Round One:
The city of Townsville...is the site of the next major Hollywood picture, a remake of Charlie's Angels! This goes by unnoticed, until an anonymous caller tips the Powerpuff Girls off as to how evil the Hollywood denizens swarming about the fair city really are. And, in a mighty flash of Powerpuffery, the three little girls are rocketing through the sky going to check things out. Down below, the new Charlie's Angels are filming when they see the streaks of cartoon energy trailing behind the three cutest little girls ever. Realizing that the Powerpuff Girls are about to upstage them, the stars fire off their guns in an attempt to make sure no one ever sees anything better than their cheap plastic surgery. Unfortunately, the guns are stage weapons, and the Powerpuff Girls proceed to muck up the Angels' pretty features. Round One goes to the Powerpuff Girls.

Round Two:
Enter a shady monkey-like character with a habit of repeating himself, the man responsible for the anonymous call, "Mojo Jo...Overcoat." He meets up with Charlie's Angels after they are freshly recuperated from their wounds and brings them into a dark alley. Mojo explains to them that the Powerpuff Girls have been promoting violence over the television screen for years and must be stopped. To help them in their noble quest to defeat the Powerpuff Girls, Mojo dopes them up on some of his home made Chemical X, the source of the Powerpuff Girls' power. Charlie's Angels thereby gain superpowers, and combined with some good old fashioned marksmanship, nearly beat the Powerpuff Girls to death. Enter the narrator's woe over the defeat of the girls. Round Two goes to Charlie's Angels.

Round Three:
Realizing what they've done, the Angels stop just before completely destroying the Powerpuff Girls. At this point, the evil Mojo Jojo (if you don't know who this is, just accept that he is the bad guy) chooses to make his true identity known and prepares to fire a giant laser at the immobile Powerpuff Girls. Unfortunately, he restates his purpose over and over and over again for at least five minutes. Charlie's Angels prepare to leap into action, only to discover that their Chemical X was the cheap stuff they make down in Venezuela and has worn off by now. Then, realizing that they're action heroes in the first place, they shoot Mojo Jojo.