency, University of New Mexico School of Medicine - Hematology
Residency, University of New Mexico School of Medicine - Internal Medicine
Internship
University of New Mexico School of Medicine - Internal Medicine
Dr. Greenblatt maintains memberships in the following professional societies
Human Genome Variation Society, President 2012
American Association of Cancer Research
Alliance for Clinical Trials in Oncology
American Society of Human Genetics
American Society of Clinical Oncology
Collaborative Group of the Americas on Inherited Colorectal Cancer
Human Variome Project, Scientific Advisory Council
International Society for Gastrointestinal Hereditary Tumors (InSiGHT), Variant Interpretation Committee
Vermont Medical Society
Publications
Areas of Expertise
Cancer Genetics, Classifying genetic variants in cancer susceptibility genes, Hereditary Colon Cancer and Polyposis Syndromes
Hereditary Colorectal Cancer and Polyposis: Chair of the InSiGHT-ClinGen Polyposis-Colorectal Cancer Variant Curation Expert Panel, which is refining strategies to classify variants in the APC, MUTYH, SMAD4, BMPR1, STK11, POLD1, and POLE genes.
Refining methods to classify genetic variants through membership in the ClinGen Sequence Variant Interpretation (SVI) Working Group. The SVI is improving criteria for interpreting and integrating multiple lines of evidence (epidemiology, statistics, clinical phenotype, tumor pathology, gene evolution, protein structure, functional assays, computational algorithms).