University of Vermont
Dept. of Microbiology & Molecular Genetics
95 Carrigan Drive
220 Stafford Hall
Burlington, VT 05405
O: (802) 656-8503
F: (802) 656-5172
Ph.D. Microbiology Massachusetts Institute of Technology, 1983
M.S. Microbiology University of Vermont, 1978
A.B. Chemistry Middlebury College, 1975 (High Honors, cum laude)
Academic and Professional Experience:
1998-2003 Vice Provost for Research and Graduate Education, University of Vermont, Burlington, Vermont
1999-2000 Interim Dean of the Graduate College, University of Vermont, Burlington, Vermont
1996-present Professor of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont
1992-1996 Associate Professor of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont
1992-present Member, Vermont Cancer Center, 1992; 1998-2003, Governing Board
1988-1992 Assistant Professor of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont
1983-1988 Assistant Professor of Chemistry, Williams College, Williamstown, Massachusetts
1975-1976 Assistant in Chemistry, Middlebury College, Middlebury, Vermont
Professional Affiliations and Activities:
American Association for the Advancement of Science (1978 - present).
American Chemical Society (1975 - present).
American Society for Biochemistry and Molecular Biology (1992 - present).
American Society for Microbiology (1976 - present).
American Society of Gene Therapy (2000 - present).
International Society for Antiviral Research (2000 - present).
The RNA Society (1994 - present).
Honors and Awards:
Phi Beta Kappa, Middlebury College, 1975
National Science Foundation Graduate Fellowship, UVM and MIT, 1976 - 1979
National Institutes of Health Graduate Trainee, MIT, 1979 - 1983
Sigma Xi, MIT, 1983
Vermont Academy of Science and Engineering, 1998
Author or co-author of more than 80 peer-reviewed papers, 100 conference papers, and 125 invited research talks since 1992 on ribozymes, RNA processing, and RNA-protein interactions as well as in vitro selection, antiviral applications of ribozymes and targeted RNA cleavage.
Structure and mechanism of hairpin and hammerhead ribozymes
Ribozyme applications for antiviral therapy and functional genomics
Computational and biochemical approaches to RNA tertiary structure
In vitro selection and combinatorial approaches to ribozyme structure and activity