Dr. Douglas I. Johnson
Yeast Biofilm Formation and Virulence
From 1988 to 2016, Dr. Johnson’s research group studied Cdc42-dependent cell signaling pathways in the yeasts Saccharomyces cerevisiae, Schizosaccharomyces pombe, and Candida albicans. Most recently, his group identified small molecules that inhibited biofilm formation and the morphological budded-to-hyphal transition in the pathogenic yeast C. albicans.
Dr. Johnson is the Director of the MMG Undergraduate Program as well as the Director of the CALS Honors College Program. He teaches courses pertaining to introductory microbiology, clinical microbiology, bacterial infectious disease, cell signaling, and the cell division cycle. He also oversees the Undergraduate Research courses for MMG majors. He is in the process of writing a reference book on “Bacterial Pathogens and their Virulence Factors” for Springer International Books. He teaches all or part of the following courses:
MMG 002: Unseen Worlds – Microbes and You
Toenjes, K.A., B.C. Stark, K.M. Brooks, D.K. Butler, and D.I. Johnson. Inhibitors of cellular signaling are cytotoxic or block the budded-to-hyphal transition in the pathogenic yeast Candida albicans. J Med Microbiol. 2009 Jun;58(Pt 6):779-90.
Midkiff, J., N. Borochoff-Porte, D. White, and D.I. Johnson. Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways. PLoS ONE 2011 6:e25395.
Grald, A., P. Yargosz, S. Case, K. Shea, and D.I. Johnson. Small molecule inhibitors of biofilm formation in laboratory and clinical isolates of Candida albicans. J. Med. Microbiol. 2012. 69:109-114