Chemistry 221

INSTRUMENTAL ANALYSIS
Intro/Noise/Noise Reduction Readings

Spring 2005


Readings in Skoog, Holler and Nieman

 
Chapter 1: pp. 1 - 18 
  • A general overview of the scope of instrumental analysis; fundamental terminology presented.
Appendix 1: pp. A1 - A20 (skim) 
  • This section is a good presentation of some fundamental statistics. If you are taking CHEM 201, this material will be covered (very rapidly!) in one of the lab lectures. Although you will not be tested on this material, I will expect you to know what standard deviations and confidence limits are. A good additional reference on this is Brewer's Problem Solving in Analytical Chemistry (on CHEM 121 reserve in the P/C Library). 
Chapter 3: pp. 53 - 68 (skim) 
  • This chapter is a nice summary of typical operational amplifier configurations. All you need to know is what op amps are and what they are used for (just so you're not surprised when you see one mentioned as part of a discussion of instrumentation later on). 
Chapter 4: pp. 73 - 76
pp. 76 - 96 (skim) 
  • You should gain an appreciation for the differences between analog and digital signals. Again, the goal here is to become familiar with the terminology so that you aren't confused when it turns up later (this material will be important when we start talking about noise and noise reduction). 
Chapter 5: pp. 99 - 113 
  • Your focus here should be on understanding the methods of signal-to-noise improvement and not on the electronic circuitry needed for these methods. 

OPTIONAL READINGS

  1. Analytical Chemistry, 44(6), 81A-88A (1972).
    Part 1 of Hieftje's classic S/N enhancement review

  2. Analytical Chemistry, 44(7), 69A-78A (1972).
    The thrilling conclusion of Hieftje's classic S/N enhancement two-part review

OPTIONAL LINKS

  1. "An Introduction to Signal Processing in Chemical Analysis"
    T.C. O'Haver's online presentation, including figures and links to the special software he used at the U. of Maryland to present this material.


Created and copyright by Joel M. Goldberg. Last updated: January 17, 2005

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