Warren I. Schaeffer

CURRICULUM VITAE FOR

HOME ADDRESS

24 Southwind Drive, Burlington, Vermont 05401 Phone/Fax: (802)863-3593
As of April 15, 2004: 17 Tived Lane, Edison, New Jersey 08837
email: wschaeff@uvm.edu or wicatera@aol.com

OFFICE ADDRESS

University of Vermont Microbiol. & Molec. Genet. Dep't. B-009 Stafford Building Burlington, Vermont 05405 Phone: (802)656-2290, Fax: (802)656-8749
e-mail: wschaeff@uvm.edu

EDUCATION

Ph.D. (Bacteriology) - 1964 - Rutgers University, New Brunswick, N. J.
M. S. (Bacteriology) - 1962 - Rutgers University, New Brunswick, N. J.
B. S. (Animal Sciences) - 1960 - Rutgers University, New Brunswick, N. J.

EMPLOYMENT HISTORY

Associate Dean of the Graduate College, University of Vermont, Burlington, Vermont, 1994-1997.
Professor, Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, l976-2003, Retired, June, 2003
Chair, Department of Microbiology (now Microbiology and Molecular Genetics), University of Vermont, Burlington, Vermont, l979-1988.
Acting Chair, Department of Medical Microbiology, University of Vermont, Burlington, Vermont, l978-79.
Associate Professor, Department of Medical Microbiology, University of Vermont, Burlington, Vermont, l97l-76.
Assistant Professor, Department of Medical Microbiology, University of Vermont, Burlington, Vermont, l967-7l.
Assistant Professor, Department of Medical Microbiology, University of California - Irvine, Irvine, California, l966-67.
Research Associate, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, l964-66.
Research Assistant, Department of Bacteriology, Rutgers University, New Brunswick, New Jersey, l960-64.

HONORS

Received the Society for In Vitro Biology Distinguished Service Award, 1994
AARP Distinguished Service Award, December, 2003

MEMBERSHIP IN PROFESSIONAL SOCIETIES

American Society for Microbiology
Society for In Vitro Biology
Society of the Sigma Xi American
Association for the Advancement of Science

COMMITTEE AND SERVICE ACTIVITIES

CURRENT (University, National and International)

UNIVERSITY

Chair, Departmental Curriculum Committee - 1992-2003
Director Departmental Undergraduate Program - 1992-2003.
Chair Departmental Student Affairs Committee - 1991-2003
Grand Marshall, College of Agriculture & Life Sciences Graduation - 1993-2003.
Elected President of the Board, Hillel at University of Vermont - 1999-2001
Member of the Board, Hillel at University of Vermont - 1999-2003

NATIONAL AND INTERNATIONAL

Member of the Executive Council of the Vermont Chapter of AARP, (2001 - Present); Acting State President, (2002).
Editor-in-Chief, Methods in Cell Science, Kluwer Academic Publishers, The Netherlands.
Member of Editorial Board for In Vitro Cellular and Developmental Biology and ad hoc reviewer of journals.
Ad hoc reviewer of Grants for National Science Foundation, National Institutes of Health and the Department of Veterans Affairs Medical Center.
Chair of the Society for In Vitro Biology Terminology Committee. 1978-1982; 1988-2003.
Appointed by President of the Tissue Culture Association as the Association's representative to the International Association for Cell Culture. 1988-2003
Appointed Chair, Terminology Committee, International Association for Cell Culture. 1989-2003
Chair, Membership Committee, Tissue Culture Association. 1990 -1996
Appointed Chair, Tissue Culture Association Task Force to restructure and rename the Association.
Member of the Council of the Tissue Culture Association. (1988 ).

PAST (University)

Member of the College of Medicine Committee on Medical Student Advancement 1979-1995.
Member of the Senate Student Affairs Committee (1989-1996)
Member of the Presidential Panel on Alcohol -1995
Member of the Faculty Participation in Governance Committee. (1969-1970)
Member of the College of Medicine Curriculum Advisory Committee. (1969-1970)
Member of the University Institutional Grants Committee (Now University Committee on Research and Scholarship). (1970-1974)
Member of the Ad Hoc Health Science Committee on Teaching in the Allied Health Sciences. (1972-1973)
Chaired the College of Medicine Research Committee for five years and a member for seven years. (1975-82)
Chaired the College of Medicine Graduate Education Committee for four years from its inception. (1976-1980)
Member of the Committee to Review University Teaching of Chemistry. (1980-1981)
Chaired the Search Committee for the Chair of Medical Biochemistry (1980-1981)
Member of the President Coor's Presidential Inaugural Committee on Graduate Education and Research. (1980)
Chaired Academic Senate Committee charged with creating the Senate Committee on Research and Scholarship. (1983)
Chaired the Search Committee for the first Director of the School of Business Administration. (1983)
Chaired the Review Committee for the Associate Vice President for Research and Dean of the Graduate School. (1984)
Member of the College of Medicine Faculty Standards Committee. (1983-1986)
Member of the College of Medicine, Dean's Executive/Advisory Committee. (1979-1988)
Chair of the Department of Animal Sciences Chair Search Committee. (1988).
Member of the Graduate College Executive Committee. 1973-1976 and 1989-1992.
Appointed by Dean of Graduate College to serve on the grants subcommittee of the University Committee on Research and Scholarship, September, 1990.
Elected by College to serve on the Dean of the College of Medicine Search Committee, November, 1990.
Appointed Chair of the Greek Review Presidential Task Force, 1991 to 1992.
Member Senate Financial Policy Committee -1994-2002.
Member of the College of Agriculture and Life Sciences Faculty Standards Committee. 1988-2002; Chair, 1994-2002.

PAST (National & International)

National Secretary of the Tissue Culture Association. Elected in 1984. Reelected in 1986. Served to 1988.
Member of the Executive Board of the Tissue Culture Association - 1984-1988.
Taught Tissue Culture Association's "Primary Cell Culture Course" at W. Alton Jones-Cell Science Center, Lake Placid, N. Y. for five years.
Member of evaluation team for New England Association of Schools and Colleges to the Massachusetts College of Optometry - 1980 and 1985.

Presented seminars at: University of California-San Diego,
University of Arizona,
University of Colorado-Denver Medical School,
University of New Hampshire,
New York Academy of Sciences,
National Institutes of Health,
Zhejiang Institute of Experimental Medicine and Hygiene, Hangzhou, Zhejiang, China.
Member of Site Visit Team for National Institutes of Health to University of Virginia, Medical School, Liver Biology Program Project Proposal. Member of Site Visit Team for National Institutes of Health, National Cancer Institute to University of North Carolina, Medical School, Chemical Carcinogenesis Program Project. (1986)
Consultant for Miles Research Institute, Miles Laboratories, Elkhart, Indiana.
Member of Site Visit Team for New England Association of Schools and Colleges for evaluation of Massachusetts General Hospital Institute of Health Professions. April 29-May 2, 1990.

SUPERVISION OF THESIS/DISSERTATION RESEARCH

John C. Bausher: "Studies of the Effects of Aflatoxin B1 on Rat Liver Cells in vitro"; Ph.D., October, 1973. Current Position: Physician
Naomi Rosenberg: "Isolation and Characterization of Revertants from Human SV40-Transformed Cells"; Ph.D., Oct., 1973. Current Position: Prof., Tufts U.
Michael D. Polifka: "Development of Morphological Variants with time in a spontaneously transformed cloned epithelial rat liver cell culture"; M.S., October, 1974. Current Position: Physician
Barbara Israel: "Analysis of Cytoplasmic Modulation of the Transformed Phenotype in a Homologous Rat Hepatocyte Cell Culture System"; Ph.D., March, 1981. Current Position: Research Scientist, Univ. Wisc.; CEO Platypus Enterprises
Nicholas Heintz: "Cytosolic Binding of 3-Methylcholanthrene in Cultured Rat Hepatocytes"; Ph.D., October 1979. Current Position: Prof., Pathology Department, U. Vermont

MEMBERSHIP ON THESIS/DISSERTATION COMMITTEES

Student's Name Department Degree Year
James Trzaskas Biochemistry Ph.D. March, 1979
Stephen Jenkins Microbiology Ph.D. October, 1979
Nicholas Heintz Microbiology Ph.D. October, 1979
Barbara Israel Microbiology Ph.D. March, 1981
Robert Sheyka Microbiology M.S. May, 1980
Paul Liberator Biochemistry Ph.D. May, 1981
Pamela Little Microbiology Ph.D. March, 1982
Carol Mullin Microbiology M.S. May, 1982
John Didsbury Microbiology Ph.D. March, 1983
Louise Nutter Biochemistry Ph.D. May, 1983
Linda Shonk Cell Biology M.S. May, 1983
Joseph Santangelo Agric. Micro. M.S. May, 1984
Laurie Elder Microbiology Ph.D. May, 1984
Anne Burkhardt Biochemistry Ph.D. May, 1984
Ingrid Ratsep Agric. Micro. Ph.D. May, 1984
Debby Boles Zoology M.S. May, 1984
Jason Kittler Biochemistry Ph.D. May, 1985
Randolph Bretton Cell Biology Ph.D. May, 1986
Eunice Froeliger Microbiology Ph.D. May, 1988
Alastair M. Mackay Cell Biology Ph.D. February, 1989
M. Kadima-Nzuji Microbiology Ph.D October, 1989
Eric Holden Micro.& Mol.Gen. M.S. September, 1990
Todd Pritchard Animal Science M.S. May, 1991
Michael Ziman Cell & Molec.Biol. Ph.D. January, 1994
Theresa Casey Anim.& Food Sci. M.S. 1997
Todd Pritchard Animal Science M.S. May, 1999
Wenhong Fan Anim.& Food Sci. Ph.D., 2000

PUBLICATIONS

1. Schaeffer, W. I., P. E. Holbert, and W. W. Umbreit. l963. Attachment of Thiobacillus thiooxidans
to sulfur crystals. J. Bact., 85: l37.

2. Schaeffer, W. I., and W. W. Umbreit. l963. Phosphotidyl inositol as a wetting agent in sulfur oxidation by Thiobacillus thiooxidans . J. Bact., 85: 492.

3. Schaeffer, W. I. l964. Fixation of carbon dioxide into phosphotidyl inositol formed by Thiobacillus thiooxidans as a sulfur wetting agent. Bact. Proc., p.9l.

4. Gabliks, J., W. Schaeffer, L. Friedman, and C. Wogan. l965. Effect of aflatoxin Bl on cell cultures.
J. Bact., 90: 720.

5. Schaeffer, W. I., J. Gabliks, and R. Calitis. l966. Interaction of staphylococcal enterotoxin B with
cell cultures of human embryonic intestine. J. Bact., 9l: 2l.

6. Gabliks, J., G. Strachan, and W. I. Schaeffer. l966. Effect of specific amino acid deficiencies on viral replication in cell cultures. Proc. 7th International Congress of Nutrition.

7. Schaeffer, W. I., and J. Gabliks. l967. Interference by trypsin of the cytotoxicity of staphylococcal enterotoxin B upon human intestine cell cultures. Meeting Abstract: Bact. Proc. p.82.

8. Schaeffer, W. I., J. Gabliks, and R. Calitis. l967. Interference by trypsin in the interaction of staphylococcal enterotoxin B and cell cultures of human embryonic intestine. J. Bact., 93:l489.

9. Stinebring, W. R., and W. I. Schaeffer. l968. Modification of interferon effect by treatment of cells with "trypsin". Meeting Abstract: Bact. Proc., p.l48.

l0. Schaeffer, W. I. l969. Cell culture cytotoxicity to staphylococcal enterotoxin B: The effect of the type of
growth serum and testing procedures. Bact. Proc., p.80.

11. Schaeffer, W. I. l970. Interaction of staphylococcal enterotoxin B with cell cultures: I. Effect of serum
and testing procedures. Infection and Immunity, l: 455.

l2. Savel, H., B. Forsyth, W. Schaeffer, and T. Cardella. l970. Effect of aflatoxin Bl on cultured human peripheral blood lymphocytes. Proc. Soc. Exptl. Biol. Med., l34: lll2.

l3. Bland, J. H., G. O'Connor, and W. I. Schaeffer. l97l. Fibrodysplasia ossificans progressiva: A study of collagen and glycosaminoglycans. Arthritis and Rheumatism, l4: l5l.

l4. Bausher, J. C., and W. I. Schaeffer. l974. A diploid rat liver cell culture. I. The isolation and sensitivity to aflatoxin Bl. In Vitro, 9: 286.

l5. Bausher, J. C., and W. I. Schaeffer. l974. A diploid rat liver cell culture. II. Effect of aflatoxin Bl on RNA
synthesis in vitro. In Vitro, 9: 294.

l6. Schaeffer, W. I., N. E. Smith, P. A. Payne, and D. M. Wilson. l974. The physiological and biochemical effect of the mycotoxin patulin on Chang liver cell cultures. In Vitro, ll: 69-77.

l7. Schaeffer, W. I., and M. D. Polifka. l975. A diploid rat liver cell culture. III. Characterization of the heteroploid morphological variants which develop with time in culture. Exp. Cell Res.,95: l67-l75.

l8. Rosenberg, N., W. I. Schaeffer, and Leila Diamond. l975. Isolation of variant cells from SV-40 transformed human diploid fibroblasts. Can. Res., 35: l970-l974.

l9. Schaeffer, W. I., and K. Friend. l976. Efficient detection of soft agar grown colonies using a tetrazoleum salt. Cancer Letters, l: 259.

20. Schaeffer, W. I., N. H. Heintz, A. H. L. Chuang, and E. Bresnick. l977. Sensitivity of early vs late passages of a rat hepatocyte culture for toxicological studies of carcinogens. In Vitro, l3: l54.

2l. Schaeffer, W. I., and N. H. Heintz. l978. A diploid rat liver cell culture. IV. Malignant transformation by
aflatoxin Bl. In Vitro, l4: 4l8- 427.

22. McMahon, J. B., W. I. Schaeffer, P. C. Kelleher, and C. J. Smith. l978. Synthesis of alpha-fetoprotein molecular variants by hepatoma cells in vitro and in vivo. Meeting Abstract.

23. Schaeffer, W. I., A. H. L. Chuang, N. H. Heintz, and E. Bresnick. l979. Sensitivity of a cloned diploid rat liver cell line to aflatoxin Bl and benzo(a)pyrene. In Vitro, l5: 437-440.

24. Schaeffer, W. I. l979. Proposed usage of animal tissue culture terms: Usage of vertebrate cell, tissue and organ culture terminology. In Vitro, l5: 649-653.

25. Heintz, N., B. Little, E. Bresnick, and W. I. Schaeffer. l980. Malignant trans-formation of cultured rat hepatocytes by (+) and (-)-trans,8-dihydro- 7,8-dihydroxy-benzo(a)pyrene. Can. Res., 40: l28l-1285.

26. Schaeffer, W. I. l980. The long-term culture of a diploid rat hepatocyte cell strain. In: C. Borek and G. M. Williams (ed.), Differentiation and carcinogenesis in liver cell cultures. Annals N. Y. Acad. of Sciences, 349: l65-l82.

27. Schaeffer, W. I., and D. Kessler. l980. Human liver cells in culture. In: Methods in Cell Biology, 2l: Part B: 457-473. Academic Press, N. Y.

28. Tierney, B., D. Weaver, N. Heintz, W. I. Schaeffer, and E. Bresnick. l980. The identity and nuclear uptake of a cytosolic binding protein for 3- methylcholanthrene. Arch. Biochem., 200:5l3-523.

29. Heintz, N., B. Tierney, E. Bresnick, and W. I. Schaeffer. l98l. Saturable high affinity binding of 3-methylcholanthrene to a 4S cytoplasmic protein; correlation to induction of aryl hydrocarbon hydroxylase in cultured rat hepatocytes. Can. Res., 4l: l794-l802.

30. Israel, B. A., and W. I. Schaeffer. 1982. Cytoplasmic hybrids (cybrids) and reconstructed cells between
normal and tumorigenic rat liver cells: Suppression of the tumorigenic phenotype. (Abstract) In Vitro, 18: 284.

31. Schaeffer, W. I., B. F. vonKreuter, E. A. Reichard and G. Sato. 1983. The selection of malignantly transformed rat liver cells using a hormonally defined medium. In Vitro, 19: 108-110.

32. Schaeffer, W. I. 1984. Usage of Vertebrate, Invertebrate and Plant Cell, Tissue and Organ Culture Terminology. In Vitro, 20:19-24.

33. Schaeffer, W. I. 1985. Nomenclature of cells in culture. In Vitro, In Monograph #5, Uses and Standardization of Vertebrate Cell Cultures. Tissue Culture Association, Gaithersburg, Maryland, pgs. 19-24.

34. Schaeffer, W. I. and B. A. Israel. 1987. Cytoplasmic Suppression of Malignancy; In Vitro Cellular and
Developmental Biology 23(9):627-632.

35. Houser, W. H., C. K. Cunninghanm, R. N. Hines, W. I. Schaeffer and E. Bresnick. 1987 Interaction of the 4S Polycyclic Aromatic Hydrocarbon Binding Protein with the Cytochrome P450c Gene; Archives of Biochemistry and Biophysics, 259(1):215-223.

36. Israel, B. A. and W. I. Schaeffer. 1988. Cytoplasmic Mediation of Malignancy; In Vitro Cellular
and Developmental Biology 24(5):487-490.

37. Schaeffer, W. I. 1990. Terminology Associated with Cell Tissue and Organ Culture, Molecular Biology and Molecular Genetics. In Vitro Cellular and Developmental Biology, 26:97-101.

38. Schaeffer, W. I., Stephen G. Simkins and B. J. Lamore 1990. A System Employing a Minimal Defined
Medium for the Selection of Tumorigenic Cells. In Vitro Cell and Developmental Biology 26:737-740.

39. Schaeffer, W. I. Terminology. In: Cell & Tisue Culture: Laboratory Procedures; J. B. Griffiths, A. Doyle and D. G. Newell Eds., John Wiley & Sons Limited. In Press.

40. Schaeffer, W. I., L. D. Olson, M. F. Barile and F. W. Sun. 1991. Analysis of Mycoplasma hyorhinis DNA in the Presence of Host Cells without Growing the Mycoplasma Axenically. J. Bact. 173:1382-1387.

41. Schaeffer, W. I. and R. Melamede. 1993. Fluorometric Quantitation of Broth-Cultured Mycoplasmas by Using Alkaline Ethidium Bromide. J. Clin. Microbiol. 31:1303-1307

42. Zavizion, B., M. Van Duffelen, W. Schaeffer and I. Politis. 1996. Establishment and Characterization of a Bovine Mammary Epithelial Cell Line with Unique Properties. In Vitro Cellular and Developmental Biol., 32:138-148.

43. Zavizion, B., M. Van Duffelen, W. Schaeffer and I. Politis. 1996. Establishment and Characterization of a BovineMammary Myoepithelial Cell Line. In Vitro Cellular and Developmental Biol., 32:149-158.

44. Zavizion, B., M. Van Duffelen, W. Schaeffer and I. Politis. 1996. Use of microinjection to generate an immortalized bovine mammary cell line with both epithelial and myoepithelial characteristics. Methods in Cell Science, 17(4), 271-282.

45. Dodson, M. V. and W. I. Schaeffer, 2000, Generation of viable cell-culture data. Methods in Cell Science, 22(1), 27.