Publications

Publications from UVM:

• Synthesis of Demissidine by a Ring Fragmentation 1,3-Dipolar Cycloaddition Approach

Zhang, Z.; Giampa, G.M.; Draghici, C.; Huang, Q.; Brewer, M. Org. Lett. 2013, 15(9), 2100-2103 [Supporting Information]

 

• Stereoelectronic Effects in the Fragmentation of γ-Silyloxy-β-hydroxy-α-diazocarbonyl Compounds

Jabre, N.D.; Brewer, M., J. Org. Chem. 2012, 77(21), 9910-9914 [Supporting Information]

 

• Stereospecific Intramolecular C–H Amination of 1-Aza-2-azoniaallene Salts

Bercovici, D.A.; Brewer, M. J. Am. Chem. Soc. 2012, 134 (24), 9890-9893  [Supporting Information]

       

• Iodine(III)-Mediated Bicyclic Diazenium Salt Formation

Al-Bataineh, N.Q.; Brewer, M. Tetrahedron Lett. 2012, 53 (40), 5411-5413 

 

• A Ring Fragmentation Approach to Medium-Sized Cyclic 2-Alkynones

Tsvetkov, N.P.; Bayir, A.; Schneider, S.; Brewer, M. Org. Lett. 2012, 14 (1), 264-267  [Supporting Information]

   

• Synthetic Approaches to Bicyclic Diazenium Salts

Wyman, J.; Javed, M.I.; Al-Bataineh, N.; Brewer, M. J. Org. Chem. 2010, 75 (23), 8078-8087  [Supporting Information]

 

• Preparation of Tethered Aldehyde Ynoates and Ynones by Ring Fragmentation of Cyclic γ-Oxy-β-hydroxy-α-diazo Carbonyls

Published as a Featured Article

Bayir, A.; Draghici, C.; Brewer, M. J. Org. Chem. 2010, 75 (2), 296–302  [Supporting Information]

 

• An Efficient Synthetic Approach to Polycyclic 2,5-Dihydropyrroles from α-Silyloxy Ketones

Draghici, C.; Huang, Q.; Brewer, M. J. Org. Chem. 2009, 74 (21), 8410–8413. [Supporting Information]

 

• Synthesis of Fused and Bridged Bicyclic Diazenium Salts by Intramolecular Cycloaddition

Javed, M.I.; Wyman, J.M.; Brewer, M., Org. Lett. 2009, 11(10), 2189–2192. [Supporting Information]

 

• Lewis acid promoted carbon-carbon bond cleavage of γ-silyloxy-β-hydroxy-α-diazoesters

Draghici, C.; Brewer, M., J. Am. Chem. Soc. 2008, 130(12), 3766-3767. [Supporting Information]

 

• Chlorodimethylsulfonium Chloride-Mediated Formation of Phenyl-α-chloroazoalkanes

Wyman, J.M.; Jochum, S.; Brewer, M., Synth. Comm. 2008, 38(21), 3623-3630.

 

• Diphenyldiazomethane

Javed, M.I., Brewer, M., Organic Syntheses 2008, 85, 189-195.

  

• Diazo Preparation via Dehydrogenation of Hydrazones with "Activated" DMSO

Javed, M.I., Brewer, M. Org. Lett. 2007, 9, 1789-1792. [Supporting Information]

 

• Conversion of hydrazones to alkyl chlorides under Swern oxidation conditions

Brewer, M. Tetrahedron Lett. 2006, 47, 7731-7733.

 

Publications from Prior Work:

• Selective Cell Adhesion Inhibitors: Barbituric Acid Based α4β7MAdCAM Inhibitors

Harriman, G.C.; Brewer, M.; Bennett, R.; Kuhn, C.; Bazin, M.; Larosa, G.; Skerker, P.; Cochran, N.; Gallant, D.;

Baxter, D.; Picarella, D.; Jaffee, B.; Luly, J.R.; Briskin, M.J. Bioorg. Med. Chem. Lett. 2008, 18(7), 2509.

• Facile Degradative Lactonization of Gln-Arg and Gln-Phe Hydroxyethylene Dipeptide Derivatives

Haug, B.E., Brewer, M., Rich, D.H. J. Pept. Res., 2005, 65(1), 77-83.

 

• Synthesis of a Tripeptide Derivative Containing the Gln-Arg Hydroxyethylene Dipeptide Isostere

Brewer, M., James, C.A., Rich, D.H. Org. Lett. 2004, 6 (25), 4779-4782. [Supporting Information]

 

• Design and Synthesis of Substrate-Based Inhibitors of Botulinum Neurotoxin Type B Metalloprotease

Oost, T., Sukonpan, C., Brewer, M., Goodnough, M., Tepp, W., Johnson, E.A., Rich, D.H. Biopolymers 2003, 71(6), 602-619.

 

• Sequencing Hydroxyethylamine containing peptides via Edman Degradation

Brewer, M., Oost, T., Sukonpan, C., Pereckas, M., Rich, D.H. Org. Lett. 2002, 4(20), 3469-3472. [Supporting Information]

 

• Synthesis of a Tripeptide Derivative Containing the Phe-Arg Hydroxyethylene Dipeptide Isostere

Brewer, M., Rich, D.H. Org. Lett. 2001, 3(6), 945-948. [Supporting Information]