The publications listed below
are organized by the three major areas of my research and scholarship:
1) Immunogenetics and Statistical Genetics, 2) Medical Biostatistics, 3) Education
and Program Evaluation.
Mack SJ, Gourraud PA, Single RM, Thomson G,
Hollenbach JA. Analytical methods for immunogenetic population data. Methods
Mol Biol. 2012;882:215-44.
Gourraud PA, Hollenbach JA, Barnetche T, Single RM,
Mack SJ. Standard methods for the management of immunogenetic data. Methods Mol
Biol. 2012;882:197-213.
Hollenbach JA, Nocedal I, Ladner MB, Single RM,
Trachtenberg EA. Killer cell immunoglobulin-like receptor (KIR) gene content
variation in the HGDP-CEPH populations. Immunogenetics. 2012. 64(10):719-37.
Vina MA, Hollenbach JA, Lyke KE, Sztein MB, Maiers
M, Klitz W, Cano P, Mack S, Single R, Brautbar C, Israel S, Raimondi E,
Khoriaty E, Inati A, Andreani M, Testi M, Moraes ME, Thomson G, Stastny P, Cao
K. Tracking human migrations by the analysis of the distribution of HLA
alleles, lineages and haplotypes in closed and open populations. Philos Trans R
Soc Lond B Biol Sci. 2012 Mar 19;367(1590):820-829.
Hollenbach, J. A., Mack, S. J., Gourraud, P.-A.,
Single, R. M., Maiers, M., Middleton, D., Thomson, G., Marsh, S. G. E., Varney,
M. D. and for the Immunogenomics Data Analysis Working Group (2011), A
community standard for immunogenomic data reporting and analysis: proposal for
a STrengthening the REporting of Immunogenomic Studies statement. Tissue
Antigens, 78: 333-344.
Hiby, S. E., Ashrafian-Bonab, M., Farrell, L.,
Single, R., Balloux, F., Carrington, M., Moffett, A. (2010). Distribution of
killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two
Iranian populations. Immunogenetics, 62(2), 65-73.
Thomson, G., Marthandan, N., Hollenbach, J. A.,
Mack, S. J., Erlich, H. A., Single, R., Waller, M. J., Marsh, S. G. E., Guidry,
P. A., Karp, D. R., Scheuermann, R. H., Thompson, S. D., Glass, D. N.,
Helmberg, W. (2010). Sequence Feature Variant Type (SFVT) Analysis of the HLA
Genetic Association in Juvenile Idiopathic Arthritis. Pac Symp Biocomput, 2010,
359-370.
Kennedy, L. J., Modrell, A.,
Single RM, Martin MP, and Carrington M. Statistical
and population genetic methods for KIR genes typed for presence/absence. Immunogenetics, 2008; 60(12): 711-725.
Martin MP, Single RM, Wilson MJ, Trowsdale J, and
Carrington M. KIR haplotypes
defined by segregation analysis in 59 Centre d’Etude Polymorphisme Humain
(CEPH) families. Immunogenetics,
2008; 60: 767-774.
Solberg
OD, Mack SJ, Lancaster AK, Single RM, Sanchez-Mazas A, Tsai Y, and Thomson G Balancing
selection and heterogeneity across the classical human leukocyte antigen loci:
A meta-analytic review of 497 population studies. Human Immunology, 2008; 69(7): 443-464.
Single RM, Meyer D, Mack SJ,
Mack SJ, Sanchez-Mazas A, Single RM, Meyer D, Hill J,
Dron HA, Jani AJ, Thomson G, Erlich HA. Biostatistics and Anthropology/Human
Genetic Diversity joint report: Population samples and genotyping technology. Tissue Antigens, 2007; 69: 188–191. (PDF)
Lancaster AK, Single RM, Nelson MP, Solberg O, Thomson
G. PyPop update - a software pipeline for large-scale multi-locus population
genomics. Tissue Antigens, 2007; 69:
192–197. (PDF)
Gourraud PA, Cambon-Thomsen A, Dauber EM, Feolo M,
Hansen J, Mickelson E, Single RM, Thomsen M, Mayr WR. Nomenclature for HLA
microsatellites. Tissue Antigens,
2007; 69: 210–213. (PDF)
Meyer* D, Single* RM, Mack SJ, Erlich H, and Thomson
G. Signatures of demographic history and natural selection in the human MHC
loci. Genetics 2006; 173: 2121-2142.
*joint first authors. (PDF)
Gao X, Single RM, Karacki P, Marti D, O’Brien SJ, and
Carrington M. Diversity of MICA and linkage disequilibrium with HLA-B in two
North American populations. Human
Immunology, 2006; 67: 152-158. (PDF)
Malkki* M, Single* R, Carrington M, Thomson G, and
Petersdorf E. MHC microsatellite diversity and linkage disequilibrium among
common HLA-A, HLA-B, DRB1 haplotypes: Implications for unrelated donor
hematopoietic transplantation and disease association studies. Tissue Antigens, 2005; 66: 114-124.
*joint first authors. (PDF)
Chen JJ, Duan T, Single RM, Mather KA, and Thomson G.
Hardy-Weinberg testing of a single homozygous genotype. Genetics 2005; 170: 1439-1442. (PDF)
Williams F, Meenagh A, Single R, McNally M, Kelly P,
Nelson MP, Meyer D, Lancaster A, Thomson G, and Middleton D. High resolution
HLA-DRB1 identification of a Caucasian population. Human Immunology, 2004 Jan; 65(1): 66-77. (PDF)
Cao K, Moormann AM, Lyke KE, Masaberg C, Sumba OP,
Doumbo OK, Koech D, Lancaster A, Nelson M, Meyer D, Single R, Hartzman RJ,
Plowe CV, Kazura J, Mann DL, Sztein MB, Thomson G, and Fernandez-Viña M.
Diversity of HLA class I-A, B and C alleles and haplotypes in five African
populations. Tissue Antigens, 2004;
63(4):293-325. (PDF)
Nicklas JA, Brooks EM, Hunter TC, Single R, and Branda
RF. Development of a quantitative PCR (TaqMan) assay for mitochondrial DNA copy
number and the common mitochondrial DNA deletion in the rat. Environmental and Molecular Mutagenesis,
2004; 44:313-320. (PDF)
Single RM, Meyer D, Hollenbeck J, Nelson M, Noble JA,
Erlich HA, and Thomson G. Haplotype
frequency estimation in patient populations: The effect of departures from
Hardy-Weinberg proportions and collapsing over a locus in the HLA region. Genetic Epidemiology, 2002; 22:186-195. (PDF)
Gordon D, Finch SJ, Jacobs
Single RM and Finch SJ. Gain in Efficiency from Using
Generalized Least Squares in the Haseman Elston Procedure. Genetic Epidemiology, 1995; 12:889-894. (PDF)
McCahill LE, Single RM, Aiello Bowles EJ, Feigelson
HS, James TA, Barney T, Engel JM, Onitilo AA. Variability in reexcision
following breast conservation surgery. JAMA. 2012 Feb 1;307(5):467-475.
Aiello Bowles E,Feigelson HS, Barney T, Broecker K,
Sterrett A, Bischoff K, Engel J, Gundersen G, Sheehey-Jones J, Single R, Onitilo A, James TA, and McCahill LE.
Improving quality of breast cancer surgery through development of a national
breast cancer surgical outcomes (BRCASO) research database. BMC Cancer 2012
12:136.
McCahill LE, Single R, Ratliff J, Sheehey-Jones J,
Gray A, James T. Local recurrence after partial mastectomy: relation to initial
surgical margins. Am J Surg. 2011 Mar;201(3):374-378
James T, McCahill LE, Ratliff J, Ashikaga T, Single R,
Sheehey-Jones J, Messier N, Stanley M, Krag D, Harlow S. Quality Assessment of
Neoadjuvant Therapy Use in Breast Conservation: Barriers to Implementation.The Breast Journal, Volume 15 Number 5,
2009; 524-526.
Privette A, McCahill L, Borrazzo E, Single RM, Zubarik
R. Laparoscopic approaches to resection of suspected gastric gastrointestinal
stromal tumors based on tumor location. Surgical
Endoscopy, 2008; 22(2): 487-494.
McCahill LE, Ahern JW, Gruppi LA, Limanek J, Dion GA,
Sussman JA, McCaffrey CB, Leary DB, Lesage MB, Single RM. Enhancing Compliance
With Medicare Guidelines for Surgical Infection Prevention: Experience With a
Cross-disciplinary Quality Improvement Team. Archives of Surgery, 2007
142: 355-361. (PDF)
Cook AD, Single R, and McCahill LE. Utilization of
surgical resection of primary tumors in patients presenting with Stage IV
colorectal cancer: An analysis of SEER data, 1988-2000. Annals of Surgical Oncology, 2005; 12(8): 637-645. (PDF)
Krag, DN, Julian, TB,
Krag D and Single RM. Breast cancer survival according
to number of nodes removed. Annals of
Surgical Oncology, 2003; 10: 1152-1159. (PDF)
Stokes IA, Henry SM, and
Kasprisin CA, Single PB, Single RM, Muller CB, and
Ferrier, JL. Improved mentor satisfaction: Emphasizing protégé training for
adult age mentoring dyads. Mentoring and Tutoring, 16(2), 163–174.
Single, PB and Single, RM. E-mentoring for social
equity: Review of research to inform program development. Mentoring and Tutoring, 2005; 13(2): 303-322. (PDF)
Single PB, Muller CB, Cunningham CM, Single RM, and
Carlsen WS. MentorNet: E-mentoring for
women students in engineering and science. Journal
of Women and Minorities in Science and Engineering, 2005; 11(3), 295-309. (PDF)
Kasprisin CA., Single PB, Single RM, and Muller CB.
Building a better bridge: Testing e-training to improve e-mentoring programs in
higher education. Mentoring and Tutoring,
2003; 11(1): 67-78. (PDF)
Single PB, Muller CB, Cunningham CM, and
Single, PB and Single, RM. Mentoring and the
technology revolution: A literature review on how face-to-face mentoring set
the stage for e-mentoring. In: F. K. Kochan & J. T. Pascarelli, eds.,
Creating successful telementoring programs.
Single
RM, Meyer D, and Thomson G. Statistical Methods for Analysis of Population
Genetic Data. In: J.A. Hansen, ed: Immunobiology of the Human MHC. Proceedings
of the 13th International Histocompatibility Workshop and Conference. Vol I,
IHWG Press, Seattle, 2007.
Single
RM, Meyer D, Mack SJ, Lancaster A, Nelson MP, Fernández-Viña M, Erlich H, and
Thomson G. Haplotype Frequencies and Linkage Disequilibrium among classical HLA
genes. In: J.A. Hansen, ed: Immunobiology of the Human MHC. Proceedings of the
13th International Histocompatibility Workshop and Conference. Vol I, IHWG
Press, Seattle, 2007.
Single
RM, Malkki M, Thomson G, Mather KA, Carrington M, and Petersdorf E. Linkage
Disequilibrium and HLA-A: B: DRB1 Haplotype Probabilities for Class I, II, III
Microsatellite Markers in Unrelated Donor Hematopoietic Stem Cell
Transplantation. In: J.A. Hansen, ed: Immunobiology of the Human MHC.
Proceedings of the 13th International Histocompatibility Workshop and
Conference. Vol I, IHWG Press, Seattle, 2007.
Meyer
D, Single RM, Mack SJ, Lancaster A, Nelson MP, Fernández-Viña M, Erlich H, and
Thomson G. Single locus polymorphism of
classical HLA genes. In: J.A. Hansen, ed: Immunobiology of the Human MHC.
Proceedings of the 13th International Histocompatibility Workshop and
Conference. Vol I, IHWG Press, Seattle, 2007.
Mack
SJ, Sanchez-Mazas A, Meyer D, Single R, Tsai Y, and Erlich HA. Methods used in
the generation and preparation of data for analysis in the 13th International
Histocompatibility Workshop. In: J.A. Hansen, ed: Immunobiology of the Human
MHC. Proceedings of the 13th International Histocompatibility Workshop and
Conference. Vol I, IHWG Press, Seattle, 2007.
Thomson
G, Hongzhe L, Dorman J, Lie BA, Mignot E, Steenkiste A, Thorsby E, Akey J,
McWeeney S, and Single RM. Statistical approaches for analyses of
HLA-associated and other complex diseases. In: J.A. Hansen, ed: Immunobiology
of the Human MHC. Proceedings of the 13th International Histocompatibility
Workshop and Conference. Vol I, IHWG Press, Seattle, 2007.
Mickelson
E, Damodaran A, He P, Malkki M, Smith A, Petersdorf E, Carrington M, Harding A,
Cambon-Thomsen A, Gagne K, Bignon J-D, Gebuhner L, Dubois V, Dormoy A, Tongio
M-M, Bois M, Concannon P, Martin B, Lie B, Thorsby E, Bétard C, Lathrop M,
Mignot E, Schroeder M, Reveille J, Feolo M, Inoko H, Thomson G, Single R, and
Hansen JA, on behalf of the IHWG Microsatellite Project and participating
laboratories. Standardization of Microsatellite Data: Comparative Analysis of
Results from 13th IHWS Participating Laboratories and Establishment of a
Microsatellite Reference Panel and Standard Nomenclature. In: J.A. Hansen, ed:
Immunobiology of the Human MHC. Proceedings of the 13th International
Histocompatibility Workshop and Conference. Vol I, IHWG Press, Seattle, 2007.
Reports and manuals
Glenys
Thomson, Hazael Maldonado-Torres, Alex K. Lancaster, Jill A. Hollenbach, Lisa
F. Barcellos, Steven J. Mack, Richard M.
Single. 2009. Testing fit of genotype frequencies to Hardy-Weinberg
proportions. Available online at: www.ImmPort.org
Steven
J. Mack, Richard M. Single, Henry A. Erlich, Glenys Thomson. HLA data
validation: A proposal for HLA data reporting for optimal utility
Bioinformatics Integration Support Contract (BISC), Phase II. 2008. Available
online at: www.ImmPort.org
Single
RM, Mather KA, Mack SJ, Maiers M, Gragert L. A Comparison of HLA and
Informative Microsatellite Markers for Population Group Assignment in Clustering.
National Marrow Donor Program (NMDP) technical report, 2008.
Single
RM, Maiers M, Gragert L. A comparison of the frequency of unique HLA-A, -B,
-DRB1 phenotypes in the donor registry and implications for registry modeling
and predictions. National Marrow Donor Program (NMDP) technical report, 2008.
Single
PB, Cunningham CM, Single RM, Nepton CN, and Kirk L. 2000-01 MentorNet
evaluation report, MentorNet Research Project. Evaluation Report, 2002; March;
Single RM and Finch SJ. Properties of the Null Distribution of the
GLS Test Statistic Applied to the Haseman-Elston Procedure. American Statistical Association Proceedings
of the Epidemiology Section 1997.
Finch
SJ, Yu Q, Lipfert FW, Baxter LA, Mendell NR, Thode HC Jr, Single RM and Gong
H. Review of External Costs of Air
Pollution with Respect to Human Health Effects.
Technical Report, 1995; AMS Report 95-11.
Mendell
NR, Lipfert FW, Finch SJ, Baxter LA, Grimson R, Larsen U, Single RM, Thode HC
Jr, and Yu Q. Ozone Pollution and Human Mortality: A Review of Studies
Applicable to Estimating the External Health Costs of Pollution. Technical Report, 1994; AMS Report No. 9413.