Faculty - Bryan Ballif

Bryan Ballif

Bryan Ballif,

Associate Professor
  • Ph.D. (2001) Harvard University, Department of Cell Biology, Harvard Medical School;
  • Postdoctoral Fellow (2001 - 2003) Division of Basic Sciences, Fred Hutchinson Cancer Research Center;
  • Postdoctoral Fellow (2003 - 2006) Department of Cell Biology, Harvard Medical School;
  • Assistant Professor (2006-2012) Department of Biology, University of Vermont;
  • Co-Director Vermont Genetics Network Proteomics Facility (2008 - 2011);
  • Co-Director Immuno-COBRE Proteomics Core (2011 - );
  • Associate Professor (2012 - ) Department of Biology, University of Vermont
Area of expertise

Signal transduction, proteomics, neuroscience

Contact Information
Email: Bryan Ballif

Office Hours: Wednesdays, 9:30-11:30
Marsh Life Science Building, Rm 311
Phone: (802) 656-1389
Website: Ballif Lab

Research

Research in the Ballif lab is primarily focused on elucidating molecular mechanisms of signal transduction with two majoremphases: (A) genetically-defined signaling pathways regulating vertebrate brain development and (B) core signalingpathways regulating cell proliferation, growth andsurvival. In addition to biochemical and cell biological approaches, we employ mass spectrometry-based proteomics as a primary tool to identify and quantitatively monitor proteins, their modifications and their interactions with other proteins following acute signal administration or across developmental stages. We are also using zebrafish, drawing on the expertise of our sister lab headed by Alicia Ebert, as an organismalmodel system to study signaling pathways regulatingdevelopment, particularly neuronal positioning.

A second focus of our work involves developing and applying proteomic methodology to advance diverse lines of biological inquiry, some of which have had little to no interface with proteomics. This makes these projects both exciting and challenging. These collaborative projects range from the identification of novel human blood group antigens; to the identification of host proteins that interact with arenavirus proteins; to targeted proteomic characterizations of wasps, pitcher plant ecosystems, ants, fruit flies, unicellular ciliates and parasitic protozoa.

Publications:

Proteomic and Signaling Studies of the Brain or Cell Migration

Signaling Studies in Cell Survival / DNA Damage / Cell Growth and Proliferation

Protein / Proteomic Studies in Immunobiology / Transfusion Science

Proteomic / Protein / Phylogenetic Studies in Evolution and Ecology

Additional Diverse Proteomic / Protein Studies


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