is studying Semphorin/Plexin/Collapsin Response Mediator Protein
signaling and its roles regulating vertebrate neuronal migration. She is also assisting
investigators with collaborative proteomics projects in UVM's Immunobiology COBRE.
Ryan is studying signaling mechanisms governing neuronal
migration during vertebrate brain development.
Zach Silberman --
UVM Integrated Biological Sciences Major. Zach is
molecular mechanisms of PACAP signaling in collaboration
with Victor May.
Jaye Grundy -- UVM Biochemistry Major. Jaye is studying PACAP Signaling.
Jonathan Karp -- UVM
Microbiology and Molecular Genetics Major.
Jonathan is studying signaling mechanisms in
a pathway critical to cell proliferation, growth, survival
Ras-MAPK signaling is hyperactive in more than 30%
of all tumors
and about twice this in pancreatic cancers and melanomas. These
studies are in collaboration with Philippe Roux.
Hayden Casali--UVM Integrated Biological Sciences Major.
Hayden is studying
Collapsin Response Mediator Proteins
their regulation by phosphorylation.
Rachael Bassett--UVM Integrated Biological Sciences Major.
Rachael is studying Semaphorin-Plexin signaling in vertebrate
central nervous system development.
Liam Kelley--UVM Biochemistry Major.
Liam is conducting studies
on the molecular
characterization of novel blood group antigens. These
studies are in collaboration with Lionel Arnaud.
Giovanna Stein--Norwich University Biochemistry Major.
Giovanna is studying Src Family Kinase Regulation and Function.
Hannah Johnson--UVM Biology Major.
Hannah is studying ESDN signaling.
Cody Crawford--UVM Biology Major. Cody is studying Ras-MAPK signaling.
Alex Lauzon--UVM Biological Science Major. Alex is studying Ras-MAPK-RSK signaling.
UVM Signaling Sister Labs
Several signaling projects are being conducted in collaboration with the labs of Professor Alicia Ebert and Professor Paula Deming
Norwich University Sister Laboratory
Professor Karen Hinkle Karen is studying novel regualtory
mechanisms of the Src family
of tyrosine kinases and their roles in neuronal migration using
biochemical, cellular and organsimal (c. elegans) approaches.
This work is in collaboration with Peter Juo.
Read about Karen's VGN Pilot Grant Award Here (page 4)!
Hinkle Lab Undergraduate StudentsCollaborative work at the interface of proteomics, genomics, ecology, evolution, phylogenetics, and environmental science:
Liz Chapdelaine and Zac Fulton
Several NSF-funded projects are being pursued and have been collaborative studies with:
--Jim Vigoreaux, to study the evolved roles of Flightin in insect muscle.
--Jim Carpenter, Fernando Gelin, Federico Lopez-Osorio, Ingi Agnarsson and the late Kurt Pickett to study the systematics and phylogenetics of the wasp subfamily Vespinae.
--Nick Gotelli, Aaron Elison and Amanda Northrop to study tipping points in the miniature ecosystem of the Northern Pitcher Plant.
--Nick Gotelli, Aaron Elison, Sara Helms Cahan, Nate Sanders, Rob Dunn, Andrew Nguyen, John Stanton-Geddes, Joel Parker, et al. to study evolved and acute molecular changes in ants in response to thermal stress and climate change.
Additional (Shorter Term) Alumni:
Marie Kenney--UVM Integrated Biological Sciences Major.
Anya Krymkowski--UVM Mathematics Major.
Caroline Casals--UVM Biology Major.
James Schreffler--UVM Biology Major.
Nick Thompson--UVM Biology Major.
Dave Harris--Neuroscience Rotation Student.
Nicole George--UVM Biology Major.