All animal research at the University of Vermont is conducted with appropriate oversight:
- UVM holds an Animal Welfare Assurance from the Office of Laboratory Animal Welfare, an office of the National Institutes of Health, and adheres to all the requirements of the Health Research Extension Act of 1985 (Public Law 99-158).
- UVM is registered as a Research Facility under the U.S. Animal Welfare Act (7 USC 2131) and adheres to all of the requirements of the Act as enforced by the United States Department of Agriculture.
- A USDA Veterinary Animal Welfare Officer makes an unannounced visit to UVM at least annually, at which time the USDA veterinarian closely scrutinizes:
- Veterinary care of animals and medical records
- Animal husbandry and observation, including documented daily care on weekends and holidays
- Maintenance of the facilities, including construction, management and operation, sanitation, and social and environmental conditions for the animals
- Records of deliberations by the IACUC, including documented searches for alternatives to animal use
- As required by the Public Health Service policy and USDA, the UVM Institutional Animal Care and Use Committee (IACUC) provides close scrutiny, operating under guidelines established by the Guide for the Care and Use of Laboratory Animals. In the review of scientific protocols utilizing animals, the IACUC looks for evidence that the Principal Investigator has adhered to the principles of "the 3 R's" (William Russell & Rex Burch): Replacement, Refinement, and Reduction.