Selected Publications from 1997-2001
1.Huang,
C., Ma, W-Y., Dawson, M.I., Rincón, M., Flavell, R.A., and
Dong, Z. (1997) “Blocking AP-1 activity, but not activating RARE, is required
for the anti-tumor promotion effect of retinoic acid”. Proc.
Natl. Acad. Sci. USA 94, 5826-5830.
2.Yang,
D., Kuan, C-y, Whitmarsh, A.J., Rincón, M., Zheng, T.S.,
Davis, R., Rakic, P., and Flavell, R.A. (1997) “Absence of excitotoxicity-induced
apoptosis in the hippocampus of mice lacking the Jnk3 gene”. Nature.
389, 865-870
3.Chow,
C-W., Rincón, M., Cavanagh, J., Dickens, M. and Davis, R.J.
(1997). “Nuclear accumulation of NFAT4 opposed by the JNK signal transduction
pathway”. Science.
278, 1638-1641.
4.Rincón,
M., Enslend,
H., Raingeaud, J., Recht, M., Penix, L.A, Michael, S-S. Su, Davis, R.J.
and Flavell, R.A. (1998)"Interferon-g expression by Th1 effector T cells
mediatd by the p38 MAP kinase signaling pathway". EMBO
J. 17, 2817-2829.
5.Anguita,
J., Rincón, M., Samanta, S., Barthold, S.W., Flavell, R.A.
and Fikrig, E. (1998) “Borrelia burgdorferi-infected, IL-6-deficient mice
have decreased Th2 responses and increased Lyme arthritis”.J.
Infect. Dis. 178, 1512-1515
6.Auphan,
N., Simon, A.K., Asnagli, H., Phillips, R.J., Rincón, M.
Ghosh, S., Flavell, R.A. Schmitt-Verhulst, A-M. (1998) “Consequences of
intrathymic TcR engagement by partial agonist on selection events and peripheral
T cell activation program”. J.
Immunol. 160, 4810-4821.
7.David,
J-P., Neff, L., Chen, Y., Rincón, M., Horne, W.C. and Baron,
R. (1998) “A new method to isolate rabbit osteoclast and osteoclast-like
cells: application to the characterization of the serum response element
binding proteins during osteoclast differentiation. J.
Bone. Mineral. Res.13, 1730-1738.
8.Yang
D., Conze D.B., Whitmarsh A.J., Barrett T., Davis R.J., Rincón
M. and Flavell, R.A. (1998) “Differentiation of CD4+ cells
to Th1 cells requires MAP kinase JNK2”. Immunity
9, 575-585.
9.Rincón,
M.,
Whitmarsh, A., Yang, D.D., Weiss, L., Dérijard, B., Jayaraj, P.,
Davis, R.J. and Flavell, R.A. (1998) “The JNK pathway regulates the in
vivo deletion of immature CD4+CD8+ thymocytes. J.
Exp. Med. 188, 1817-1830.
10.Chow,
C-W., Rincón, M. and Davis, R.J. (1999) “Transcription factor
NFAT is required for interleukin-2 production”. Mol.
Cell. Biol. 19, 2300-2307.
11.Fraser,
J.H., Rincón, M., McCoy, K.D., and Le Gros, G. (1999) “CTLA4
ligation attenuates AP-1, NFAT and NF-kB nuclear transcription factor activity
in activated T cells”. Eur.
J. Immunol.29, 838-844.
12.Merritt,
C., Enslen, H., Diehl, N., Conze, D., Davis, R.J. and Rincón,
M. (2000) “Activation of p38 MAP kinase in vivo selectively induces
apoptosis of CD8+, but not CD4+ T cells.”. Mol.
Cell. Biol. 20, 936-946.
13.Diehl,
N., Enslen, H., Fortner, K.A., Stetson, N., Charland, C., Flavell, R.A.,
Davis, R.J. and Rincón, M. (2000). “Activation of the p38
MAP kinase pathway arrests in vivo thymocyte differentiation and cell cycle
progression”. J.
Exp. Med. 191, 321-334
14.Weiss,
L., Wihtmarsh, A. Yang, D. Flavell, R.A., Davis, R.J. and Rincón,
M. (2000) “Regulation
of c-Jun NH2-terminal kinase(Jnk)gene
expression during T cell activation” J.
Exp. Med. 191, 139-145
15.Rincón,
M.,
Conze, D., Weiss, L., Diehl, N., Fortner, K.A., Yang, D., Flavell, R.A.,
Enslen, H., Whitmarsh, A.and Davis, R. (2000) “Do T cells care about the
MAP kinases signaling pathways?” Imm.
Cell. Biol. 78, 166-175.
16.Huang,
C., Ma, W., Rincón, M., Chen, N. and Dong, Z. (2000) “Involvment
of NFAT activation in UV response: evidence from cell culture and transgenic
mice”
J. Biol. Chem. 275, 9143-9149
17.Millet,
I., Phillips, R., Sherwin, R.S., Ghosh, S., Voll, R.E., Flavell, R.A.,
Vignery, A.and Rincón, M., (2000) “Inihibition of NF-kB activity
and enhancement of apoptosis by the neuropeptide calcitonin gene-related
peptide”. J.
Biol. Chem. 275, 15114-15121
18.
Zhang,
F., Rincón, M., Flavell, R.A. and Aune, T.M. (2000) “Defective
Th function induced by a dominant-negative cAMP response element binding
protein mutation is reversed by bcl-2” J.
Immunol. 165, 1762-1770.
20.Conze,
D., Lumsden, J., Enslen, H., Davis R.J., Le Gros, G. and Rincón,
M. (2000) “Activation of p38 MAP kinase in T cells facilitates the
immune response to the influenza virus”. Mol.
Immunol. 37, 503-513.
21.Diehl,
S., Anguita, J., Hoffmeyer, A., Zapton, T., Ihle, J.N., Fikrig, E., and
Rincón,
M.,(2000) “Inhibition of Th1 differentiation by IL-6 is mediated by
SOCS1”. Immunity.
13, 805-815.
22.Voll,
R.E., Jimi, E., Phillips, R.J., Barber, D.F., Rincón, M.,
Hayday, A.C., Flavell, R.A., and Ghosh, S. (2000) “NF-kB activation by
the pre-T cell receptor serves as a selective survival signal in T lymphocyte
development”. Immunity,
13, 677-689
23.Simon,
A.K., Auphan, N., Pophillat, M., Boyer, C., Ghosh, S.,
Rincón,
M., Flavell, R.A., Schmitt-Verhulst, A-M (2001) “The lack of NF-kB
transactivation and PKCe expression in CD4+CD8+ thymocytes correlates with
negative selection”.
Cell
Death Diff. 7, 1253-1262.
24.Guerder,
S., Rincón, M., Schmitt-Verhulst, A-M (2001) “Generation
of a transactivation-deficient RelA can control survival in CD8+ T cells
exposed to peripheral self-antigens”. J.
Immunol. 166, 4399-4407.
25.Rincón,
M.
(2001) “MAP kinase signaling pathways in T cells” Current
Opinion of Immunology, 166, 4399-4407.
26.David,
J.P., Rincón, M., Neff, L., Horne, W.C. and Baron, R (2001)
“Carbonic anhydrase II is an AP-1 target gene in osteoclasts”. J.
Cell. Physiol. 188, 89-97.
27.Rincón,
M.,
Flavell, R.A. and Davis, R.J. (2001) Signal transduction by MAP kinases
in T lymphocytes” Oncogene
20, 2490-2497.
28.Timblin,
C., Robledo, R., Rincón, M., Cummins, A., Pfeiffer, L., and
Mossman, B. T. (2001) “Transgenic mouse models to determine the role of
epidermal growth factor receptor in epithelial cell proliferation, apoptosis
and asbestosis” Chest,
120, 22S-24S.
29.Hubbard,
A. K.., Timblin, C.R., Rincón, M., Mossman, B.T. (2001) “Use
of transgenic luciferase reporter mice to determine activation of transcription
factors and gene expression by fibrogenic particles”. Chest,
120, 24S-25S
30.Conze,
D., Weiss, L., Bhushan, A., Johnson, P., and Rincón, M.,
(2001). “Autocrine prodction of interleukin 6 causes multidrug resistance
in breast cancer cells”. Cancer
Research. 61, 8851-8858