SHERYL WHITE

Research Assistant Professor

Anatomy and Neurobiology

Ph.D., University of Vermont, 1992
Postdoctoral training, University of Vermont

Sheryl.White@uvm.edu

My general research interests are in gene structure, expression and regulation, with a focus on neural plasticity and developmental neurobiology. I utilize molecular biology techniques to explore factors which regulate neuron-specific genes.

My previous projects at the University of Vermont involved the identification and cloning of a novel myosin isoform, cloning and characterization of the rat smooth muscle myosin heavy chain and rat pituitary adenylate cyclase activating polypeptide promoters, cloning of chicken bmi, and analysis of neuropilin expression in rat smooth muscle. I plan to continue my work in neuropilins by investigating the factors responsible for tissue-specificity of neuropilin expression during development.

As director of the COBRE Neuroscience Molecular Biology Core Facility, I am involved in a wide variety of exciting neuroscience projects. My goal as director is to provide researchers with the most up to date techniques to assist them in attaining their research goals.

Higgins, L and SL White.  (2006)  Patterns of variation among distinct alleles of the Flag silk gene from Nephila clavipes.  Int. J. Biol. Macro. doi:10.1016/j.ijbiomac.2006.07.007.

Girard, BM, BA Young, TR Buttolph, SL White and RL Parsons (2006) Modulation of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) expression in explant-cultured guinea pig cardiac neurons.  Ann. N.Y.         Acad. Sci. 1070: 298-302. Abstract Full Text

Girard, B., B. Young, T. Buttolph, S. White and R. Parsons (2007)  Regulation of neuronal pituitary adenylate-cyclase-activating polypeptide (PACAP) expression during culture of guinea pig cardiac ganglia.  Neuroscience 146: 584-593. Full Text

Cutroneo, KR, SL White, TR Buttolph, G. Allison and HP Ehrlich (2007)  Phenotypic expression of human hepatoma cells in culture.  J. Cell Biochem.  100: 1081-5. Abstract Full Text

Cutroneo, KR, SL White, SH Phan and HP Ehrlich (2007) Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression.  J. Cell. Physiol. 211:585-9. Abstract Full Text

Bouffard, NA, KR Cutroneo, GJ Badger, SL White, TR Buttolph, HP Ehrlich, D Stevens-Tuttle and HM Langevin (2008) Tissue stretch decreases soluble TGF-beta1 and type-1 procollagen in mouse subcutaneous connective tissue: evidence from ex vivo and in vivo models.  J. Cell Physiol. 214: 389-395. Abstract Full Text

Lowey, S, LM Lesko, AS Rovner, AR Hodges, SL White, RB Low, M Rincon, J Gulick and J Robbins (2008) Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.  J. Biol. Chem. 283 (29): 20579-89. Abstract Full Text

Lok, CN, HP Ehrlich, SL White, TR Buttolph, KR Cutroneo and JF Chiu (2008) Oligodeoxynucleotide decoy therapy blocks type 1 procollagen transcription and the prolyl hydroxylase beta subunit translation.  J. Cell. Biochem. 103(4): 1066-76. Abstract Full Text

Grafer, CM, R Thomas, L Lambrakos, I Montoya, SL White and LM Halvorson (2009) GnRH stimulates expression of PACAP in the pituitary gonadotropes via both the PKA and PKC signaling systems.  Mol. Endocrinol. 23(7): 1022-32. Abstract Full Text

Armbruster, P., SL White, J Dzundza, J Crawford and X Zhao (2009) Identification of genes encoding atypical odorant-binding proteins in Aedes albopictus (Diptera: Culicidae).  J. Med. Entomol. 46(2): 271-280. Abstract

Linden, DR, SL White, EM Brooks and GM Mawe (2009) Novel promoter and alternate transcription start site of the human serotonin reuptake transporter (SERT) in intestinal mucosa.  Neurogastroenterol. Motil. 21(5): 534-541. Abstract Full Text

Rosensteel, SM, RP Wilson, SL White and HP Ehrlich (2010) COL1A1 oligodeoxynucleotides decoy: Biochemical and morphological effects in an acute wound repair model.  Exp. Mol. Pathology 89: 307-313. Abstract Full Text