Photo Credits

Scanning electron micrograph of a mouse bronchial epithelial cell. Image courtesy of Michele von Turkovich, UVM Microscopy Imaging Center.
Confocal immunofluorescence image of a section through mouse aorta. Macrophages are stained green, actin red, and DNA blue. Image courtesy of Marilyn Wadsworth, UVM Microscopy Imaging Center; sample provided by Dr. Burt Sobel, Department of Medicine.
A canine kidney cell infected with Cryptosporidium parvum.  Confocal microscopy was used to visualize the parasite (green), and both the parasite and host cell nuclei (blue).  Image by Kovi Bessoff, MD, Ph.D. student rotating in the Huston lab.
Crystals of Methanocaldococcus janischii 8-oxoguanine DNA glycosylase. Image by Fred Faucher, postdoc in the Doublié lab. See Faucher F., et al. (2009) Structure 17:703-12.
Thymine glycol base pairs with adenine and maintains the same minor groove interactions as a canonical Watson Crick base pair. Image by Pierre Aller, postdoc in the Doublié lab. See Aller P. et al., (2007) PNAS 104:814-818.
A beta hairpin loop affects the switching of the primer strand from the polymerase to the exonuclease active site of RB9 DNA polymerase. Image by Pierre Aller & Matt Hogg, postdocs in the Doublié & Wallace labs. See Hogg M., Aller P., et al. (2007) J. Biol. Chem. 282:1432-1444.
Diffraction pattern of CFIm25, a pre-mRNA 3’-end processing factor. Image by Qin Yang, graduate student in the Doublié lab.
Enzymes of the base excision repair pathway repair oxidative DNA damage.

Image by Fred Faucher, postdoc in the Wallace lab.

A human fibroblast cell infected with Toxoplasma gondii. Fluorescence microscopy was used to visualize the nuclei of the parasites and host cells (blue), the parasite plasma membrane (red), and the parasite dense granules (light green).  Image by Mike Wichroski, graduate student in the Ward lab.
The position of a DNA lesion in chromatin DNA can affect the ability of a DNA glycosylase to excise the damaged base. Image by Ian Odell, graduate student in the Pederson lab.
A thymine glycol-adenine base pair captured in the active site of a replicative DNA polymerase. Image by Pierre Aller, postdoc in the Doublié lab. See Aller P. et al., (2007) PNAS 104:814-818.
Rat cerebral artery visualized by immunofluorecence miscrocopy using an antibody against the protein PGP 9.5. Image courtesy of Nicole Bishop, UVM Microscopy Imaging Center; sample provided by Dr. Marilyn Cipolla, Departments of Neurology and Pharmacology.
Scanning electron micrograph of Streptococci. Image courtesy of Michele von Turkovich, UVM Microscopy Imaging Center; sample provided by Dr. Grace Spatafora (Middlebury College).
Crystal structure of Methanocaldococcus janischii 8-oxoguanine DNA glycosylase in complex with 8-oxoG. Image by Fred Faucher, postdoc in Doublié lab.
  • What our students have to say...

    I knew I wanted to be a part of MMG the first day I arrived at UVM. Our department is so welcoming and helpful. The faculty will never hesitate to lend a helping hand and will work with you to accomplish all the goals you set forth for yourself. The advising and counseling provided in MMG is unmatched at UVM. The MMG majors provide a curriculum that allows you to dive directly into your interests and explore unique questions with hands on experiences. From the very first semesters exploratory caffeine resistance experiments to mammalian cell culture in some of the more advanced laboratories, MMG is a very participant friendly course load. You will be able to explore the many facets of the microscopic world within a challenging yet always interesting and interactive experience. I loved my experience with MMG and the faculty could not have been more helpful throughout my attendance at UVM. The small department filled with numerous amazing faculty provides one of the best areas of study at UVM.

    Sam (Molecular Genetics), graduated 2014
Seminar
The evolution of antimicrobial resistance: inside and out, forwards and backwards by Brandon Ogbunugafor

Wed February 10th, 2016 at 9:30 AM
Stafford 410

Seminar
Dissecting of membrane fusion pathways by Leonid Chernomordik

Wed February 24th, 2016 at 9:30 AM

Seminar
TBA by David Baum

Wed March 30th, 2016 at 9:30 AM