Neuroscience Graduate Program Faculty
Rodney C. Scott, MD, PhD
Professor and Vice-Chair for Research, Department of Neurological Sciences
- MD University of Zimbabwe
- PhD University of London
Contact InformationPhone: (802) 656-4588
Office Hours: by appointment
Office Location: Stafford 118D, 95 Carrigan Drive, Burlington, VT
I straddle the interface between basic and clinical science and have developed skills in both domains. This has enabled me to carry out and lead multidisciplinary research projects, with scientific findings that potentially have major clinical implications. My research focuses on the etiology and treatment of pediatric learning disorders. I am particularly interested in distinguishing cognitive deficits due to developmental anomalies of the brain from deficits caused by epilepsy driven by abnormal development. The clinical framework of my research is from my broad background in child neurology and, over the last decade, from my specialty in pediatric epilepsy. My laboratory combines studies in animals using single unit and oscillatory activity as markers of the network together with my work with children suffering from epilepsy. In addition, my work involves transdisciplinary collaborations with computer scientists, educators, imagers, statisticians, and electrophysiologists.
Kleen, J.K., Scott, R.C., Holmes, G.L., Roberts, D.W., Rundle M.M., Testorf, M. Lenck-Santini, P.P. Jobst, B.C. (2013). Hippocampal lnterictal Epileptiform Activity Disrupts Cognition in Humans. Neurology (in press)
Martinos MM, Yoong M, de-Hann M, Scott RC. (2013). The effects of convulsive status epilepticus on early development; a prospective cohort study. Epilepsia (in press)
Scott RC, Holmes GL. (2012). Before Epilepsy Unfolds: Opening up the potassium door in neonatal seizures. Nat Med. Nov;18(11):1624-5.
Hernan AE, Holmes GL, lsaev D, Scott RC, lsaeva E. (2012). Altered short-term plasticity in the prefrontal cortex after early life seizures. Neurobiol Dis; 50(2):120-126.
Bender AC, Natala H, Holmes GL, Scott RC, Lenck-Santini PP. (2013). Focal Scn1a knockdown induces cognitive impairment without seizures Neurobiol Dis; [Epub ahead of print]
Eltze CM, Chong WK, Cox T, Whitney A, Cortina-Borja M, Chin RF, Scott RC, Cross JH. (2013). A population-based study of newly diagnosed epilepsy in infants. Epilepsia; 54(3): 437-445
Martines MM, Yoong M, Scott RC, de-Haan M. (2012) Evidence for impaired recognition memory following prolonged febrile seizures. Brain; 135(10):3153-64.
Tyler AL, Mahoney JM, Richard GR, Holmes GL, Lenck-Santini PP, Scott RC (2012). Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats. J Neurosci; 32(33):11365-76.
Scott RC, Holmes GL (2012). Febrile seizures and the wandering granule cell. Nat Med; 18(8):1180-2.
D'Argenzio L, Colonnelli MC, Harrison S, Jacques TS, Harkness W, Scott RC, Cross JH (2012). Seizure outcome after extratemporal epilepsy surgery in childhood. Dev. Med Child Neural; 54(11): 995-1000
Lazow SP, Thadani VM, Gilbert KL, Morse RP, Bujarski KA, Kulandaivel K, Roth RM, Scott RC, Roberts DW, Jobst BC (2012). Outcome of frontal lobe epilepsy surgery. Epilepsia; 53(10): 1746- 55.
Kahlenberg CA, Fadul CE, Roberts DW, Thadani VM, Bujarski KA, Scott RC, Jobst BC (2012). Seizure prognosis of patients with low-grade tumors. Seizure; 21(7):540-5.
Banu SH, Khan NZ, Hossain M, Ferdousi S, BoydS, Scott RC, Neville B (2012). Prediction of seizure outcome in childhood epilepsies in countries with limited resources: a prospective study Dev Med Child Neurol; 54(10): 918-24
Colonnelli MC, Cross JH, Davies S, D'Argenzio L, Scott RC, Pickles A, Hannan S, Harkness W, Heyman I (2012). Psychopathology in children before and after surgery for extratemporal lobe epilepsy. Dev Med Child Neurol.;54(6}:521-6.
Duffy B, Choy M, Riegler J, Wells JA, Scott RC, Lythgoe MF (2012). Imaging Seizure-Induced Inflammation using an Antibody Targeted Iron Oxide Contrast Agent. Neuroimage; 60(2):1149-55.
Last modified September 30 2013 01:22 PM