University of Vermont

The University of Vermont Cancer Center

trials_support

Supportive Care Clinical Trials

The University of Vermont Cancer Center has many trials specifically focused on supportive care.

Status: Active - Recruiting
Study Title: VCC 1109: An Internet-Based Weight Loss and Exercise Intervention for Breast Cancer Survivors: The IWEB Program
Purpose: The purpose of this study is to test the effectiveness of a behavioral weight loss and exercise intervention delivered via the internet at different cancer centers in New England.  The research is being done because many women who are treated for breast cancer are overweight and treatment for breast cancer is often accompanied by weight gain. Individuals who are overweight may be more likely to have their breast cancer come back. Also women who exercise at least three hours a week seem to have less chance of their cancer coming back. The investigators hope to identify an effective weight loss and exercise intervention for breast cancer survivors that can be easily accessed by many people.
ClinicalTrials.gov Identifier: NCT01728506
Primary/Site/Co Investigator: Kim Dittus, MD
Contact: Karen Wilson (802) 656-4101
Information: http://www.clinicaltrials.gov/ct2/show/NCT01728506?term=NCT01728506&rank=1
Institution Number: CHRMS M12-109, VCC 1109
Protocol Research Type: Investigator Initiated
Status: Active - Recruiting
Study Title: Skeletal Muscle Function in Cancer
Purpose: Patients suffering from cancers, such as lung or pancreas, often experience significant muscle atrophy. Muscle loss can result in weakness, contribute to fatigue and impair function at diagnosis, during therapy and may continue beyond oncologic treatment.

The long term goal of our research effort is to better understand the nature of skeletal muscle atrophy and dysfunction in patients with cancers associated with weight loss. The immediate purpose of this submission is to obtain preliminary data on a small number of patients to support a larger-scale research study. Specifically, we are interested in evaluating whether individuals with lung and pancreatic cancer experience depletion of myosin in their skeletal muscle and/or any evidence of excessive myosin proteolysis or decreased myosin gene transcription.

ClinicalTrials.gov Identifier: N/A
Primary/Site/Co Investigator: Kim Dittus, MD
Contact: Karen Wilson (802) 656-4101
Information: N/A
Institution Number: CHRMS M11-109, VCC 1011
Protocol Research Type: Investigator Initiated
Status: Active - Recruiting
Study Title: VCC 1206: Predictors of Dyspnea/Fatigue Syndrome in Breast Cancer Survivors
Purpose: Fatigue and shortness of breath with activity are common side effect of cancer therapies and can last after cancer therapy is finished.  The purpose of this study is to understand the reasons why fatigue and shortness of breath are so common.  The research project will examine physical measures and how fatigue and shortness of breath feel to you before chemotherapy, at the end of chemotherapy and again after 6 months of being off chemotherapy.  We hope to identify causes of fatigue and shortness of breath to help us determine who is most at risk of becoming fatigue and short of breath.
ClinicalTrials.gov Identifier: NA
Primary/Site/Co Investigator: Kim Dittus, MD, PhD
Contact: Karen Wilson (802) 656-4101
Information: NA
Institution Number: VCC  1206
Protocol Research Type: Investigator Initiated
Status: Active - Recruiting
Study Title: VCC 1311: Behavioral Weight Loss and Exercise After Treatment (BEAT): Predictors of Weight Loss Success in Overweight Breast Cancer Survivors
Purpose: The purpose of this study is to find out how well a behavioral weight loss and exercise intervention works and to understand what factors predict weight loss and exercise success.  The research is being done because many women who are treated for breast cancer are overweight and individuals who are overweight may be more likely to have their breast cancer come back.  We don’t know for sure if weight loss improves outcomes related to breast cancer but we know it has other health benefits.  Women who are more physically active may be less likely to have their breast cancer come back.  We hope to identify how to best tailor weight loss and exercise programs to help breast cancer survivors make the lifestyle changes needed to lose weight and exercise.
ClinicalTrials.gov Identifier: NCT02052115
Primary/Site/Co Investigator: Kim Dittus, MD, PhD
Contact: Karen Wilson (802) 656-4101
Information: https://clinicaltrials.gov/ct2/show/NCT02052115?term=02052115&rank=1
Institution Number: VCC  1311
Protocol Research Type: Investigator Initiated
Status: Active - Recruiting
Study Title: VCC 1316: Resistance Exercise Training to Improve Skeletal Muscle Atrophy/Dysfunction in Individuals with Cancer
Purpose: This research study is designed to determine whether resistance exercise training can lessen or avoid the decline in muscle size and function associated with cancer and its treatment. 
ClinicalTrials.gov Identifier: N/A
Primary/Site/Co Investigator: Kim Dittus, MD, PhD
Contact: Karen Wilson (802) 656-4101
Information: N/A
Institution Number: CHRMS 14-095
Protocol Research Type: Investigator Initiated
Status: Active - Recruiting
Study Title: A221301: Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) in Patients Receiving Highly Emetogenic Chemotherapy (HEC)
Purpose: The purpose of this study is to determine if the use of olanzapine in combination with antiemetic therapy can significantly reduce nausea and vomiting in a large number of patients receiving chemotherapy.
ClinicalTrials.gov Identifier: NCT02116530
Primary/Site/Co Investigator: Steve Ades, MD
Contact: Karen Wilson (802) 656-4101
Information: http://www.clinicaltrials.gov/ct2/show/NCT02116530?term=A221301&rank=1
Institution Number: CHRMS 15-113
Protocol Research Type: Cooperative Group
Status: Active - Closed to Accrual
Study Title: Exercise Training for the PrEvention of Cancer Thrombosis (EXPECT) Pilot
Purpose: You are being invited to take part in a research study that will help us understand the importance of exercising during chemotherapy to prevent blood clots among cancer patients. 
ClinicalTrials.gov Identifier: NCT01853202
Primary/Site/Co Investigator: Susan G. Lakoski, MD
Contact: Elizabeth Eldridge (802) 656-2178
Information: http://clinicaltrials.gov/ct2/show/NCT01853202?term=NCT01853202&rank=1
Institution Number: M13-171, VCC 1220
Protocol Research Type: Investigator Initiated
Status: Active - Closed to Accrual
Study Title: A Phase 3, Multicenter, Randomized, Double-Blind, Active-Controlled Study of the Safety and Efficacy of Rolapitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Subjects Receiving Moderately Emetogenic Chemotherapy (MEC).

Purpose: The purpose of this study is to determine whether administration of rolapitant with granisetron and dexamethasone (common anti-emetics used with chemotherapy administration) improves chemotherapy-induced nausea and vomiting (CINV).

ClinicalTrials.gov Identifier: NCT01500226
Primary/Site/Co Investigator: Farrah Khan, MD
Contact: Kate Murray (802) 656-9401
Information: http://clinicaltrials.gov/ct2/show/NCT01500226?term=TS-P04834&rank=1
Institution Number: M12-247
Protocol Research Type: Industry Sponsored

Last modified December 11 2014 04:19 PM