Ian A.F. Stokes, Ph.D. www.uvm.edu | 
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    Ian A.F. Stokes, Ph.D.
     Research Professor  Emeritus 
      Orthopaedics and Rehabilitation  
      434 Stafford Hall,  
      Burlington, Vermont 05405-0084, USA  
      Phone : (802) 656-2250  
      Fax: (802) 656-4247   | 
	    
    
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  Description of Research Program 
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  Address / Contact 
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  Recent Publications - go to CV 
     
     
    Curriculum Vitae
    Ian Stokes' CV  
    Academic Links
    Department of Orthopaedics
        and Rehabilitation, University of Vermont 
    International Research Society of
        Spinal Deformities 
    Scoliosis Research Society 
	 Scoliosis Research Society Glossaries 
     
    Other Links
    Vermonters for Justice in Palestine 
    Richmond Trails Committee 
    Old Spoke Home Community Workshop (Formerly Bike Recycle Vermont) 
    Local Motion 
    TrailFinder 
    Hendrix Quote 
    
     
     
    Machines for Burning Fossil Fuels
    1948 Douglas Motorcycle Mk III (Owned 1966-2017)
     
    
        Citroën 'Traction avant' 7C (1936)
  
 
     Description of Research Program
    Dr Stokes' primary research interest was in problems of the spine,
    including muscle function around the lumbar spine and spinal
    deformity and growth plate biomechanics, with an emphasis on using
    biomechanical modeling and simulation.  
     
     A. Mechanical modulation of growth and progression of spinal
      deformity.
        Experimental (animal) models were used to determine sensitivity of
    growth plates in long bones and vertebrae to mechanical load.
    Quantitative histology (fluorescent labelling, cellular morphology,
    BrDU labeling, etc.) were used to investigate cellular responses
    mechanical forces in growth plates of different species and
    anatomical locations, having different base-line growth velocities.
     
    
    This is combined with analytical determinations of the loading
      asymmetry of vertebrae in spines with scoliosis in order to make a
      predictive model of the progression of deformity. Results were
      compared with clinical (radiographic) studies of patients during
      the adolescent growth period.  
       
      B. Stability of muscular loading of the lumbar spine.
    This work examined the idea that the spine might be 'self-injured' during
    buckling events resulting from unstable equilibrium under the action
    of muscular forces. Results confirmed that muscular stiffness
    (which depends on muscle activation) is required normally for
    stability. Analytical modeling determined conditions under
    which the spine is at risk for such 'self-injury', and experimental
    (EMG) measurements of human subjects were used to compare model
    predictions with the theoretical predictions. This work also
    involved experimental studies of the spinal motion segment stiffness
    with axial preload.  
     
       
    
    
        
      ADDRESS
      University of Vermont 
      Dept. of Orthopaedics and Rehabilitation 
      434 Stafford Hall 
      Burlington, VT 05455-0084, USA 
       
       Author: Ian Stokes, Ian.Stokes@uvm.edu
       Last revised/updated: January 2019 
      
      URL: https://www.uvm.edu/~istokes/index.html  
      Comments: Ian.Stokes@uvm.edu
      
  
    
 
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