GYNECOLOGIC PATHOLOGY

Slide 311: Endometrial Carcinoma

SLIDE 311: Endometrial Carcinoma
Case History:
Ms. Bell, a 71 year old retired telephone operator, presents to her PMD
with a five-month history of irregular postmenopausal bleeding. She has
not been taking her hormone replacement therapy. On exam, she is moderately
obese, appears pale. A vaginal exam shows no obvious local source for the
bleeding. Lab studies show a hematocrit of 34, normal differential and platelet
count.
A D&C produces bulky uterine curettings. Histological examination
shows severe cytological and architectural atypia of the endometrium. Ms.
Bell had a hysterectomy and bilateral salpingo-oophorectomy. The uterine
cavity is filled with focally necrotic, pale, friable tumor that does not
extend through the serosal surface.

Microscopic Description
Questions and Answers

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