University of Vermont

College of Medicine

Vermont Medicine Magazine

DEPARTMENT OF Biochemistry ~ 2014 Annual Report

Gary Stein, Ph.D., Chair

The Department of Biochemistry is at the forefront of biomedical research and education. Committed to transdisciplinary initiatives, biochemistry faculty and students are collaborating with colleagues throughout the College of Medicine, the University and The University of Vermont Medical Center to transcend traditional boundaries.

In education, under the leadership of Paula Tracy, Ph.D., as Foundations director and Stephen Everse, Ph.D., as director of cellular and molecular biology, transformative strategies in the first-year medical curriculum are transitioning classroom-based teaching to interactive learning experiences that prepare physicians with life-long capabilities to access advances in the biology and practice of medicine. Janet Stein, Ph.D., has aligned our graduate curriculum with the escalating requirements to understand and experience transdisciplinary perspectives and skillsets for biomedical research. Christopher Francklyn, Ph.D., with Beth Bouchard, Ph.D., and Jay Silveira, Ph.D., have been working with colleagues in the Department of Microbiology and Molecular Genetics and in Chemistry to enhance the teaching and laboratory components of our undergraduate biochemistry program.

Service and outreach to the College of Medicine, the University, and the community and beyond is a priority. The Biochemistry faculty, students and staff engage in securing funds and contribute to the patient support, education and advocacy programs of the American Heart Association and the American Cancer Society. They participate in an extensive series of initiatives that are dedicated to cancer and cardiovascular disease prevention, maximally effective treatment and sustained recovery. Services to the biomedical research community include leadership for grant review panels of the National Institutes of Health and disease-based foundations. Biochemistry faculty serve on scientific advisory boards for biotechnology and pharmaceutical industries and as science policy advisors for foreign governments.

Department of Biochemistry research contributions in cancer and cardiovascular disease continue to be significant, far reaching and relevant from fundamental mechanistic and clinical perspectives. Prominent advances include breakthroughs in understanding genetic and epigenetic parameters of cell cycle and growth control, genome instability, the biology and pathology of coagulation and thrombosis, breast and prostate cancer metastasis to bone and regulatory as well as clinical implications from resolution of Thioredoxin reductase activity.

Last modified January 28 2015 01:58 PM