University of Vermont

College of Nursing and Health Sciences
Sten Holm

Sten Holm, PhD

Adjunct Professor

Sten Holm

Office: 305 Rowell Building
Phone: (802) 656-3252
Email: Sten.Holm@uvm.edu

Areas of Interest
  • Nutrition of the intervertebral disc
  • Transport and metabolism
  • Pathophysiology of intervertebral disc degeneration
  • Experimental instability of the lumbar spine
  • Mechanical considerations of the intervertebral disc and vertebral body interactions
  • Pathoanatomical experimental studies of the craniomandibular joint and masticatory muscles
  • Sensorimotor control of the lumbar spine
  • Physiological responses after experimental nerve root compression
  • Neuromuscular aspects concerning control of the lumbar motion segment
  • Neurophysiology of the lumbar muscles
  • Reflex systems and corticomotor excitability
  • Growth factors and bone remodelling in intervertebral disc degeneration
Education

Professor of Experimental Surgery, University of Gothenburg, Gothenburg, Sweden, 2003
Associate Professor, University of Gothenburg, Gothenburg, Sweden, 1982
PhD, University of Gothenburg, Gothenburg, Sweden, 1980

Selected Publications
Scientific Presentations

Over 250 scientific presentations (published abstracts) at international conferences in the fields of orthopaedics, surgery, odontology, physiology, zoology, biochemistry and rehabilitation.
More than 80 presentations as an invited guest lecturer, both national and international.

Published Book Chapters

Indahl A, Holm S. The sacroiliac joint, sensory-motor control and pain. In: Movement, stability and lumbopelvic pain. Ed. Vleeming A. Churchill Livingstone, 2007.

Holm S, Indahl A. Sensorimotor control of the lumbar spine. In: The Lumbar Spine. 3rd ed. Eds. Herkowitz H, Dvorak J, Bell G, Nordin M, Grob D. Lippincott, Williams & Wilkins, 2004.

Kaigle Holm AM, Holm SH. Biomechanical considerations of disc degeneration. In: The Lumbar Spine. 3rd ed. Eds. Herkowitz H, Dvorak J, Bell G, Nordin M, Grob D. Lippincott, Williams & Wilkins, 2004.

Holm S. Nutritional and pathophysiological aspects of the lumbar intervertebral disc. In: The Lumbar Spine. Eds. Wiesel SW, Weinstein JN, Herkowitz H, Dvorak J, Bell G. WB Saunders, 1996.

Rydevik B, Holm S. Pathophysiology of the intervertebral disc and adjacent neural structures. In: Intervertebral disc disease and back pain. Eds. Rothman and Simeone, 1990.

Ström D, Carlsson GE, Holm S. Metabolic alterations in a contracting masticatory muscle in response to electrical stimulation. In: Electromyography of Jaw Reflexes in Man. Eds. Van Steenberghe D, De Laat A, 1989.

Holm S, Urban J. The intervertebral disc: factors contributing to its nutrition and matrix turnover. In: Joint Loading. Ed. Helminen HJ, 1987.

Urban J, Holm S. Intervertebral disc nutrition as related to spinal movements and fusion. In: Tissue nutrition and Viability. Ed. Hargens A, 1986.

Myrhage R, Lundborg G, Rydevik B, Holm S, Hansson H-A, Rank F. Nutrition and healing of flexor tendons in synovial environments. In: Clinical Applications of Biomaterials. Eds. Lee AJC, Albrektsson T, Brånemark P-I, 1982.

Published Refereed Journal Articles

Mackiewicz Z, Salo J, Konttinen YT, Kaigle Holm A, Indahl A, Pajarinen J, Holm S. Receptor activator of nuclear factor kappa B ligand in an experimental intervertebral disc degeneration. Clin Exp Rheumatol 27:299-306, 2009.

Kawchuk GN, Kaigle Holm AM, Ekström L, Hansson T, Holm S. Bulging of the inner and outer annulus during in vivo loading of normal and degenerated discs.J Spinal Disord & Tech, 22(3):214-8, 2009.

Holm S, Mackiewicz A, Holm AK, Konttinen YT, Kouri VP, Indahl A, Salo J. Pro-inflammatory, pleiotropic, and anti-inflammatory TNF-alpha, IL-6 and IL-10 in experimental porcine intervertebral disc degeneration. Vet Pathol 46:1292-300, 2009.

Hodges PW, Galea MP, Holm S, Kaigle Holm A. Corticomotor excitability of back muscles is affected by intervertebral lesion. Eur J Neuroscience 29:1490-50, 2009.

Salo J, Kaigle Holm A, Indahl A, Mackiewicz Z, Sukura A, Holm S, Jämsen E, Konttinen Y. Expression of vascular endothelial growth factor receptors coinicide wth blood vessel in-growth and reactive bone remodelling in experimental intervertebral disc degeneration. Clin Exp Rheumaatol 26:1018-26, 2008.

Salo J, Mackiewicz Z, Indahl A, Konttinen Y, Kaigle Holm A, Sukura A, Holm S. Plasmin-matrix metalloproteinase cascades in experimental intervertebral disc degeneration in pig. Spine 33(8):839-44, 2008.

Holm S, Ekström L, Kaigle Holm A, Hansson T. Intradiscal pressure in the degenerated porcine intervertebral disc. Vet Comp Orthop Traumatol 20(1):29-33, 2007.

Holm S, Baranto A, Kaigle Holm A, Ekström L, Swärd L, Hansson T, Hansson H-A. Reactive changes in the adolescent porcine spine with disc degeneration due to endplate injury. Vet Comp Orthop Traumatol 20(1):12-7, 2007.

Ihlebaek C, Hansson TH, Laerum E, Brage S, Eriksen HR, Holm SH, Svendsrod R, Indahl A. Prevalence of low back pain and sickness absence: a “borderline” study in Norway and Sweden. Scand J Public Health 34:555-8, 2006.

Hodges P, Kaigle Holm A, Hansson T, Holm S. 2006 Internationl Society for the Study of the Lumbar Spine Prize. Rapid atrophy of the lumbar multifidus follows experimental disc or nerve root injury. Spine 31(25):2926-33, 2006.

Holm S, Kaigle Holm A, Ekström L, Karladani A, Hansson T. Experimental disc degeneration due to endplate injury. J Spinal Disord & Tech 17(1):64-71, 2004.

 

Last modified June 23 2014 03:34 PM