Associate Professor

Dr. Rachael Oldinski's research program revolves around sustainable biomaterial design and fabrication for drug delivery, tissue engineering, and regenerative medicine applications. The Engineered Biomaterials Research Laboratory, under Dr. Oldinski's direction, investigates the fundamental understanding and development of polymeric materials for biological applications with a specific emphasis on tissue regeneration and drug delivery. Specifically, Dr. Oldinski's group critically and logically examines the role biomaterials and physical environments play to impact cell behavior. Areas of interest include: (i) developing novel polymeric materials and precursors; (ii) utilizing processing techniques to fabricate scaffolds with the desired micro- and
macroscopic structures both spatially and temporally; (iii) investigating the interaction of cells with these materials while developing materials-based techniques to control cell differentiation; and (iv) using polymers to control the delivery of therapeutic molecules, including anticancer agents.

Related Links:

Oldinski Laboratory

Publications

  1. 1. Esmat Jalalvandi, Patrick Charron, Rachael A. Oldinski. Physico-mechanical characterization of liquid versus solid applications of visible light crosslinked tissue sealants. ACS Applied Bio Materials, 2019. In print.
  2. Patrick N. Charron, Tess Braddish, Rachael A. Oldinski. PVA-gelatin hydrogels formed using combined theta-gel and cryo-gel fabrication techniques. Journal of the Mechanical Behavior of Biomedical Materials, v.92: 90-96, 2019. https://doi.org/10.1016/j.jmbbm.2019.01.002
  3. Jennifer Etter, Rachael A. Oldinski. Synthesis of a Tri-network Alginate Hydrogel for use as an Injectable Cell Carrier. Biomedical Physics & Engineering Express, v.5(1): 015017, 2018. https://doi.org/10.1088/2057-1976/aaeb6f
  4. Jennifer Etter, Michael Karasinski, Jesse Ware, Rachael A. Oldinski. Dual-crosslinked homogeneous alginate microspheres for mesenchymal stem cell encapsulation. Journal of Materials Science: Materials in Medicine, v.29(9):143, 2018. https://doi.org/10.1007/s10856-018-6151-4
  5. Spencer L. Fenn, Patrick N. Charron, Rachael A. Oldinski. Anti-cancer therapeutic alginate-based tissue sealants for lung repair. ACS Applied Materials and Interfaces, v.9(28): 23409-23419, 2017. http://pubs.acs.org/doi/abs/10.1021/acsami.7b04932
  6. Patrick N. Charron, Sarah Blatt, Canaan McKenzie, Rachael A. Oldinski. Dynamic mechanical response of PVA-gelatin theta-gels for nucleus pulposus tissue replacement. Biointerphases*, v.2(12), 02C409, 2017. http://dx.doi.org/10.1116/1.4982643
  7. Spencer L. Fenn, Tianxin Miao, Ryan Scherrer, Rachael A. Oldinski. Dual-crosslinked alginate sub-microspheres for intracellular chemotherapeutic delivery. ACS Applied Materials and Interfaces, v.8(8): 17775-83, 2016. http://dx.doi.org/10.1021/acsami.6b03245

Areas of Expertise and/or Research

Biomaterials Engineering, Sustainable Materials, Medical Device Design, Tissue Engineering

Education

  • M.S. and Ph.D. Mechanical Engineering (Colorado State University)
  • B.S. Biomedical Engineering (Michigan Technological University)

Contact

Phone:
  • 802-656-3338
Office Location:

201D Votey Hall

Office Hours:

By appointment

Website(s):
  1. Rachel's Website

Courses Taught

  • ME101 Materials Science and Engineering 2011 – Present
  • ME201 Biomaterials Engineering 2012 – Present
  • ME014 Mechanics of Solids 2014 – Present
  • ME207 Bioengineering 2015 – 2017