Photo Credits

Scanning electron micrograph of a mouse bronchial epithelial cell. Image courtesy of Michele von Turkovich, UVM Microscopy Imaging Center.
Confocal immunofluorescence image of a section through mouse aorta. Macrophages are stained green, actin red, and DNA blue. Image courtesy of Marilyn Wadsworth, UVM Microscopy Imaging Center; sample provided by Dr. Burt Sobel, Department of Medicine.
A canine kidney cell infected with Cryptosporidium parvum.  Confocal microscopy was used to visualize the parasite (green), and both the parasite and host cell nuclei (blue).  Image by Kovi Bessoff, MD, Ph.D. student rotating in the Huston lab.
Crystals of Methanocaldococcus janischii 8-oxoguanine DNA glycosylase. Image by Fred Faucher, postdoc in the Doublié lab. See Faucher F., et al. (2009) Structure 17:703-12.
Thymine glycol base pairs with adenine and maintains the same minor groove interactions as a canonical Watson Crick base pair. Image by Pierre Aller, postdoc in the Doublié lab. See Aller P. et al., (2007) PNAS 104:814-818.
A beta hairpin loop affects the switching of the primer strand from the polymerase to the exonuclease active site of RB9 DNA polymerase. Image by Pierre Aller & Matt Hogg, postdocs in the Doublié & Wallace labs. See Hogg M., Aller P., et al. (2007) J. Biol. Chem. 282:1432-1444.
Diffraction pattern of CFIm25, a pre-mRNA 3’-end processing factor. Image by Qin Yang, graduate student in the Doublié lab.
Enzymes of the base excision repair pathway repair oxidative DNA damage.

Image by Fred Faucher, postdoc in the Wallace lab.

A human fibroblast cell infected with Toxoplasma gondii. Fluorescence microscopy was used to visualize the nuclei of the parasites and host cells (blue), the parasite plasma membrane (red), and the parasite dense granules (light green).  Image by Mike Wichroski, graduate student in the Ward lab.
The position of a DNA lesion in chromatin DNA can affect the ability of a DNA glycosylase to excise the damaged base. Image by Ian Odell, graduate student in the Pederson lab.
A thymine glycol-adenine base pair captured in the active site of a replicative DNA polymerase. Image by Pierre Aller, postdoc in the Doublié lab. See Aller P. et al., (2007) PNAS 104:814-818.
Rat cerebral artery visualized by immunofluorecence miscrocopy using an antibody against the protein PGP 9.5. Image courtesy of Nicole Bishop, UVM Microscopy Imaging Center; sample provided by Dr. Marilyn Cipolla, Departments of Neurology and Pharmacology.
Scanning electron micrograph of Streptococci. Image courtesy of Michele von Turkovich, UVM Microscopy Imaging Center; sample provided by Dr. Grace Spatafora (Middlebury College).
Crystal structure of Methanocaldococcus janischii 8-oxoguanine DNA glycosylase in complex with 8-oxoG. Image by Fred Faucher, postdoc in Doublié lab.
  • What our students have to say...

    The MMG department is without question one of the best programs offered at UVM. I switched from biochemistry to molecular genetics at the end of my first semester of freshman year and it's the best decision I could have made for my undergraduate career. I feel like the specificity of the MMG program allowed me to really develop my interests and provide me with a direction in my studies that other majors can't provide. The MMG curriculum offers a variety of classes that appeal to a wide range of interests, from molecular cloning to mammalian cell culture to clinical microbiology. Although the classes are challenging, teachers and classmates are always happy to help. The small class sizes have allowed me to build relationships with my teachers and classmates and form life-long friendships. Since we’re such a small major, whenever you meet a fellow MMGer on campus you immediately form a bond! The professors make an effort to get to know you as an individual and they are incredibly supportive and helpful. They'll help you with anything from homework to deciding which classes to take. They will do anything to make sure you succeed. In MMG you'll have the opportunity to explore fascinating aspects of microbiology and molecular genetics and learn valuable skills for success after college. You'll also have a great time doing it! I feel like the knowledge and experience I've gained over the last few years has not only prepared me for a career in science, but sets me above fellow job and graduate school applicants. Being an MMGer has been an incredible experience for me. I'm so grateful to all of the faculty and classmates that have made my 4 years here so wonderful!

    Keri (Molecular Genetics), graduated 2015
Seminar
A Direct Role for Small Molecules and Anti-pili Antibodies in Inhibiting Diarrheal Diseases by Esther Bullitt

Wed February 1st, 2017 at 9:30 AM
HSRF 400

Seminar
TBA by Thomas Silhavy

Wed March 8th, 2017 at 9:30 AM
HSRF 300