Selected Publications from 1997-2001
 
1.Huang, C., Ma, W-Y., Dawson, M.I., Rincón, M., Flavell, R.A., and Dong, Z. (1997) “Blocking AP-1 activity, but not activating RARE, is required for the anti-tumor promotion effect of retinoic acid”. Proc. Natl. Acad. Sci. USA 94, 5826-5830.
2.Yang, D., Kuan, C-y, Whitmarsh, A.J., Rincón, M., Zheng, T.S., Davis, R., Rakic, P., and Flavell, R.A. (1997) “Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene”. Nature. 389, 865-870
3.Chow, C-W., Rincón, M., Cavanagh, J., Dickens, M. and Davis, R.J. (1997). “Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway”. Science. 278, 1638-1641.
4.Rincón, M., Enslend, H., Raingeaud, J., Recht, M., Penix, L.A, Michael, S-S. Su, Davis, R.J. and Flavell, R.A. (1998)"Interferon-g expression by Th1 effector T cells mediatd by the p38 MAP kinase signaling pathway". EMBO J. 17, 2817-2829.
5.Anguita, J., Rincón, M., Samanta, S., Barthold, S.W., Flavell, R.A. and Fikrig, E. (1998) “Borrelia burgdorferi-infected, IL-6-deficient mice have decreased Th2 responses and increased Lyme arthritis”.J. Infect. Dis. 178, 1512-1515
6.Auphan, N., Simon, A.K., Asnagli, H., Phillips, R.J., Rincón, M. Ghosh, S., Flavell, R.A. Schmitt-Verhulst, A-M. (1998) “Consequences of intrathymic TcR engagement by partial agonist on selection events and peripheral T cell activation program”. J. Immunol. 160, 4810-4821
7.David, J-P., Neff, L., Chen, Y., Rincón, M., Horne, W.C. and Baron, R. (1998) “A new method to isolate rabbit osteoclast and osteoclast-like cells: application to the characterization of the serum response element binding proteins during osteoclast differentiation. J. Bone. Mineral. Res.13, 1730-1738.
8.Yang D., Conze D.B., Whitmarsh A.J., Barrett T., Davis R.J., Rincón M. and Flavell, R.A. (1998) “Differentiation of CD4+ cells to Th1 cells requires MAP kinase JNK2”. Immunity 9, 575-585.
9.Rincón, M., Whitmarsh, A., Yang, D.D., Weiss, L., Dérijard, B., Jayaraj, P., Davis, R.J. and Flavell, R.A. (1998) “The JNK pathway regulates the in vivo deletion of immature CD4+CD8+ thymocytes. J. Exp. Med. 188, 1817-1830.
10.Chow, C-W., Rincón, M. and Davis, R.J. (1999) “Transcription factor NFAT is required for interleukin-2 production”. Mol. Cell. Biol. 19, 2300-2307.
11.Fraser, J.H., Rincón, M., McCoy, K.D., and Le Gros, G. (1999) “CTLA4 ligation attenuates AP-1, NFAT and NF-kB nuclear transcription factor activity in activated T cells”. Eur. J. Immunol.29, 838-844.
12.Merritt, C., Enslen, H., Diehl, N., Conze, D., Davis, R.J. and Rincón, M. (2000) “Activation of p38 MAP kinase in vivo selectively induces apoptosis of CD8+, but not CD4+ T cells.”. Mol. Cell. Biol. 20, 936-946.
13.Diehl, N., Enslen, H., Fortner, K.A., Stetson, N., Charland, C., Flavell, R.A., Davis, R.J. and Rincón, M. (2000). “Activation of the p38 MAP kinase pathway arrests in vivo thymocyte differentiation and cell cycle progression”. J. Exp. Med. 191, 321-334
14.Weiss, L., Wihtmarsh, A. Yang, D. Flavell, R.A., Davis, R.J. and Rincón, M. (2000) “Regulation of c-Jun NH2-terminal kinase(Jnk)gene expression during T cell activationJ. Exp. Med. 191, 139-145
15.Rincón, M., Conze, D., Weiss, L., Diehl, N., Fortner, K.A., Yang, D., Flavell, R.A., Enslen, H., Whitmarsh, A.and Davis, R. (2000) “Do T cells care about the MAP kinases signaling pathways?” Imm. Cell. Biol. 78, 166-175.
16.Huang, C., Ma, W., Rincón, M., Chen, N. and Dong, Z. (2000) “Involvment of NFAT activation in UV response: evidence from cell culture and transgenic mice” J. Biol. Chem. 275, 9143-9149
17.Millet, I., Phillips, R., Sherwin, R.S., Ghosh, S., Voll, R.E., Flavell, R.A., Vignery, A.and Rincón, M., (2000) “Inihibition of NF-kB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide”. J. Biol. Chem. 275, 15114-15121
18.Zhang, F., Rincón, M., Flavell, R.A. and Aune, T.M. (2000) “Defective Th function induced by a dominant-negative cAMP response element binding protein mutation is reversed by bcl-2” J. Immunol. 165, 1762-1770.
19.Rincón, M., Flavell, R.A. and Davis, R.A. (2000) “The JNK and p38 MAP kinase signaling pathways in T cell-mediated immune responses”. Free Radic. Biol. Med. 28, 1328-1337
20.Conze, D., Lumsden, J., Enslen, H., Davis R.J., Le Gros, G. and Rincón, M. (2000) “Activation of p38 MAP kinase in T cells facilitates the immune response to the influenza virus”. Mol. Immunol. 37, 503-513.
21.Diehl, S., Anguita, J., Hoffmeyer, A., Zapton, T., Ihle, J.N., Fikrig, E., and Rincón, M.,(2000) “Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1”. Immunity. 13, 805-815.
22.Voll, R.E., Jimi, E., Phillips, R.J., Barber, D.F., Rincón, M., Hayday, A.C., Flavell, R.A., and Ghosh, S. (2000) “NF-kB activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development”. Immunity, 13, 677-689
23.Simon, A.K., Auphan, N., Pophillat, M., Boyer, C., Ghosh, S., Rincón, M., Flavell, R.A., Schmitt-Verhulst, A-M (2001) “The lack of NF-kB transactivation and PKCe expression in CD4+CD8+ thymocytes correlates with negative selection”. Cell Death Diff. 7, 1253-1262.
24.Guerder, S., Rincón, M., Schmitt-Verhulst, A-M (2001) “Generation of a transactivation-deficient RelA can control survival in CD8+ T cells exposed to peripheral self-antigens”. J. Immunol. 166, 4399-4407

25.Rincón, M. (2001) “MAP kinase signaling pathways in T cells” Current Opinion of Immunology, 166, 4399-4407.

26.David, J.P., Rincón, M., Neff, L., Horne, W.C. and Baron, R (2001) “Carbonic anhydrase II is an AP-1 target gene in osteoclasts”. J. Cell. Physiol. 188, 89-97.

27.Rincón, M., Flavell, R.A. and Davis, R.J. (2001) Signal transduction by MAP kinases in T lymphocytes” Oncogene 20, 2490-2497.

28.Timblin, C., Robledo, R., Rincón, M., Cummins, A., Pfeiffer, L., and Mossman, B. T. (2001) “Transgenic mouse models to determine the role of epidermal growth factor receptor in epithelial cell proliferation, apoptosis and asbestosis” Chest, 120, 22S-24S.

29.Hubbard, A. K.., Timblin, C.R., Rincón, M., Mossman, B.T. (2001) “Use of transgenic luciferase reporter mice to determine activation of transcription factors and gene expression by fibrogenic particles”. Chest, 120, 24S-25S

30.Conze, D., Weiss, L., Bhushan, A., Johnson, P., and Rincón, M., (2001). “Autocrine prodction of interleukin 6 causes multidrug resistance in breast cancer cells”. Cancer Research. 61, 8851-8858