MR. BRIAR L. ALPERT (2006) pdf

Mr. Briar L. Alpert
Work Address:
BioTek Instruments, Inc.
Highland Park, Box 998,
Winooski, Vermont 05404-0998

Home Address:
271 Hills Point Road
Charlotte Vermont 05445

802-655-4040, Ext. 258/802-425-4020

BS Mechanical Engineering, University of Vermont 1983
MBA University of Vermont 1993

Professional Experience:
2000 - Present: President, BioTek Instruments, Inc.
1999 - 2000: President, DNI Nevada (a BioTek Subsidiary)
1995 - 2000: VP Operations, BioTek Instruments, Inc.
1990 - 1995: Project Manager, Integrated Systems Products, BioTek Instruments, Inc.
1988 - 1990: Manager of Assembly Operations, BioTek Instruments, Inc.
1986 - 1988: Manufacturing Engineer, BioTek Instruments, Inc.
1984 - 1986: Project Engineer, Pizzagalli Construction Co.

Notable Projects:
Program Manager for fully automated ELISA system.
Responsible for all BioTek domestic and international intellectual property including its acquisition, assertion and defense.


Negotiated and managed multiple BioTek financial structures including asset base financing, syndicated banking deals and international banking.
Organized and led multiple multimillion dollar domestic and international corporate acquisitions and divestitures including DNI Nevada Inc., Dale Technology Inc. and Kontron Instruments Inc.
Implemented multiple MRP (Material Requirement Planning), ERP (Enterprise Resource Planning) and CRM (Customer Relationship Management) systems.
Lead Multiple Strategic Planning Processes.
Lead multiple negotiations for technology transfer including Automated Fluorescence Microplate Spectrophotometer, Precision Nanoliter Dispenser and Software Data Reduction Modules

Technical-Scientific Accomplishments:
Achieved carryover specification of less than 1 part per million with non-disposable tips in a fully automated commercially qualified ELISA analyzer.
Controlled reagent and patient sample fluid movement with accuracy of 1% and coefficient of variation of 2% over a large dynamic range in a fully automated chemistry analyzer.
Development of the first high quality low-cost ELISA plate reader with powerful onboard data reduction software.
Evolved microplate instrumentation technology from single channel 96 well absorbance detection to multimode measurement techniques including Fluorescence Intensity, Time Resolved Fluorescence, Fluorescence Polarization, Glow and Flash Luminescence, UV-Vis Absorbance, FRET, TR-FRET, BRET, area scanning and spectral scanning in 96/384/1536 plate format.
Generated data reduction protocols, algorithms and database software for assay set up and data reduction of life science and analytical results.
Integration of an ultra low natural frequency centrifuge into a fully automated Agglutination system capable of blood typing and cross matching.
Development of optimal acceleration profiles for tight control of fluid moving mechanisms.
Development of truly universal 96/384 well microplate washer that allowed smooth transition for scientist to high-density plate format.

Member of Beta Gamma Sigma - Mechanical Engineering Honor Society

Public Service:
Charter Member and Director, Vermont Center for Emerging Technologies

Married to Susan Vigsnes, two daughters.
Hobbies: Physical Fitness, Running, Swimming, Biking, Triathlons Tennis, Golf, Boating