Maggie Trout

Graduate Student

Advisor: James Stafford, Ph.D.

Maggie Trout
Alma mater(s)
  • University of Colorado Boulder

BIO

I am a Ph.D. student in James Stafford's lab in the department of neurological science. My research investigates potential roles of the mitochondria in pediatric brain cancer. Specifically, I am studying potential synergistic effects between inactivation of the mitochondrial antioxidant protein PRX3 and hyperactivation of the mitochondrial protease ClpP via ONC201 treatment in diffuse midline glioma (DMG). I am also investigating if mitochondrial can be transferred from non-cancerous cells in the brain to DMG cells and if that impacts their response to chemotherapy. The overall goal of this research is to identify new potential treatment options for this devastating disease.

Area(s) of expertise

Targeting the Mitochondria in Diffuse Midline Glioma treatment

Bio

I am a Ph.D. student in James Stafford's lab in the department of neurological science. My research investigates potential roles of the mitochondria in pediatric brain cancer. Specifically, I am studying potential synergistic effects between inactivation of the mitochondrial antioxidant protein PRX3 and hyperactivation of the mitochondrial protease ClpP via ONC201 treatment in diffuse midline glioma (DMG). I am also investigating if mitochondrial can be transferred from non-cancerous cells in the brain to DMG cells and if that impacts their response to chemotherapy. The overall goal of this research is to identify new potential treatment options for this devastating disease.

Areas of Expertise

Targeting the Mitochondria in Diffuse Midline Glioma treatment