Professor of Medicine
Ph.D., University of New Mexico, 1982, Pathology-Immunology
Postdoctoral training, University of New Mexico School of Medicine, 1982-1984, Pathology
The major focus of the research effort in my laboratory is the identification and characterization of non-classical immune response genes controlling susceptibility and resistance to immunopathologically mediated diseases. These include models of multiple sclerosis in mice such as Theiler’s murine encephalomyelitis induced demyelination and experimental allergic encephalomyelitis. Using forward genetics, we have identified quantitative trait loci (QTL) that govern phenotypic variation in these models and identified factors that influence the magnitude of demyelination and neurodegeneration observed in these models.
I am also interested in the Genetics of Sexual Behavior. My lab was one of the first to show that male typical sexual behavior is genetically controlled and that it appears to be related to the developmental effects of estrogen. We know that estrogen regulated responses are genetically controlled and plan to map the QTL controlling the phenotypic variation in male typical sexual behavior in rats.
Last modified October 10 2011 02:37 PM