University of Vermont

University of Iowa and Hemostasis & Thrombosis Society Honor Mann’s Research Achievements

Professor of Biochemistry Kenneth Mann, Ph.D.  (Photo by Mario Morgado)
Professor of Biochemistry Kenneth Mann, Ph.D. (Photo by Mario Morgado)

Recognized as one of the world’s most foremost authorities on blood coagulation, Kenneth Mann, Ph.D., professor of biochemistry, was recently honored by both the Hemostasis & Thrombosis Research Society and his graduate school alma mater, the University of Iowa Carver College of Medicine.

In May 2012, Mann was presented with the 2012 Hemostasis & Thrombosis Research Society Lifetime Achievement Award, honoring his distinguished career and outstanding contributions to the field of blood clotting at the organization’s first Thrombosis and Hemostasis Summit of North America in Chicago, Ill. Mann’s nomination for the award cited his impact as an investigator – including his work to elucidate the pathways of thrombin formation and development of assays for many clotting factors – as well as his impact as an educator who trained numerous scientists who went on to lead their own laboratories.

A 1967 Ph.D. alumnus of the University of Iowa (UI) Carver College of Medicine, Mann was presented with the Distinguished Alumni Award on June 8, 2012 at the College’s Medical Alumni Reunion. At UI, Mann worked in the laboratory of the late Carl Vestling, former professor and chair of biochemistry, and then trained as a postdoctoral fellow with the late Charles Tanford, a former UI faculty member, at Duke University. He then joined the faculty at the University of Minnesota and Mayo Clinic, and in 1984, was recruited to the University of Vermont as chair of biochemistry, a position he held for 21 years. The UI award acknowledges Mann as one of the world’s foremost authorities on coagulation, based on his studies in protein chemistry and the biochemistry of blood clotting, and recognizes his work — including more than 500 published papers and 22 research patents over forty years — and contributions to the scientific understanding of the mechanisms and processes involved in blood clot formation. Specifically, the award honors the impact of Mann’s discoveries of factor V and major contributions to the dissection of vitamin K-dependent coagulation enzymes, which not only shed light on the normal, essential processes in clot formation and pathological states in acquired and congenital thrombotic and hemorrhagic diseases, but led to improved procedures for diagnosis and therapeutic interventions in bleeding and clotting disorders.

These two new honors are additions to a long list of recognition for Mann. In 2011, he was named a Distinguished Scientist by the American Heart Association (AHA). He is also the recipient of the Established Investigator, Sol Sherry and Special Recognition Awards from the AHA, the E. Donnall Thomas Prize and Stratton Medal from the American Society of Hematology, the Grant Medal from the International Society of Thrombosis and Hemostasis, and the Henri Chaigneau Prize from the Association Française des Hémophiles. He is a UVM University Scholar, member of the Vermont Academy of Science and Engineering, and received the Distinguished Alumnus of the Mayo Foundation Distinguished Career Award for Contribution to Hemostasis.

(Components of this article were adapted from a posting on the University of Iowa Biochemistry Blog.)