University of Vermont

The College of Arts and Sciences

Department of Psychological Science

John Hughes

Human Behavioral Pharmacology

John Hughes

John Hughes
Professor of Psychology
Professor of Psychiatry

  • B.S. Millsaps College, 1971
  • M.D. University of Mississippi Medical School, 1975
  • C.V. (PDF)
Phone: (802) 656-9610
Room: FAHC-UHC Room 3126


Faculty, Human Behavioral Pharmacology Laboratory

Faculty, Behavioral Pharmacology of Drug Dependence Training Program


Clinical, laboratory and epidemiological studies on tobacco cessation and on marijuana cessation. I have two NIH grants to study

  1. what daily events prompt cigarette smokers to decide to quit
  2. what methods daily marijuana users employ when they try to quit and how helpful are they
  3. whether stopping smoking makes smokers anhedonic; i.e. they enjoy pleasures less
  4. whether continuing medication after a smoker relapses helps them re-establish abstinence
  5. whether reducing smoking increases or decreases motivation to quit smoking


Vermont Center on Behavior and Health: The Vermont Center on Behavior and Health (VCBH) is an interdisciplinary center of research excellence committed to investigating relationships between personal behavior patterns (i.e., lifestyle) and risk for chronic disease and premature death.

Human Behavioral Pharmacology Laboratory (HBPL): This facility is located across the street from the Psychology Department and is the site for clinical and laboratory research.

Representative Publications

  • Hughes J, Rennard S, Fingar J, Talbott S, and Fagerstrom K. 2011a. Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: A randomized placebo-controlled trial. Nicotine & Tobacco Research, submitted 11/12/10 13:995-964.
  • Hughes J, and Callas P. (in press). Is delaying a quit attempt associated with less success? Nicotine and Tobacco Research.
  • Hughes J, Peters E, and Naud S. 2011b. Effectiveness of over-the-counter nicotine replacement therapy: A qualitative review. Nicotine & Tobacco Research 13:512-522.
  • Hughes J, Solomon L, Livingston A, Callas P, and Peters E. 2010. A randomized, controlled trial of gradual cessation (aided by NRT) vs. abrupt cessation of smoking. Drug Alcohol Depend 111:105-113.
  • Peters E, and Hughes J. 2010. Daily marijuana users with a history of alcohol abuse or dependence substitute alcohol during marijuana cessation. Drug Alcohol Depend 106:111-118.

Faculty and Staff Directory