Musculoskeletal Imaging and Orthopaedic Biomechanics Laboratory

Improving musculoskeletal health through scientific investigations of structure and function


Dynamic Imaging of Joint Motion Using High-speed Dual Fluoroscopy


Imaging of Musculoskeletal Tissue Structure, Size and Composition


Joint Mechanics Estimation via Patient-Specific Computer Models


The overarching goal of the Musculoskeletal Imaging and Orthopaedic Biomechanics (MIOB) Laboratory is to improve human health and performance for those who suffer from musculoskeletal and orthopaedic conditions. Our approaches span experimental and computational methods. We use magnetic resonance imaging (MRI) to visualize disease and quantify anatomy, and we image bone motion directly with dynamic x-ray. Our computational studies combine patient-specific MR-based models with dynamic motion measurements to estimate internal tissue mechanics of orthopaedic tissues. Overall, the experimental and computational methods employed by the MIOB lab aim to improve health outcomes and reduce burdens imposed on patients and our healthcare system.

Lab News

Haley and Sadegh successfully defend their theses in back-to-back defenses. Congratulations you two!!  

Johnny delivers a podium presentation and a poster presentation at the North American Congress on Biomechanics in Ottawa, Canada. Well done Johnny!

Divya Pradip Roy and Sadegh Khodabandeloo join the MIOB Lab. Welcome Roy and Sadegh!

The Lab Director, Dr. Fiorentino, was awarded a NIH 21 grant entitled, "Biomechanical Markers of PTOA after ACL Reconstruction and Meniscal Resection."

Select Publications from MIOB Lab Members 

Ramsdell JC, Beynnon BB, Borah A, Gardner-Morse MG, Zhang J, Krug M, Tourville T, Geeslin M, Failla M, Vacek PM, Fiorentino NM. T1ρ and T2* Measurements in Small and Knee-Sized Magnetic Resonance Imaging Phantoms: Effect of Phantom Size and Position Relative to Isocenter. Osteoarthritis Imaging. 2023 Jul 11. 3:100162.

Ramsdell JC, Scott ME, Beynnon BD, Fiorentino NM. Does interpolation and intra-user variability affect the accuracy of arthrokinematic measurements in the knee? A dual fluoroscopic imaging and model-based tracking study. Med Eng Phys. 2023 Apr;114:103968. doi: 10.1016/j.medengphy.2023.103968. Epub 2023 Mar 14. PMID: 37030894

Schuring LL, Mozingo JD, Lenz AL, Uemura K, Atkins PR, Fiorentino NM, Aoki SK, Peters CL, Anderson AE. Acetabular labrum and cartilage contact mechanics during pivoting and walking tasks in individuals with cam femoroacetabular impingement syndrome. J Biomech. 2023 Jan;146:111424. doi: 10.1016/j.jbiomech.2022.111424. Epub 2022 Dec 24. PMID: 36603366

Pius AK, Beynnon BD, Fiorentino N, Gardner-Morse M, Vacek PM, DeSarno M, Failla M, Slauterbeck JR, Sturnick DR, Argentieri EC, Tourville TW. Articular cartilage thickness changes differ between males and females 4 years following anterior cruciate ligament reconstruction. J Orthop Res. 2021 Jul 20. doi: 10.1002/jor.25142. Online ahead of print.

Beynnon BD, Fiorentino NM, et al. Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma. J Orthop Res. 2020 Apr;38(4):759-767. doi: 10.1002/jor.24519. Epub 2019 Nov 19.

Atkins PR, Fiorentino NM, et al. In Vivo Pelvic and Hip Joint Kinematics in Patients With Cam Femoroacetabular Impingement Syndrome: A Dual Fluoroscopy Study. J Orthop Res. 2020 Apr;38(4):823-833. doi: 10.1002/jor.24509. Epub 2019 Nov 14.

Fiorentino NM, et al. Soft Tissue Artifact Causes Significant Errors in the Calculation of Joint Angles and Range of Motion at the Hip. Gait Posture. 2017 Jun;55:184-190. doi: 10.1016/j.gaitpost.2017.03.033. 

Lab Address

Stafford Hall
Room 411


Phone: +1 (802) 656 8082 

Dr. Fiorentino's Ofice

Votey Hall
Room 231B

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