Faculty - Alicia Ebert
Alicia Ebert, Assistant Professor
- PhD, Colorado State University, 2008
- University of Wyoming, 2001-2002, Research Assistant, Department of Molecular Biology
- University of Colorado Health Sciences Center, 2002-2003, Research Assistant, Department of Neuroscience
- University of Calgary, 2008-2012, Postdoctoral Fellow, Department of Cell Biology and Anatomy
- University of Vermont, 2012 - , Assistant Professor, Department of Biology
- CV (PDF)
Area of expertise
Contact InformationEmail: Alicia Ebert
Office Hours: Thurs 9:00-11:00
Marsh Life Science Building, Rm 313
Phone: (802) 656-0458
My research focuses on two aspects of zebrafish eye development. The eyes develop from forebrain tissues and must migrate bilaterally to take up their final position. I am interested in what mechanisms/molecules are involved in maintaining eye tissue cohesion as they undergo elegant movements of morphogenesis and migration. I have discovered a novel role for signaling molecules previously known for their roles in axon guidance, semaphorins and plexins, in tissue cohesion of the developing eye.
The other focus of my research involves fibroblast growth factor (FGF) signaling in patterning the retinal vasculature and maintenance of Retinal Ganglion Cell (RGC) morphogenesis and survival. Loss of FGF8a or inhibition of the FGF receptors (FGFRs) results in embryos with fewer RGCs and small optic nerves. We are uncovering a role for FGF signaling in maintenance and survival of RGCs by regulating vascularization of the retina.
- Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilknson B, Lounsberry K, Guo M, Francklyn CS. 2015. Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor. Nature Scientific Reports Aug 14;5:13160.
- Ebert AM, Childs SJ, Hehr C, Cechmanek PB, McFarlane S. 2014. Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion. Development 141(12):2473-2482.
- Rohs P, Ebert AM, Zuba A, McFarlane S. 2013. Neuronal expression of fibroblast growth factors in zebrafish. Gene Expression Patterns. Jul 9;13(8):354-361.
- Chernyavskaya Y, Ebert AM, Milligan E, Garrity DM. 2012. Voltage-gated calcium channel CACNB2 (b2.1) protein is required in the heart for control of cell proliferation and heart tube integrity. Dev Dyn. Apr;241(4):648-62.
- Ebert AM, Lamont RE, Childs SJ, McFarlane S. 2012. Neuronal expression of class 6 semaphorins in zebrafish. Gene Expression Patterns. Feb2;12(3-4)117-122.
- Ebert AM, McAnelly CA, Handschy AV, Mueller RL, Horne WA, Garrity DM. 2008. Genomic organization, expression and phylogenetic analysis of Ca2+ channel β4 (CACNB4) genes in thirteen vertebrate species. Physiological Genomics. Oct 8;35(2): 133-44.
- Ebert AM, McAnelly CA, Srinivasan A, Muller RL, Garrity DB, Garrity DM. 2008. The calcium channel beta2 (CACNB2) subunit repertoire in teleosts. BMC Molecular Biology. 9(38).
- Ebert AM, McAnelly CA, Srinivasan A, Linker JL, Horne WA, Garrity DM. 2008. Ca2+ Channel-independent requirement for MAGUK-family CACNB4 genes in initiation of zebrafish epiboly. Proc. Natl. Acad. Sci. USA 105(1); 198-203.
- Ebert AM, Hume GL, Warren KS, Cook NP, Burns CG, Mohideen MA, Siegal G, Yelon D, Fishman MC, Garrity DM. 2005. Calcium extrusion is critical for cardiac morphogenesis and rhythmicity in embryonic zebrafish hearts. Proc. Natl. Acad. Sci. USA 102(49); 17705-17710.
- Sara Helms Cahan
- Ingi Agnarsson
- Bryan Ballif
- Alison K. Brody
- Alicia Ebert
- Charles J. Goodnight
- Nicholas J. Gotelli
- Brent L. Lockwood
- Brandon Ogbunu
- Melissa Pespeni
- Lori Stevens
- Judith Van Houten
- Jim O. Vigoreaux
Research Assistant Professors, Associates & Affiliates
- Molly Coseno (e-mail)
- Laura May-Collado
- Andrew Mead (e-mail)
- John Mitchell (e-mail)
- Megan Valentine (e-mail)
- Sarah Wittman (e-mail)
- Amanda L. Yonan (e-mail)
- William Ardren (e-mail)
- Lionel Arnaud (e-mail)
- Eric Buel
- Patricia Dorn
- Jeffrey Freeman
- Karen Hinkle
- David Lucero
- Ellen Martinsen
- Maria Carlota Monroy
- Michael Romano
- Steve Shapiro
- Charles Woods (e-mail)