Interpreting Nuclear Medicine Studies

  • Most images are in gray scale and have poor anatomic detail, as seen in the image on the right.
  • Radioactive isotopes are injected or ingested, and the patient is scanned.
  • Photons hitting the detectors are counted and converted into images.
  • Black areas represent higher counts, indicating increased radiotracer uptake or "hot" spots.
  • White areas represent lower counts, indicating low uptake or "cold" spots.
  • In some studies, (such as PET scans) these images can be combined with standard CT scans to create a "fused" image.

Normal bone scan
Normal bone scan.

Intro to Bone Scans

  • Radiotracer- Technetium 99m MDP.
  • "Hot" uptake at sites of active turnover
    • Kidneys should be faintly visible. If there is sufficiently strong uptake in the bones, the kidneys will not be seen- this is called a superscan
  • Symmetry is your friend!
  • Focal uptake in the joints most likely represent degenerative changes.
  • If you are not sure- correlate

Normal bone scan with kidneys visible
Normal bone scan anterior (left) and posterior (right).