Dr. Julie Dragon

Dr. Julie  Dragon
Assistant Professor

 

Director of the Bioinformatics Shared Resource (BSR)

In 2009, Dr. Dragon joined the Vermont Genetics Network (VGN) at UVM. She served as a data analyst in the VGN Bioinformatics Core and Outreach Team, assisting researchers with microarray data analysis and supported the Outreach Team with technology transfer and science education. In 2011 she transferred to the Bioinformatics Shared Resource (BSR) where she has since provided bioinformatics service for numerous investigators. In 2014 she became director of the shared resource.

In 2016, Dr. Dragon took over instruction of MMG232, Methods in Bioinformatics, which she will teach in the spring semester annually.

Dr. Dragon supports three large genomics research collaboratives on campus, the Vermont Immunobiology/Infectious Diseases Center (VCIID), the Structure and Function of DNA Repair Enzymes (SFDRE) Program Project, and the Vermont Breast Cancer Molecular Characterization Laboratory (VTBCMCL). In addition, she supports numerous genomics projects for investigators at UVM and Dartmouth University.

Her main research interests include experimental design, differential expression on coding and non-coding RNA, DNA sequence variation, and systems biology. In addition, she supports metagenomics investigations, as well as investigations of DNA methylation, chromatin interactions, and chromosomal rearrangements.

Principal Component Analysis of genome-wide mRNA expression from asbestos treated mesothelial cell lines compared to untreated cell lines. Pleural cells (green and blue) show an increase response to treatment as compared to peritoneal cells (red and purple). A = asbestos, C = control

Principal Component Analysis of genome-wide mRNA expression from asbestos treated mesothelial cell lines compared to untreated cell lines. Pleural cells (green and blue) show an increase response to treatment as compared to peritoneal cells (red and purple). A = asbestos, C = control

Heatmap representation of mRNA expression from pleural and peritoneal mesothelial cell lines in response to asbestos treatment in a select set of genes.

Heatmap representation of mRNA expression from pleural and peritoneal mesothelial cell lines in response to asbestos treatment in a select set of genes.


Office:
004 Hills
802-656-7777
julie.dragon@uvm.edu
Lab Website

 

BACKGROUND

Dr. Dragon received her BA in Anthropology from the University of Florida and her PhD in Plant Biology from the University of Vermont (UVM). She was a visiting professor at Middlebury College for one year teaching Ecology and Plant Biology, and then completed a two-year postdoctoral fellow in the Department of Plant Science at McGill University researching plant hybridization and salt tolerance before joining the Vermont Genetics Network (VGN) as a research professor at Norwich University. From Norwich, she served as a data analyst in the VGN Bioinformatics Core and Outreach Team, assisting researchers with microarray data analysis and supported the Outreach Team with technology transfer and science education. She has been the director of UVM’s Bioinformatics Shared Resource for two years.

LAB MEMBERS

Ramiro Barrantes-Reynolds
        Research Specialist
Dave Shirley
        Research Specialist
Marni Slavik
        Research Specialist

SELECTED PUBLICATIONS

Browne G, Dragon JA, Hong D, Messier TL, Gordon JA, Farina NH, Boyd JR, VanOudenhove JJ, Perez AW, Zaidi SK, Stein JL, Stein GS, Lian JB. MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells. Tumour Biol. 2016 Jan 9. [Epub ahead of print]

Silva MC, Morrical MD, Bryan KE, Averill AM, Dragon J, Bond JP, Morrical SW. RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects. DNA Repair (Amst). 2016 Jun;42:44-55

Dragon J, Thompson J, MacPherson M, Shukla A. Differential Susceptibility of Human Pleural and Peritoneal Mesothelial Cells to Asbestos Exposure. J Cell Biochem. 2015 Aug;116(8):1540-52

Saulnier Sholler GL, Bond JP, Bergendahl G, Dutta A, Dragon J, Neville K, Ferguson W, Roberts W, Eslin D, Kraveka J, Kaplan J, Mitchell D, Parikh N, Merchant M, Ashikaga T, Hanna G, Lescault PJ, Siniard A, Corneveaux J, Huentelman M, Trent J. Feasibility of implementing molecular-guided therapy for the treatment of patients with relapsed or refractory neuroblastoma. Cancer Med. 2015 Jun;4(6):871-86

Case LK, Wall EH, Osmanski EE, Dragon JA, Saligrama N, Zachary JF, Lemos B, Blankenhorn EP, Teuscher C. Copy number variation in Y chromosome multicopy genes is linked to a paternal parent-of-origin effect on CNS autoimmune disease in female offspring. Genome Biol. 2015 Feb 10;16:28