Brian E. Eckenroth
Brian received a B.S. in Biochemistry in 1996 from the University of Maine in Orono, ME. From 1996-2002 he worked in an industrial setting at Idexx Laboratories Inc. in Westbrook, ME. He spent a year working in Quality Control and Optimization of a commercial ELISA for detection of antibiotics before moving to Research and Development. He spent two years developing products directed toward monitoring food processing safety and three years on clinical chemistry assay development for use in the veterinary field. Brian received a Ph.D in Biochemistry from The University of Vermont in 2007 studing the structural and functional dependence of Selenocysteine in mammalian thioredoxin reductase with Dr. Robert Hondal.
A member of the Doublié Laboratory
Eckenroth, B., Harris, K., Turanov, A.A., Gladyshev, V.N., Raines, R.T., Hondal, R.J. Semisynthesis and Characterization of Mammalian Thioredoxin Reductase Biochemistry 2006 Apr 25; 45(16): 5158-5170
Eckenroth, B.E., Rould, M.A., Hondal, R.J., Everse, S.J. Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases. Biochemistry 2007 Apr 24; 46(16): 4694-4705
Eckenroth, B.E., Lacey, B.M., Lothrop, A.P., Harris, K.M., Hondal, R.J. Investigation of the C-Terminal Redox Center of High M(r) Thioredoxin Reductase by Protein Engineering and Semisynthesis Biochemistry 2007 Aug 21; 46(33): 9472-9483