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Doctoral and Postdoctoral Training
Postdoctoral Fellow (2003-2006)
Department of Cell Biology,
Harvard Medical School
Dr. Steven P. Gygi,
advisor
Postdoctoral Fellow (2001-2003)
Division of Basic Sciences,
Fred Hutchinson Cancer
Research Center
Dr. Jonathan A. Cooper, advisor
Ph.D.(2001) Harvard University
Department of Cell Biology,
Harvard Medical School
Dr. John Blenis, advisor
Research
in the Ballif lab is primarily focused on elucidating molecular
mechanisms of signal transduction with two major emphases: (A)
genetically-defined signaling pathways regulating mammalian brain
development and (B) core signaling pathways regulating cell
proliferation, growth and survival. In addition to biochemical and
cell biological approaches,
we employ mass spectrometry-based proteomics as a primary tool to identify and quantitatively monitor proteins, their
modifications and their interactions with other proteins following
acute signal administration or across
developmental stages. A
second focus of our work involves developing and applying proteomic
methodology to advance diverse lines of biological inquiry, some of
which have had little to no interface with proteomics. This makes these
projects both exciting and challenging. These collaborative projects
range from the identification of novel human blood group antigens; to
the identification of host proteins that interact with arenavirus
proteins; to targeted proteomic characterizations of wasps, pitcher
plant ecosystems, ants, fruit flies, unicellular ciliates and parasitic protozoa.
Thanks to our Funding Sources
*NIH--The Vermont Genetics Network (the INBRE program of NIGMS), The COBRE program of NIGMS, DHHS
*NSF--Divisions: IOS and DEB *UVM--the Department of Biology, the College of Arts and Sciences and the Office of the VP of Research
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