Dr. Stephanie Phelps
Undergraduate and Graduate Instruction
Stephanie Phelps received her B.Sc. in Biology from McGill University in 1988. She worked as a research associate in the Department of Cell Biology at Baylor College of Medicine and at the University of Michigan in the Department of Human Genetics. While at U of M, she conducted research on the structure and function of the gene responsible for Duchenne Muscular Dystrophy. Stephanie joined MMG in the fall of 1997 to support the undergraduate molecular genetics laboratories. During that time, she conducted research towards a graduate degree with Dr. Nicholas Heintz. In 2004, she was awarded a master’s degree from UVM for her work entitled "Characterization, modification and analysis of bacterial artificial chromosomes containing the human p53 gene." She became faculty that same year and is currently the course coordinator for MMG104 (Introduction to Recombinant DNA Technology), MMG201 (Molecular Cloning), and MMG203 (Mammalian Cell Culture in Molecular Biology). She continues to do research with Dr. Heintz, but is now focused on modification of a vector containing the gene for human Nox2. The hope is that the vector will be used for ex vivo gene therapy for patients with chronic granulomatous disease (CGD).
Phelps SF, Illenye S, Heintz NH: Manipulating genes and gene copy number by BAC transfection. In Cancer Genomics and Proteomics: Methods and Protocols (The Humana Press, Inc.), September 2007.
Montigny WJ, Phelps SF, Illenye S and Heintz NH: Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells. Biotechniques 2003; 35(4):796-807.
Lumeng C, Phelps S, Crawford GE, Walden PD, Barald K, and Chamberlain JS: Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases. Neurosci 1999; 2(7):611-617.
Lumeng CN, Phelps SF, Rafael JA, Cox GA, Hutchinson TL, Begy CR, Adkin E, Wiltshire R and Chamberlain JS: Characterization of dystrophin and utrophin diversity in the mouse. Hum Mol Genet 1999; 8(4):593-599
Im WB*, Phelps SF*, Copen EH, Adams EG, Slightom JL and Chamberlain JS: Differential expression of dystrophin isoforms in multiple strains of mdx mice. Hum Mol Genet 1996; 5:1149-1153.
Phelps SF, Hauser MA, Cole NM, Rafael JA, Hinkle RT, Faulkner JA, and Chamberlain JS: Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice. Hum Mol Genet 1995; 4:1251-1258.